NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Mitosis initiation protein fs(1)Ya - Drosophila melanogaster - NucEnvDB

Mitosis initiation protein fs(1)Ya (Drosophila melanogaster)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	Mitosis initiation protein fs(1)Ya
Accession Code	P25028
Gene	fs
Organism	Drosophila melanogaster (Taxonomy: 7227)
Part of Reference Proteome?	Yes
Sequence (Length: 696)
MSFSNVLIMRQPDEGKCHICKRVFCCGKCRQKHQFKAHAIAVREPLGLRSAGGGIIEHRHQMESGATTIYVFCPICERRPLLLREEMHGELLAHIETCHLPLRCRKCQRNYTRVDDLREFSKCVDQQQSC TDVTGATETSKATLKKAANSTAISTQTSPSVTPISLINMRWKAKSRVTHEEFISDSVSSIRNLSSFSNSSIRRSIGQLGVNPSETMEKGKVIRSTSTPLHVESVFAKPKEPITFNASTGGHVSSIYHEEP SPTPESNPVQQQQQQQQPLQQRAWKMGARNKMSAATPLRQVMSKSIQKAFVEHGGMMVHQPPSAVVQRRVRLDLSEHSSHEAAGSSALDLRLSPAMRRTQSESSASEVNSGSSSSYSTSRNADLCKRQFL LSAQKLTTESIIITRTNSSSQKTSSTVYNSCESVEIIRSTSESAEVCHVPAITPIRVTGAGINKKQIKFETPPKSSQQMRSNGEGDETKDQFFTPEPGTPEIPERRHRQAIVPRQLSGEFSPKKDKPKEK GLAVMALISPPLQQPRVRPPLRECRQQRVYSGVQDVGEPEVVDAEEEDEVFRPTNASTCNDKKLEAPNSGRLWSLMSSMMRLPASLRGEREKDRDRDRDSDKENAGSGSLIRRCASIAGSLVRPSARDSS MEDQQCLKRKRTQTLDSQYCSPLSPSSSSKRYRIRPREPIERMRRQ

Subcellular Location

Description
Nucleus envelope. Nucleus, nucleoplasm. Cytoplasm. Note=In the nuclear envelope during interphase to metaphase. And in the nucleoplasm and cytoplasm during anaphase and telophase.
Position in the Nuclear Envelope
Location	Location ID	Description
Nuclear Envelope	SL-0178	The nuclear envelope is a membrane system which surrounds the nucleoplasm of eukaryotic cells. It is composed of the nuclear lamina, nuclear pore complexes and two nuclear membranes. The space between the two membranes is called the nuclear intermembrane space.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Cytoplasm (GO:0005737) Nuclear Envelope (GO:0005635) Nuclear Lamina (GO:0005652) Nucleoplasm (GO:0005654)

Biology & Function

Description
Cell cycle-dependent nuclear envelope component required for embryonic mitosis.
Assigned Ontology terms

Biological Process	Cell Division (GO:0051301) Chromatin Organization (GO:0006325) Chromosome Condensation (GO:0030261) DNA Replication (GO:0006260) Mitotic Cell Cycle (GO:0000278) Nucleus Organization (GO:0006997) Pronuclear Fusion (GO:0007344)
Molecular Function

Protein-Protein Interactions

Interactions with Nuclear Envelope proteins (1 interactors)

Partner (NucEnvDB)		IntAct	Confidence score
P08928	Lamin Dm0	EBI-872894	0.27
Interactions with other proteins (3 interactors)

Partner (UniProt)		IntAct	Confidence score
P19889	60S acidic ribosomal protein P0 (Apurinic-apyrimidinic endonuclease) (EC 3.1.-.-)	EBI-8296323	0.40
P02283	Histone H2B	EBI-872898	0.27
O61307	Teneurin-m (Tenm) (Odd Oz protein) (Tenascin-like protein)	EBI-9946542	0.35

Cross-References

Database	Links
UNIPROT	P25028 Q8T057 Q9W4W0 Q9W4W1
PROSITE	PS00028

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