NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Tyrosine 3-monooxygenase - Phasianidae sp. - NucEnvDB

Tyrosine 3-monooxygenase (Phasianidae sp.)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Tyrosine 3-monooxygenase
Accession Code	P11982
Gene	TH
Organism	Phasianidae sp. (Taxonomy: 9006)
Part of Reference Proteome?	No
Sequence (Length: 491)
MPTPNISTSAAKGFRRAVSELDSKQAEAIMSPRFIGRRQSLIEDARKEREAAAAATDAAESTETIVFEEKDGRAMLNLFFMLKGVKTSPLSRALKVFETFEAKIHHLETRLSRKPREGTAELEYFVRCEV HSSDLNTFISSIKRVAEDVRTTKEDKFHWFPRKICELDKCHHLVTKFDPDLDLDHPGYSDQVYRQRRKSIAEIAFHYKHGDPIPRVEYTAEETATWKEVYSTLKSLYPTHACKEYLEAFNLLEKFCGYNE NNIPQLEEVSRFLKERTGFQLRPVRGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADKTFAQFSQDIGLASLGATDEEIEKLATLYWFTVEFGLCRQNGIVKAYGAGLLSSY GELIHSLSDEPEVRDFDPDAAAVQPCQDQPYQPVYFVSESFSDAKNKLRNYAAHIKRPFSVKYEPYTHSIELLDSPQTICHSLESVRDELHTLINALNVIS

Subcellular Location

Description
Cytoplasm, perinuclear region {By SimilarityUniProtKB:P24529}. Cell projection, axon {By SimilarityUniProtKB:P24529}. Note=Expressed in dopaminergic axons and axon terminals. {By SimilarityUniProtKB:P24529}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Axon (GO:0030424) Cytoplasm (GO:0005737) Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
Plays an important role in the physiology of adrenergic neurons.
Assigned Ontology terms

Biological Process	Aromatic Amino Acid Metabolic Process (GO:0009072) Courtship Behavior (GO:0007619) Dopamine Biosynthetic Process (GO:0042416) Grooming Behavior (GO:0007625) Neurotransmitter Biosynthetic Process (GO:0042136) Response To Growth Hormone (GO:0060416) Social Behavior (GO:0035176) Vocalization Behavior (GO:0071625)
Molecular Function	Iron Ion Binding (GO:0005506) Tyrosine 3-Monooxygenase Activity (GO:0004511)

Cross-References

Database	Links
UNIPROT	P11982
Pfam	PF00351 PF12549
PROSITE	PS00367 PS51410

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