NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Synaptojanin-2-binding protein - Bos taurus - NucEnvDB

Synaptojanin-2-binding protein (Bos taurus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Synaptojanin-2-binding protein
Accession Code	Q3T0C9
Gene	SYNJ2BP
Organism	Bos taurus \| Cattle (Taxonomy: 9913)
Part of Reference Proteome?	Yes
Sequence (Length: 145)
MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIFVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGPQGEGEPSGIPIAMVLVPVFAL TMVAAWAFMRYRQRL

Subcellular Location

Description
Mitochondrion outer membrane {By SimilarityUniProtKB:Q9D6K5, By SimilarityUniProtKB:Q9WVJ4}; Single- pass type IV membrane protein {By SimilarityUniProtKB:Q9D6K5, By SimilarityUniProtKB:Q9WVJ4}; Cytoplasmic side {By SimilarityUniProtKB:Q9D6K5, By SimilarityUniProtKB:Q9WVJ4}. Cytoplasm, perinuclear region {By SimilarityUniProtKB:Q9D6K5, By SimilarityUniProtKB:Q9WVJ4}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Transmembrane	UniProt	Sequence Analysis {ECO:0000255}
Assigned Ontology terms

Cellular Component	Basolateral Plasma Membrane (GO:0016323) Cell Junction (GO:0030054) Mitochondrial Outer Membrane (GO:0005741) Neuromuscular Junction (GO:0031594) Neuron Projection (GO:0043005) Perinuclear Region Of Cytoplasm (GO:0048471) Postsynaptic Density Membrane (GO:0098839)

Biology & Function

Description
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction. {By SimilarityUniProtKB:Q9D6K5}.
Assigned Ontology terms

Biological Process	Cell-Cell Adhesion (GO:0098609) Chemical Synaptic Transmission (GO:0007268) Endocytosis (GO:0006897) Establishment Or Maintenance Of Epithelial Cell Apical/Basal Polarity (GO:0045197) Negative Regulation Of Angiogenesis (GO:0016525) Negative Regulation Of Endothelial Cell Migration (GO:0010596) Negative Regulation Of Endothelial Cell Proliferation (GO:0001937) Negative Regulation Of ERK1 And ERK2 Cascade (GO:0070373) Negative Regulation Of Sprouting Angiogenesis (GO:1903671) Receptor Clustering (GO:0043113) Receptor Localization To Synapse (GO:0097120) Regulation Of Notch Signaling Pathway (GO:0008593)
Molecular Function

Cross-References

Database	Links
UNIPROT	Q3T0C9
Pfam	PF00595
PROSITE	PS50106

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