NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

WD repeat-containing protein 44 - Mus musculus - NucEnvDB

WD repeat-containing protein 44 (Mus musculus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	WD repeat-containing protein 44
Accession Code	Q6NVE8
Gene	Wdr44
Organism	Mus musculus \| House mouse (Taxonomy: 10090)
Part of Reference Proteome?	Yes
Sequence (Length: 915)
MASESDTEEFYDAPEDVHLGTGYPVGSPGKVGLLSFKEAENTANQAGNESPVQELRQDVSKKIIESIIEESQKVLQLEDDSLDSKGKGLSDEATAGPSVAGTEFSNIPGLLAIEHELQQDSEKAESQNVA EESELETQKCFPSDETCEKSEKTVDETDNLTEVSSGEQLDASGLEAETLNKEALEVKEGDVLDPASLDTLSTTDFAAVEEVAPAKPPRHLTPEPDIVASTKKPVPARPPPPTNFPPPRPPPPSRPAPPPR KKKSELEFEALKTPDLDVPKENITSDSLLTTNMASENTVRDSLPSLDLASATSGDKIVTAQENGKAPDVQTVAGEVMGPQRPRSNSGRELTDEEILASVMIKNLDTGEEIPLSLAEEKLPTGINPLTLHI MRRTKEYVSNDATQSDDEEKLQSQQTDTDGGRLKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMK FSHCGRLLASAGQDNIVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDMGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHID FVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSM KYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKLEGIDKYEDAEVLDSTSTGIVKTDNTEVLLSADFTGAIKVFINK RKTVS

Subcellular Location

Description
Cytoplasm, cytosol. Cytoplasm, perinuclear region. Endosome membrane. Golgi apparatus, trans-Golgi network. Note=Colocalized with RAB11 along microtubules oriented toward lamellipodia. {By Similarity}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Cytosol (GO:0005829) Endosome Membrane (GO:0010008) Golgi Apparatus (GO:0005794) Microtubule (GO:0005874) Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
Downstream effector for RAB11. May be involved in vesicle recycling (By similarity). {By Similarity}.
Assigned Ontology terms

Biological Process	Regulation Of Cell Migration (GO:0030334)
Molecular Function	Small GTPase Binding (GO:0031267)

Cross-References

Database	Links
UNIPROT	Q6NVE8 Q3UT13 Q8BTS1
Pfam	PF00400
PROSITE	PS50082 PS50294

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