NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Protein SUPPRESSOR OF GENE SILENCING 3 - Solanum lycopersicum - NucEnvDB

Protein SUPPRESSOR OF GENE SILENCING 3 (Solanum lycopersicum)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	Protein SUPPRESSOR OF GENE SILENCING 3
Accession Code	A5YVF1
Gene	SGS3
Organism	Solanum lycopersicum \| Tomato (Taxonomy: 4081)
Part of Reference Proteome?	Yes
Sequence (Length: 633)
MSFSKWGGKPSNSSEKQKASSTPTVEEINRGVGDIGLNSEQNEGWEVYARKPKNKGGSSAGKQWAPQNPSPKAWGNQNTKAWGHPDVGKKSGTRNNAGSGRGSGNNWSTPSDPQKLARPHLYDGGFPSSA PVPPALKNGWDWSSRVASAHPKDNSQVAAAADDDKASEHDAEDNELDFLDESDDDLHSDDFDSDVGEMSYETRKKNPWFNQLFHSLDSLTVTEINEPERQWHCPACKGGPGAIEWFTGLQSLMTHAKTKG LRVKIHRELAELLEEDLRQRGTSVVPPGEVYGRWGGMEFKDKEIVWPPMVIIMNTRLDKDENDKWIGMGNQELLEYFSSYAAVKARHSYGPQGHRGMSLLIFEASAVGYIEADRLSEHFSENGRNRDAWE RRSARFYPGGKRLLYGYMADKKDIDNFNQHSAGKSKLKFEMRSYKEAVWNPAKQMREDNQQLIWFKNKAAKHQMQAKALEESLSLVSEKHRQTLEENKIVRLKTKMHHEQIKEEMEFQEQFFKDQIKIIH DARTAREDNFEKTQQEQREMVKQSNANTASVEDHRVRAEKVAKFIKLQDKEMEEFVEERENLMRTHDDRIAALRRKYWEEEVELERKFDLELSKLMEKYSPKQSDEVNSSGTM

Subcellular Location

Description
Cytoplasm, perinuclear region {Experimental EvidencePubMed:18165314}. Note=Accumulates in inclusion bodies in the cell periphery. May interact with the ER network from the perinuclear region out to the cell periphery (By similarity). {By Similarity}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
Required for post-transcriptional gene silencing and natural virus resistance.
Assigned Ontology terms

Biological Process	Defense Response To Virus (GO:0051607) RNA-Mediated Gene Silencing (GO:0031047) Regulation Of Defense Response To Virus (GO:0050688)
Molecular Function

Protein-Protein Interactions

Interactions with other proteins (1 interactors)

Partner (UniProt)		IntAct	Confidence score
Q764F6	Protein V2	EBI-15678029	0.54

Cross-References

Database	Links
UNIPROT	A5YVF1
Pfam	PF03468 PF03470

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