NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Probable spastin homolog Bm1_53365 - Brugia malayi - NucEnvDB

Probable spastin homolog Bm1_53365 (Brugia malayi)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Probable spastin homolog Bm1_53365
Accession Code	A8QFF6
Gene	Bm1_53365
Organism	Brugia malayi (Taxonomy: 6279)
Part of Reference Proteome?	Yes
Sequence (Length: 454)
MLHPQKLEQQNYETFNKAYLKSKQLVTEGVSIDEISSNNDEQRKRIAMEKYRMGIEYFEKALKISPDKVYPEKRSEVITHREAMKRNLEATKGRLSDLEKMFPSKGNRNLQHRPVQFVSPSISKPQTAQL SSRPISSEKKNINYSNARTRSNLLKGVDDKFGGPLLNEILNQDDVKMSDIIGAETAKRALEETVILPTVNPSLFSGLRQPAQGILLFGPPGNGKTLLARAVAGECGSTMFLNVSAASLTSKWVGDAEKIV RALFQIARNGQPTIIFIDEIDSILCERNEKETEVSRRMKTEFLIQMDGMLSSKDDRLLVIGATNRPEELDSAILRRFPKRILIDVPNAAARLKLIMSLLEKTKTSFDLGLTQRQILAEWTHGYSNSDLVA LCREAAMVPIRDLSRKDIKNLVSTELRPITLRDFEIAMKAIKPSTNERMLQKLRKYAATAGQSD

Subcellular Location

Description
Cytoplasm, cytoskeleton {By Similarity}. Cytoplasm, perinuclear region {By Similarity}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Cytoplasm (GO:0005737) Microtubule (GO:0005874) Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
Severs microtubules, probably in an ATP-dependent fashion. {By Similarity}.
Assigned Ontology terms

Biological Process
Molecular Function	ATP Binding (GO:0005524) ATP Hydrolysis Activity (GO:0016887) Isomerase Activity (GO:0016853) Microtubule Severing ATPase Activity (GO:0008568)

Cross-References

Database	Links
UNIPROT	A8QFF6
Pfam	PF00004 PF17862
PROSITE	PS00674

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