NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

p5 - African swine fever virus Malawi LIL 20/1 - NucEnvDB

p5 (African swine fever virus Malawi LIL 20/1)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	p5
Accession Code	P0CA02
Gene	Mal
Organism	African swine fever virus Malawi LIL 20/1 (Taxonomy: 10500)
Part of Reference Proteome?	No
Sequence (Length: 2475)
MGNRGSSTSSRPPLSSEANIYAKLQDHIQRQTRPFSGGGYFNGGGDKNPVQHIKDYHIDSVSSKAKLRIIEGIIKAISKIGFKIDTKQPIEDILKDIKKQLPDPRAGSTFVKNAEKQETVCKMIADAINQ EFIDLGQDKLIDTTEGAASICRQIVLYINSLTHGLRAEYLDVHGSIENTLENIKLLNDAIKQLHERMVTEVTKAAPNEEVINAVTMIEAVYRRLLNEQNLQISILTNFIDNILTPTQKELDKLQTDEVDI IKLLNDTNSVLGTKNFGKVLSYTLCNLGIAASVANKINKALQRVGLKVEQYLQSKNWAEFDKELDLKRFSGLVSAENIAEFEKAVNLLRQTFNERHKILENNCAKKGGDEVKTPLDKRIEAQRLDRKHIL MEFLNKSTQAYNDFLENVKKIGIKLVKEIALTPNITRLRDALSRINDMGTIALDLSLIGFYTNAAAREERETFLTQLTLVKNVLEEISKTDPNFKNLYDSCFRLLQIIDFYTDIVQKKYGGGEDCECTRV GGAALTVEELGLSKAARSQVDLNQAINTFMYYYYVAQIYSNLTHNKQEFQSYEENYATILGDAIAGRLMQLDTEKNARINSPAVDLARGHVGPNPGGAQEVDWKAAVSAIELEYDVKRRFYRALEGLDLY LKNITKTFVNNIDSIQTVQQMLDGVRIIGRWFTEATGDTLAQVFESFPTSAGNDSNVFTDNAPAGHYYEKVAAEIQQGRSVGTLRPVRASQAKNIRDLIGRSLSNFQALKNIINAFARIGDMLGGEELRQ MVPMSPLQIYKTLLEYLQHSALSVGLKNLNQSEIGGQRMALAQTAEEAAQRVYLSTVRVNDALSSRWETEDMFFTFMLKSMAAKIFIVLGIYDMFERPEPVYKLIPTRMILGGADELEPEVIPEAAELYF RLPRLAEFYQKLFSFRDGNVQISMLPELEGIFSGLIRIIFMRPIELINIGDYSETEIRQLIKEINVIYQHFNLEYGEQEATKKALIHFVNEINRRFGVITRTEWEKFQRIVQEARTMNDFGMMNQTNYSI LPDEDGYTQSSQLLPSDRFIGPSSQPTPKWRPALYNIDSVDVQTGMLQPNSQWDLVQKFRKQLSEMFEDPSLQQELGKISYQELIRQAINELKKEHTDKIQIVSKLIQGSESLADTDVNKIFLFHETVIT GLNLLSAIYVLLNNFRNNIKGLDLDTIQKSIIEWLRETQPPDVNHANLLDWLGRKHGAISEIRNPGLVVKANNARLSEVYPDPTTDANTPQDRNLTTETLFAWIVQYVGIPAGGGVRPEQELAARYLVDN QRIMQLLLTNIFEITSSFNKMIQVRFPETSTAHVHLDFTGLISLIDSLMADTKYFLDLLRPHIDKNIIQYYENRSNPGSFYWLEEHLIDKLIKPPTDARGRPLPGGELGLEGVNQIINKTYTLLTKPYNV LQLRGGAQRRDAANIQINNNPQSSERFEQYGRVFSKLVFYDALENNSGLRVEQVALGDFRLSNLIRTNNAQEENTLSYWDNIALRTYANVNDAANNLRRYRLYGSDYGIQNNRSMMMVFNQLIASYITRF YDAPSGKIYLNLINAFANGNFSQAVMEMGYAHPDLARNNNAFGHRGDPTEQSVLLLSLGLILQRLIKDTNRQGLSQHLISTLTEIPIYLKENYRANLPLFNKMFNILISQGELLKQFIQYTNVQLARPNL TALLRANNDSVIYYNNNNVPMTGLSIGQAAMRGIGGVFRPNVTLMPLGDAQNNTSDIVRKRLVAVIDGIIRGSHTLADSAMEVLHELTDHPIYLETEEHFIQNYMSRYNKEPLMPFSLSLYYLRDLRIEN NEVYDPLLYPNLESGSPEFKLLYGTRKLLGNDPVQLSDMPGVQLIMKNYNETVVAREQITPTRFEHFYTHAIQALRFIVNIRSFKTVMTYNENTFGGVNLISEDRNDKPIITAGIGMNAVYSLRKTLQDV ISFVESSYQEEQINNIHKIVSPKGQTRTLGSNRERERIFNLFDMNIIPINVNALMRSIPLANIYNYDYSFEEIACLMYGISAEKVRSLNTAAPQPDVAEVLNIPNRPPINTREFMLKLLINPYVSVSITQ YGNELLSKGNAGYMSRIFRGDNALNMGRPKFLSDQIFNKVLFGSLYPTQFDYDEAGPSLAAGIQRGRERWGHPMSIYINQALHEIVRTIRLAETVRGLRNVIDRNQIIGELNAFRTQLEDTLREVNNLVQ TPEIQNNPTPEIIAAVQNWGQQYRAQITDLIDLIGNAGQANSMISLIQNINVQTAGAQLTALFNRRGLPAPPPRQVLQNDIEAIQWFMTIVINHPPILIAPFMLLVNNLKEFLNTLERYVYKTPRWLGPG TARIAQPPVGMAPGINMRHHTSYTENSVLTYITEQNREEGPWSIVKQVGVGIQKPTLVQIGKDRFDTRLIRNLIFITNVQRLLRLRLNLELSQFRNVLVSPDHIINPSITEYGFSITGPSETFSDKQYDS DIRIL

