NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Fidgetin-like protein 1 - Xenopus tropicalis - NucEnvDB

Fidgetin-like protein 1 (Xenopus tropicalis)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Fidgetin-like protein 1
Accession Code	A4IHT0
Gene	fignl1
Organism	Xenopus tropicalis \| Tropical clawed frog (Taxonomy: 8364)
Part of Reference Proteome?	Yes
Sequence (Length: 656)
MQVPESSLAHLSEWQRDAFVLSSGTCLPQQKAEVYRAHLAQIQYAWANSEISEASAVHLFKKYAEKYSAIIDSDKLEIGLNNYADSILTLAKCQRNESDKWQSSLTTNNVLKLKSVQDMAVAGRRTQLSK SSADASVRVGNGINTSGYSAGLGNNVLRNSGYTVPHAALSDCQMPGGSANFLQKPKISAFTIANTTSVANTSSNTLINNSISMTSSLMQSNEDKDPASFSGHMFLPTTSVHSGKRKAYSALGNESSDIKP NPLVQRQLTNKEATCESGFKTAKEQLWVDQQKKYSNQPQRNPSPLYGGAKKSLGAARSRGLHGKFVPPVPRQEDVQDSNRKVYGQGNSEMNAPSDERLKNIEPKMIELIMSEIMDHGPPLNWDDIAGLEF AKTTIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIACQSGATFFSISASSLTSKWVGEGEKMVRALFTVARCHQPAVIFIDEIDSLLSQRGEGEHESSRRIKTEFLVQLDGATTSSDDR ILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVVSLMAKEHCSLAEQEVEAIVLQADGFSGADMTQLCREAALGPIRSIQLMDISTITPEQVRPIAYIDFQSAFLVVRPSVSQKDLELYENWNK TFGCGR

Subcellular Location

Description
Nucleus {By SimilarityUniProtKB:Q6PIW4}. Cytoplasm {By SimilarityUniProtKB:Q8BPY9}. Cytoplasm, perinuclear region {By SimilarityUniProtKB:Q8BPY9}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Nuclear Chromosome (GO:0000228) Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
May be involved in DNA double-strand break (DBS) repair via homologous recombination (HR). May regulate osteoblast proliferation and differentiation (By similarity). {By SimilarityUniProtKB:Q6PIW4}.
Assigned Ontology terms

Biological Process	ATP Metabolic Process (GO:0046034)
Molecular Function	ATP Binding (GO:0005524) ATP Hydrolysis Activity (GO:0016887) Hydrolase Activity (GO:0016787) Magnesium Ion Binding (GO:0000287) Microtubule Severing ATPase Activity (GO:0008568) Protein-Macromolecule Adaptor Activity (GO:0030674)

Cross-References

Database	Links
UNIPROT	A4IHT0
Pfam	PF00004 PF17862 PF09336
PROSITE	PS00674

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