NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Prostate tumor-overexpressed gene 1 protein homolog - Rattus norvegicus - NucEnvDB

Prostate tumor-overexpressed gene 1 protein homolog (Rattus norvegicus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Prostate tumor-overexpressed gene 1 protein homolog
Accession Code	Q5U2W6
Gene	Ptov1
Organism	Rattus norvegicus \| Norway rat (Taxonomy: 10116)
Part of Reference Proteome?	Yes
Sequence (Length: 416)
MVRPRRAPHRSGAGGPLGGRGRPPRPLVVRAVRSRSWPAGPRGPQPPRIRARSAPPMEGARVFGALGPIGPSSPGLTLGGLAVNEHRLSNKLLAWSGVLEWQEKRRPFSDSAAKLKRTLPCQAYVNQGEN LETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNAIRQVITTRKQAVGPGGVHSGPVQIVNNKFLAW SGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTDQWPRRLFMQLIPQQLLTTLVPLFRNSRLVQFHFTKDMETLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQSNFVNGI RRVIANQQQVLQRSLEQEQQQRGMGG

Subcellular Location

Description
Cytoplasm {By SimilarityUniProtKB:Q86YD1}. Nucleus {By SimilarityUniProtKB:Q86YD1}. Cell membrane {By SimilarityUniProtKB:Q86YD1}. Cytoplasm, perinuclear region {By SimilarityUniProtKB:Q86YD1}. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts. {By SimilarityUniProtKB:Q86YD1}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Nucleoplasm (GO:0005654) Perinuclear Region Of Cytoplasm (GO:0048471) Plasma Membrane (GO:0005886) Transcription Regulator Complex (GO:0005667)

Biology & Function

Description
May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation. {By SimilarityUniProtKB:Q86YD1}.
Assigned Ontology terms

Biological Process	Positive Regulation Of Transcription By RNA Polymerase II (GO:0045944)
Molecular Function

Cross-References

Database	Links
UNIPROT	Q5U2W6
Pfam	PF11232

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