Subcellular Location

Description
[Polyprotein pp220]: Host cytoplasm, host perinuclear region {By SimilarityUniProtKB:Q08358}. Note=Found in perinuclear cytoplasmic viral factories during assembly. {By SimilarityUniProtKB:Q08358}. [p34]: Virion {By SimilarityUniProtKB:Q08358}. Host cytoplasm, host perinuclear region {By SimilarityUniProtKB:Q08358}. Note=Found in perinuclear cytoplasmic viral factories during assembly (By similarity). In the virion, located in the core shell, which functions like a matrix between the DNA-containing nucleoid and the inner envelope (By similarity). {By SimilarityUniProtKB:Q08358}. [p14]: Virion {By SimilarityUniProtKB:Q08358}. Host cytoplasm, host perinuclear region {By SimilarityUniProtKB:Q08358}. Note=Found in perinuclear cytoplasmic viral factories during assembly. In the virion, located in the core shell, which functions like a matrix between the DNA-containing nucleoid and the inner envelope. {By SimilarityUniProtKB:Q08358}. [p37]: Virion {By SimilarityUniProtKB:Q08358}. Host cytoplasm, host perinuclear region {By SimilarityUniProtKB:Q08358}. Host nucleus {By SimilarityUniProtKB:Q08358}. Note=Nuclear at early stages of infection. Found in perinuclear cytoplasmic viral factories during assembly. In the virion, located in the core shell, which functions like a matrix between the DNA-containing nucleoid and the inner envelope. {By SimilarityUniProtKB:Q08358}. [p150]: Virion {By SimilarityUniProtKB:Q08358}. Host cytoplasm, host perinuclear region {By SimilarityUniProtKB:Q08358}. Note=Found in perinuclear cytoplasmic viral factories during assembly. In the virion, located in the core shell, which functions like a matrix between the DNA-containing nucleoid and the inner envelope. {By SimilarityUniProtKB:Q08358}. [p5]: Virion {By SimilarityUniProtKB:Q08358}.
Position in the Nuclear Envelope
Location	Location ID	Description
Host Perinuclear Region	SL-0382	The host perinuclear region is the host cytoplasmic region just around the host nucleus. Note: This location is defined for viral proteins that appear in the perinuclear region of infected host cells
Membrane Topology
Topology	Source	Annotation Type
Lipid-Anchored	UniProt	By Similarity {ECO:0000250\|UniProtKB:Q08358}
Assigned Ontology terms

Cellular Component	Host Cell Nucleus (GO:0042025) Host Cell Perinuclear Region Of Cytoplasm (GO:0044220) Virion Component (GO:0044423)

Biology & Function

Description
[Polyprotein pp220]: Essential for the core assembly. Its myristoyl moiety may function as a membrane-anchoring signal to bind the developing core shell to the inner viral envelope. {By SimilarityUniProtKB:Q08358}. [p34]: The structural protein p34 is a component of the virus core shell. {By SimilarityUniProtKB:Q08358}. [p14]: The structural protein p14 is a component of the virus core shell. {By SimilarityUniProtKB:Q08358}. [p37]: The structural protein p37 is a component of the virus core shell. {By SimilarityUniProtKB:Q08358}. [p150]: The structural protein p150 is a component of the virus core shell. {By SimilarityUniProtKB:Q08358}.
Assigned Ontology terms

Biological Process
Molecular Function

Cross-References

Database	Links
UNIPROT	P0CA02

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