Q86VF5 2-acylglycerol MOGAT3 9606 None SL-0198 Endoplasmic reticulum membrane {ECO:0000269|PubMed:27184406}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:27184406}. UNIPROT Q86VF5 UNIPROT Q496A6 UNIPROT Q496A7 UNIPROT Q496A8 UNIPROT Q9UDW7 Pfam PF03982 OMIM 610184 DisGeNET 346606 Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG) (PubMed:28420705). {ECO:0000269|PubMed:12618427, ECO:0000269|PubMed:27184406, ECO:0000269|PubMed:28420705}. P07339 EBI-25840151 0.56 G5E9A7 EBI-25843901 0.56 P28799 EBI-25862183 0.56 O76024 EBI-25900416 0.56 Q7Z699 EBI-25933765 0.56 GO:0005789 GO:0016021 GO:1990578 GO:0003846 GO:0004144 GO:0006071 GO:0006629 GO:0006640 GO:0019432 Transmembrane UniProt Sequence Analysis {ECO:0000255} MGVATTLQPPTTSKTLQKQHLEAVGAYQYVLTFLFMGPFFSLLVFVLLFTSLWPFSVFYLVWLYVDWDTPNQGGRRSEWIRNRAIWRQLRDYYPVKLVKTAELPPDRNYVLGAHPHGIMCTGFLCNFSTESNGFSQLFPGLRPWLAVLAGLFYLPVYRDYIMSFGLCPVSRQSLDFILSQPQLGQAVVIMVGGAHEALYSVPGEHCLTLQKRKGFVRLALRHGASLVPVYSFGENDIFRLKAFATGSWQHWCQLTFKKLMGFSPCIFWGRGLFSATSWGLLPFAVPITTVVGRPIPVPQRLHPTEEEVNHYHALYMTALEQLFEEHKESCGVPASTCLTFI 341