NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Solute carrier family 2, facilitated glucose transporter member 12 - Bos taurus - NucEnvDB

Solute carrier family 2, facilitated glucose transporter member 12 (Bos taurus)

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Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Solute carrier family 2, facilitated glucose transporter member 12
Accession Code	Q5J316
Gene	SLC2A12
Organism	Bos taurus \| Cattle (Taxonomy: 9913)
Part of Reference Proteome?	Yes
Sequence (Length: 621)
MVPVENAEGPSLLKPKGRAAETDGSDRASGGPHPPWARGCGMYTLLSSVTAAVSGFLVGYELGIISGALLQIRTLLVLTCHEQEMVVSSLLIGALLASLIGGVLIDRYGRRAAIILSSCLLGLGSLVLII SLSYTTLIGGRIAIGVFISLSSTATCVYIAEIAPQHRRGLLVSLNELMIVIGILFAYISNYAFANISHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGHEEAASKVLGKLRAVLDTTEELTVIKSS LKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDQVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTSICRNHSPINQSL DESVFYGPGNLSASNDTLRESFKGMTFHSRSSLRPTRNDINGRGETTLASLPNAGLSQTEYQIVTDSADVPTFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISL TFLTVTDLIGLPWVCFIYTVMSLASLVFVIVFIPETKGCSLEQISVELAKENYVKNNICFMSHHREELVPKQLQKRKPQEQFLESKKLRGKGQPRQLSSEV

Subcellular Location

Description
Cell membrane {By SimilarityUniProtKB:Q8BFW9}; Multi-pass membrane protein {Sequence Analysis}. Endomembrane system {Experimental EvidencePubMed:16284803}; Multi-pass membrane protein {Sequence Analysis}. Cytoplasm, perinuclear region {ECO:0000250\|UniProtKB:Q8TD20}. Note=Localizes primarily perinuclear region in the absence of insulin. {ECO:0000250\|UniProtKB:Q8TD20}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Transmembrane	UniProt	Sequence Analysis {ECO:0000255}
Assigned Ontology terms

Cellular Component	Endomembrane System (GO:0012505) Perinuclear Region Of Cytoplasm (GO:0048471) Plasma Membrane (GO:0005886)

Biology & Function

Description
Insulin-independent facilitative glucose transporter. {By SimilarityUniProtKB:Q8BFW9}.
Assigned Ontology terms

Biological Process	Carbohydrate Transport (GO:0008643)
Molecular Function	Transmembrane Transporter Activity (GO:0022857)

Cross-References

Database	Links
UNIPROT	Q5J316
Pfam	PF00083
PROSITE	PS50850 PS00216

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