NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Epsin-3 - Rattus norvegicus - NucEnvDB

Epsin-3 (Rattus norvegicus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Epsin-3
Accession Code	Q4V882
Gene	Epn3
Organism	Rattus norvegicus \| Norway rat (Taxonomy: 10116)
Part of Reference Proteome?	Yes
Sequence (Length: 608)
MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQV MALLKDEERLRQERTHALKTKERMALEGMGIGSGQLGFSRRSRGSPSSYTSASSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAEKGGRSWKGDDFPVANGAEPAGQRRRDREPEREERKEEEKLK TSQSSILDLADVFAPAPALPSTHCSADPWDIPGLRPNTEPSGSSWGPSADPWSPVPSGNALSRSQPWDLLPTLSSSEPWGRTPVLPSGPPITDPWAPSSPTPKLPSTGVDPWGASVETSNTSALGGASPF DPFAKPLESTEPMESRDSAQALPKGKSPSPVELDPFGDSSPSCKQNGVKETEALDLGVLGEALTQQPGKEARPCRTPESFLGPSASSLVNLDSLVKAPLAARTRNPFLTGLSAPSPTNPFGAGEQGRPTL NQMRTGSPALGLPPGGPVGVPLGSMTYSASLPLPLSSVPVGATLPASVSVFPQAGAFAPPPASLPQPLLPTSDPVGPLPPQAGTNPFL

Subcellular Location

Description
Cytoplasm, cell cortex {By Similarity}. Cytoplasm, perinuclear region {By Similarity}. Cytoplasmic vesicle, clathrin-coated vesicle {By Similarity}. Nucleus {By Similarity}. Note=Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus (By similarity). {By Similarity}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Cell Cortex (GO:0005938) Clathrin Vesicle Coat (GO:0030125) Clathrin-Coated Pit (GO:0005905) Clathrin-Coated Vesicle (GO:0030136) Endosome (GO:0005768) Extrinsic Component Of Plasma Membrane (GO:0019897) Nucleus (GO:0005634) Perinuclear Region Of Cytoplasm (GO:0048471) Plasma Membrane (GO:0005886)

Biology & Function

Description

Assigned Ontology terms

Biological Process	Endocytosis (GO:0006897)
Molecular Function	Clathrin Binding (GO:0030276) EH Domain Binding (GO:1990175) Phospholipid Binding (GO:0005543)

Cross-References

Database	Links
UNIPROT	Q4V882
Pfam	PF01417
PROSITE	PS50942 PS50330

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