Q8BVF2 Phosducin-like Pdcl3 10090 None SL-0198 Cytoplasm {ECO:0000269|PubMed:27496612}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9H2J4}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9H2J4}. UNIPROT Q8BVF2 UNIPROT Q3TH06 UNIPROT Q99JX2 UNIPROT Q9D0W3 Pfam PF02114 Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation (PubMed:26059764). Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding (By similarity). Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes (By similarity). Modulates the activation of caspases during apoptosis (By similarity). {ECO:0000250|UniProtKB:Q4KLJ8, ECO:0000250|UniProtKB:Q9H2J4, ECO:0000269|PubMed:26059764}. P68510 EBI-8586548 0.35 P35279 EBI-11566531 0.35 GO:0005737 GO:0005829 GO:0005783 GO:0005654 GO:0048471 GO:0097356 GO:0032991 GO:0044183 GO:0043184 GO:0030036 GO:0001525 GO:0006915 GO:0034605 GO:0061077 GO:1903645 GO:2000059 GO:0045766 GO:0001938 GO:0010628 GO:0006457 GO:0050821 GO:0050730 Unknown UniProt Sequence Analysis MQDPNADTEWNDILRKKGILPPKESLKELEEEEAEKEEQLLQQSVVKTYEDMTLEELEENEDEFSEEDERAIEMYRQQRLAEWKATQLKNKFGEVLEISGKDYVQEVTKAGEGLWVILHLYKQGIPLCSLINHHLSGLARKFPDVKFIKAISTTCIPNYPDRNLPTVFVYREGDIKAQFIGPLVFGGMNLTIDELEWKLSESGAIKTALEENPKKPIQDLLLSSVRGPVPMRRDSDSEDD 240