NucEnvDB
NucEnvDB
A database of Nuclear Envelope Proteins and their Interactions
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Twinfilin-2-A - Xenopus laevis - NucEnvDB
Twinfilin-2-A (
Xenopus laevis
)
FASTA
TEXT
XML
Subcellular Location
Biology & Function
Cross-References
General Information
Protein Information
Protein Name
Twinfilin-2-A
Accession Code
Q7ZXP0
Gene
twf2
Organism
Xenopus laevis
| African clawed frog (Taxonomy:
8355
)
Part of Reference Proteome?
Yes
Sequence (Length: 349)
Show
MAHQTGIHATPELKEFFAKARNGSIRLIKVVIEEEQLVLGSHKELKHAWEQDYDALIVPLLDESQPCYILYRLDSQNAQGYEWIFLSWSPDHSPVRLKMLYAATRATVKKEFGGGHIKDEIFGTLKEDVA
LSGYKKHVSLCAAPAPLTAAERELQEIKINEVKTEISVESKQQTLQGLSFPLRPEAEEAILLLKQKKINYIQLRLDLEKETVDLVHTKHTEIKDLPGRIPQDTARYHFFLYKHSHEGDHLESVVFIYSMP
GYKCSIKERMLYSSCKNRLLDSVEQDFQLEIAKKIEIEDGAELTDEFLYDEVHPKQHAFKQAFAKPKGPAGKRGQKRLIKGPGENGEDS
Subcellular Location
Description
Show
Cytoplasm, cytoskeleton {
By Similarity
}. Cytoplasm, perinuclear region {
By Similarity
}. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization. {
By Similarity
}.
Position in the Nuclear Envelope
Location
Location ID
Description
Perinuclear Region
SL-0198
The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology
Source
Annotation Type
Unknown
UniProt
Sequence Analysis
Assigned Ontology terms
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Cellular Component
Cytoskeleton
(
GO:0005856
)
Perinuclear Region Of Cytoplasm
(
GO:0048471
)
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Biology & Function
Description
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Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin (By similarity). {
By Similarity
}.
Assigned Ontology terms
Show
Biological Process
Negative Regulation Of Actin Filament Polymerization
(
GO:0030837
)
Molecular Function
Actin Binding
(
GO:0003779
)
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Cross-References
Database
Links
UNIPROT
Q7ZXP0
Pfam
PF00241
PROSITE
PS51263
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National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory