NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Translin-associated protein X - Macaca fascicularis - NucEnvDB

Translin-associated protein X (Macaca fascicularis)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Translin-associated protein X
Accession Code	Q4R599
Gene	TSNAX
Organism	Macaca fascicularis \| Crab-eating macaque (Taxonomy: 9541)
Part of Reference Proteome?	Yes
Sequence (Length: 290)
MSNKEGSGGFRKRKHDNFPHNQRREGKDVNSSSPVMLAFKSFQQELDARHDKYERLVKLSRDITVESKRTIFLLHRITSAPDMEDILTESEIKLDGVRQKIFQVAQELSGEDMHQFHRAITTGLQEYVEA VSFQHFIKTRSLISMDEINKQLIFTTDDNGKENKTPSSDTQDEQFGTWRLRVTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYTLKQSLAKVENACYAL KVRGSEIPKHMLADVSSVKTEMIDQEEGIS

Subcellular Location

Description
Cytoplasm, perinuclear region {By Similarity}. Golgi apparatus. Nucleus {By Similarity}. Note=Expressed in the cytoplasm in the presence of TSN. Accumulate in the Golgi complex of mid-late pachytene spermatocytes (By similarity). {By Similarity}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Golgi Apparatus (GO:0005794) Nucleus (GO:0005634) Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis (By similarity). {By Similarity}.
Assigned Ontology terms

Biological Process	Cell Differentiation (GO:0030154) Spermatogenesis (GO:0007283)
Molecular Function	Metal Ion Binding (GO:0046872) Sequence-Specific DNA Binding (GO:0043565)

Cross-References

Database	Links
UNIPROT	Q4R599
Pfam	PF01997

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