NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

2-acylglycerol O-acyltransferase 2-A - Xenopus laevis - NucEnvDB

2-acylglycerol O-acyltransferase 2-A (Xenopus laevis)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	2-acylglycerol O-acyltransferase 2-A
Accession Code	Q2KHS5
Gene	mogat2
Organism	Xenopus laevis \| African clawed frog (Taxonomy: 8355)
Part of Reference Proteome?	Yes
Sequence (Length: 335)
MKIQFAPHNVPFERRLQTAAVLQWVFSFLALAQTCILLFFVLLFTRFWIISVVYGVWWFLDWDTPSKGGRRGEWLRRHVIWTYMKDYFPITLVKTADLDPQQNYVVGSHPHGVLVAGAFTNFCTEATGFH RLFPGITPYLLMLPLWFRAPFFRDYIMSGGLIPSDKDSASYLLKNKAGGNAVVIAVGGAPESLDARPGAFTLLIKNRKGFVRLAILHGASLVPVFSFGENELFDQVDNPRGSWLRKIQEKLQKMMGVALP LFHARGVFQYSFGLIPYRKPIATIVGKPIRVEENPNPSSEEVDKLHKIYMEELSKLFEEHKTKYNVPADKHLTFV

Subcellular Location

Description
Endoplasmic reticulum membrane {By SimilarityUniProtKB:Q3SYC2}; Multi-pass membrane protein {By SimilarityUniProtKB:Q3SYC2}. Cytoplasm, perinuclear region {By SimilarityUniProtKB:Q3SYC2}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Transmembrane	UniProt	Sequence Analysis {ECO:0000255}
Assigned Ontology terms

Cellular Component	Endoplasmic Reticulum Membrane (GO:0005789) Perinuclear Endoplasmic Reticulum Membrane (GO:1990578)

Biology & Function

Description
Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. {By SimilarityUniProtKB:Q3SYC2}.
Assigned Ontology terms

Biological Process	Glycerol Metabolic Process (GO:0006071) Monoacylglycerol Biosynthetic Process (GO:0006640) Triglyceride Biosynthetic Process (GO:0019432)
Molecular Function	2-Acylglycerol O-Acyltransferase Activity (GO:0003846)

Cross-References

Database	Links
UNIPROT	Q2KHS5
Pfam	PF03982

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