NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Transmembrane protein 184A - Bos taurus - NucEnvDB

Transmembrane protein 184A (Bos taurus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Transmembrane protein 184A
Accession Code	Q1RMW2
Gene	TMEM184A
Organism	Bos taurus \| Cattle (Taxonomy: 9913)
Part of Reference Proteome?	Yes
Sequence (Length: 414)
MTDTPGLLGTPLAWTPPARPAGPQMERAGNGSQGPGPLFLTSPLARGVSGVFVWAALVLTGHQIYLHLRSYTVPHEQRYIIRLLFIVPVYAFDSWLSLLLLGGHQHYIYFDSVRDCYEAFVIYSFLSLCF QYLGGESAIMAEIRGKPVRTSCFHGTCCLRGMTYSIGFLRFCKQATLQFCIVKPIMALVTIVLQAFGKYHDGDFNVRSGYLYITLVYNASVSLALYALFLFYSATRELLQPFEPVLKFLTIKAVIFLSFW QGLLLAILERCGVIPEVQVIDGSTVGAGTVAAGYQNFIICIEMLFASIALRYAFTCQVYSEKTESSPAPSAPMQSISSGLKETMSPQDIVQDAIHNFSPAYQKYTQQATQEAPRPGQGSVPSPRTPTHSP DGGPGGGRKGRNVEKRMLIPAEEL

Subcellular Location

Description
Cell membrane {Experimental EvidencePubMed:26769966}; Multi-pass membrane protein {Sequence Analysis}. Cytoplasm, perinuclear region {Experimental EvidencePubMed:26769966}. Cytoplasmic vesicle membrane {Experimental EvidencePubMed:26769966}; Multi-pass membrane protein {Sequence Analysis}. Early endosome membrane {ECO:0000250\|UniProtKB:Q3UFJ6}; Multi-pass membrane protein {Sequence Analysis}. Endosome {ECO:0000250\|UniProtKB:Q3UFJ6}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250\|UniProtKB:Q3UFJ6}. Note=Colocalizes with CAV1. {Experimental EvidencePubMed:26769966}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Transmembrane	UniProt	Sequence Analysis {ECO:0000255}
Assigned Ontology terms

Cellular Component	Cytoplasmic Vesicle Membrane (GO:0030659) Early Endosome Membrane (GO:0031901) Endosome (GO:0005768) Perinuclear Region Of Cytoplasm (GO:0048471) Plasma Membrane (GO:0005886) Secretory Granule Membrane (GO:0030667) Transport Vesicle Membrane (GO:0030658)

Biology & Function

Description
Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity). {By SimilarityUniProtKB:Q3UFJ6, By SimilarityUniProtKB:Q4QQS1}.
Assigned Ontology terms

Biological Process
Molecular Function	Heparin Binding (GO:0008201)

Cross-References

Database	Links
UNIPROT	Q1RMW2
Pfam	PF03619

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