NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Membrane protein MLC1 - Macaca fascicularis - NucEnvDB

Membrane protein MLC1 (Macaca fascicularis)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Membrane protein MLC1
Accession Code	Q60HE7
Gene	MLC1
Organism	Macaca fascicularis \| Crab-eating macaque (Taxonomy: 9541)
Part of Reference Proteome?	Yes
Sequence (Length: 377)
MTQEPFREELAYDRMPTLERGRQDPASYAPDTKPSDLQLSKRLPPCFSPKTWVFSVLMGSCLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFAVTTTCLIWFG CKLILNPSAININFNLILLLLLELLMAATVIMSARSSEEYCKKKKGSMSDGTNILGEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACFPSAIASHVTAECPSKCLVEV LIAISSLTSPLLFTASGYLSFSVMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQSGPQERLAGEVARSPLKEFDKEKAWRAVVVQMAQ

Subcellular Location

Description
Membrane {Curator Inference}; Multi-pass membrane protein {Curator Inference}. Cell membrane {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Transmembrane	UniProt	Sequence Analysis {ECO:0000255}
Assigned Ontology terms

Cellular Component	Basolateral Plasma Membrane (GO:0016323) Caveola (GO:0005901) Cytoplasm (GO:0005737) Cytoplasmic Vesicle (GO:0031410) Early Endosome (GO:0005769) Endoplasmic Reticulum (GO:0005783) Endosome (GO:0005768) Lysosome (GO:0005764) Membrane Raft (GO:0045121) Perinuclear Region Of Cytoplasm (GO:0048471) Plasma Membrane (GO:0005886) Recycling Endosome (GO:0055037)

Biology & Function

Description
Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. {By Similarity}.
Assigned Ontology terms

Biological Process	Caveolin-Mediated Endocytosis (GO:0072584) Cellular Response To Cholesterol (GO:0071397) Ion Transport (GO:0006811) Positive Regulation Of Intracellular Transport (GO:0032388) Vesicle-Mediated Transport (GO:0016192)
Molecular Function	Identical Protein Binding (GO:0042802) Protein-Containing Complex Binding (GO:0044877)

Cross-References

Database	Links
UNIPROT	Q60HE7

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