NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Tyrosine 3-monooxygenase - Schistosoma mansoni - NucEnvDB

Tyrosine 3-monooxygenase (Schistosoma mansoni)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Tyrosine 3-monooxygenase
Accession Code	O17446
Gene	TH
Organism	Schistosoma mansoni (Taxonomy: 6183)
Part of Reference Proteome?	Yes
Sequence (Length: 465)
MKMTMMCDESIEENNKSSTVELNHNEKDGRIHSIIINFHPITHEQSNNQFYIQTLHEILKYIIDKKLNLVHFETRPTLTLSNANRDVQYSCLITLEANEINMSLLYEELRGNSFISGINLLNNQESEDWY PKHISDLDKCQHLLRKFQPELQTDHPGFHDKVYRERREAIAKIAFQYKYGDRIPEVEYTKEEIETWGLVFTKMKAVHASRACREYIDGFQLLEKYCNYNSESIPQLQTICEFMHRTSGFRIRPVAGLVSP KDFLASLAFRVFQCTQYIRHHSRPMHTPEPDCIHELIGHMPMLVNRQFADFSQELGLASLGASEEEITRLSTLYWFTVEFGLCNENGETRALGAGIMSSYGELENAFSDLSVKEPFNINDAAVQVYDDVG YQKIYFVTESIESMKRELRNYINTSGKSTIPIYDPITETVHMKSRFSIRKELLKHVKEEIGQLDTLLNHSNYTLP

Subcellular Location

Description
Cytoplasm, perinuclear region {By SimilarityUniProtKB:P24529}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description

Assigned Ontology terms

Biological Process	Aromatic Amino Acid Metabolic Process (GO:0009072) Dopamine Biosynthetic Process (GO:0042416) Neurotransmitter Biosynthetic Process (GO:0042136)
Molecular Function	Iron Ion Binding (GO:0005506) Tyrosine 3-Monooxygenase Activity (GO:0004511)

Cross-References

Database	Links
UNIPROT	O17446
Pfam	PF00351
PROSITE	PS00367 PS51410

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