NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Exocyst complex component 3 - Bos taurus - NucEnvDB

Exocyst complex component 3 (Bos taurus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Exocyst complex component 3
Accession Code	Q0V8C2
Gene	EXOC3
Organism	Bos taurus \| Cattle (Taxonomy: 9913)
Part of Reference Proteome?	Yes
Sequence (Length: 745)
MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVRHSQLAAAVENLKNIFSVPEIVRETQ DLIEHGELLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHSYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPKNWKEKMFTILDRTVTTRI EGTQADTRESDRMWLVRHLEIIRKYVLDDLIVAKNLLAQCFPPHYEIFRSLLRTYHQALSARMQDLAAEDLEANEIVSLLTWVLNTYTSVEMMGNAELAPEVDVALLEPLLSADVVSALLDTYMSTLTSN IIAWLRKALETDKKDWMKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKEEAQLYRDEHLRDRQHPHCYVQYMVAVVNNCQTFKESIVSLKRKYLKHEAEEGV SLSQPSMDGVLDAIAKEGCGSLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYRKRMIAEAHRRAVQEYLRAVMQKRISFRSAEERKDGAERMVREAEQLRFLFRKLASGFGE EMDSYCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAMRGDASRDMKQTIIETLEQGPAQASPDYVPIFKDIVVPSLNVAKLLK

Subcellular Location

Description
Cytoplasm {By SimilarityUniProtKB:Q62825}. Cytoplasm, perinuclear region {By SimilarityUniProtKB:Q62825}. Cell projection, growth cone {By SimilarityUniProtKB:Q62825}. Cell projection, neuron projection {By SimilarityUniProtKB:Q62825}. Midbody {ECO:0000250\|UniProtKB:O60645}. Golgi apparatus {ECO:0000250\|UniProtKB:O60645}. Note=Perinuclear in undifferentiated PC12 cells. Redistributes to growing neurites and growth cones during NGF-induced neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (By similarity). {ECO:0000250\|UniProtKB:O60645, By SimilarityUniProtKB:Q62825}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Exocyst (GO:0000145) Golgi Apparatus (GO:0005794) Growth Cone (GO:0030426) Midbody (GO:0030496) Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. {By Similarity}.
Assigned Ontology terms

Biological Process	Exocyst Localization (GO:0051601) Exocytosis (GO:0006887) Protein Transport (GO:0015031)
Molecular Function	SNARE Binding (GO:0000149)

Cross-References

Database	Links
UNIPROT	Q0V8C2
Pfam	PF06046

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