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NucEnvDB
A database of Nuclear Envelope Proteins and their Interactions
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BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 - Mus musculus - NucEnvDB
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (
Mus musculus
)
FASTA
TEXT
XML
Subcellular Location
Biology & Function
Cross-References
General Information
Protein Information
Protein Name
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
Accession Code
O54940
Gene
Bnip2
Organism
Mus musculus
| House mouse (Taxonomy:
10090
)
Part of Reference Proteome?
Yes
Sequence (Length: 326)
Show
MEGVELKEEWQDEDFPIPLPEDDSIEADTLDGTDPDRQPGSLEVNGNKVRKKLMAPDISLTLDPGEDSLWSDDLDEAGEVDLEGLDTPSENSDEFEWEDDLPKPKTTEVIRKGSITEYTATEEKGDGRRW
RMFRIGEQDHRVDMKAIEPYKKVISHGGYYGDGLNAIVVFAVCFMPESGQPNYRYLMDNLFKYVIGTLELLVAENYMIIYLNGATTRRKMPSLGWLRRCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVT
RPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQYEEEKFKKRQKRVDQELNGKQEPPKSEQ
Subcellular Location
Description
Show
Cytoplasm {
By Similarity
}. Cytoplasm, perinuclear region {
By Similarity
}. Note=Localizes to the nuclear envelope region and to other cytoplasmic structures. {
By Similarity
}.
Position in the Nuclear Envelope
Location
Location ID
Description
Perinuclear Region
SL-0198
The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology
Source
Annotation Type
Unknown
UniProt
Sequence Analysis
Assigned Ontology terms
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Cellular Component
Centriole
(
GO:0005814
)
Cytoplasm
(
GO:0005737
)
Cytosol
(
GO:0005829
)
Intracellular Membrane-Bounded Organelle
(
GO:0043231
)
Nuclear Envelope
(
GO:0005635
)
Nucleolus
(
GO:0005730
)
Perinuclear Region Of Cytoplasm
(
GO:0048471
)
Spindle Pole Centrosome
(
GO:0031616
)
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Biology & Function
Description
Hide
Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins (By similarity). {
By Similarity
}.
Assigned Ontology terms
Show
Biological Process
Apoptotic Process
(
GO:0006915
)
Blastocyst Development
(
GO:0001824
)
Centrosome Cycle
(
GO:0007098
)
Positive Regulation Of MAPK Cascade
(
GO:0043410
)
Positive Regulation Of Neuron Differentiation
(
GO:0045666
)
Positive Regulation Of Small GTPase Mediated Signal Transduction
(
GO:0051057
)
Striated Muscle Cell Differentiation
(
GO:0051146
)
Molecular Function
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Cross-References
Database
Links
UNIPROT
O54940
Q8K4H0
Pfam
PF12496
PF13716
PROSITE
PS50191
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National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory