NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Kinetochore and Eb1-associated basic protein - Drosophila melanogaster - NucEnvDB

Kinetochore and Eb1-associated basic protein (Drosophila melanogaster)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	Kinetochore and Eb1-associated basic protein
Accession Code	F0JAI6
Gene	Kebab
Organism	Drosophila melanogaster (Taxonomy: 7227)
Part of Reference Proteome?	Yes
Sequence (Length: 548)
MSSMAKSPDMRTPGCCSPLRTKELLERQRSSRCTPAKGYLTPRNCQSPKHPEMRIPSIFVTDADYGLERPKQLLQRLERSLYRSSSASKVPPKHSLLASQNRQRTWEGPKTPEFRSRTNKTIPASEPRPR RAKELLEDLRSKHQGTPATKIPSQRNPKENQELSKSHTCIPSSEPQPIRPKLILERERQESITNRLASTSIDRLKTKPPRSSFTSSRLLVPQMGFSYPKDPKRLHESDKGIKLTTSKRKLDFKTELGTDW LRRELEKIGKEWRKKTDYQLRQLISGFVKQLVRLLPFNGITFSHLSRDCYVQQMVEALQQLQYTKKVNKSWLQTPNSTQAIAHVLELLNFLLDVLEHRKGEGMCALPVVSEKQRIEQLASASGTSYDVMS LQQKFENIKIEKERLNNYQESLMPESPVSKDMDKVTERDGNQDFVRLLDFQKETLHELQLQRLRLQEFSELVSLAKIKLKRCCKANKQCIEAFNDQIQDLADCVVLRNRNIGLLTQLHLNDNPKEEELHE RMKQLQRLYEDNYSNLLQLNIKPPQGSP

Subcellular Location

Description
Cytoplasm {Experimental EvidencePubMed:21912673}. Cytoplasm, perinuclear region {Experimental EvidencePubMed:21912673}. Chromosome, centromere, kinetochore {Experimental EvidencePubMed:21912673}. Cytoplasm, cytoskeleton, spindle {Experimental EvidencePubMed:21912673}. Note=During metaphase expressed in the kinetochores. During anaphase expression in the kinetochores progressively increases, and at late anaphase it is also expressed in the microtubules, specifically in the central spindle and centrosomal region. During telophase expression increases in the microtubules, and it is associated with residual spindle microtubules between chromosomes that have separated. At interphase it is expressed in the cytoplasm particularly around the nucleus. {Experimental EvidencePubMed:21912673}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Kinetochore (GO:0000776) Perinuclear Region Of Cytoplasm (GO:0048471) Spindle Microtubule (GO:0005876)

Biology & Function

Description

Assigned Ontology terms

Biological Process
Molecular Function	Kinetochore Binding (GO:0043515) Microtubule Binding (GO:0008017)

Protein-Protein Interactions

Interactions with other proteins (1 interactors)

Partner (UniProt)		IntAct	Confidence score
Q7JN06	Boundary element associated factor (Boundary element-associated factor of 32kD, isoform A)	EBI-198980	0.00

Cross-References

Database	Links
UNIPROT	F0JAI6 Q961C7 Q9VQ69

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