NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Gametogenetin - Mus musculus - NucEnvDB

Gametogenetin (Mus musculus)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	Gametogenetin
Accession Code	Q80WJ1
Gene	Ggn
Organism	Mus musculus \| House mouse (Taxonomy: 10090)
Part of Reference Proteome?	Yes
Sequence (Length: 673)
MGNVQSEPSAGGGSRKEQASDRASDSRRTPLVEPEVTPSSPAMRLARGLGVWFPGSSGPPGLLIPPEPQASSSPLPLTLELPSPVTPPPEEAAAVSTPPPPPVGTLLPAPSKWRKPTGTSVPRIRGLLEA SHRGQGDPPSLRPLPPLPRQLTEKDPVLRAPAPPPTPLEPRKQLPPAPSTCDPQPLSRRITLASSATSPTESQVRHSSEGQAAGGAHGGVPPQAGEGEMARSATSESGLSLLCKVTFKSGPHLSPTSASG PLAAKASPGAGGGGLFASSGAISYAEVLKQGPQPPGATRPLGEVPPGATRPLGEVPRAAQETEGGDGDGEGCSGPPSVPAPLARALPPPPYTTFPGSKPKFDWVSPPDGTERHFRFNGAVGGIGAPRRRT TTLSGPWGSPPPRSGQTHPSSGPRRPTPALLAPPMFIFPAPNNGEPVRPVPPSPQQIPPLPPPPPTPPATPPPAPPPTPQPPALPRTPILVARPPTPGPGHLESALAPTPPSTLSPTAAADQVPAATPAT VTSQVPATATAELSPPMPQPKTRTRRNKGPRAARGVIREEGTSGDGPREPNTAPVTDSSSGGGGGGSNGTSTAGASNKGTARHWPPFEVLNSCPCKCYCRHQRRHRRLPRNVSAWLSTPTNHLSEPPWVA TVKLAGSLVAGLEHYDLQATHST

Subcellular Location

Description
[Isoform 1]: Cytoplasm, perinuclear region. Note=Localizes along the nuclear membrane. [Isoform 2]: Cytoplasmic vesicle. [Isoform 3]: Nucleus, nucleolus.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Cytoplasmic Vesicle (GO:0031410) Nuclear Envelope (GO:0005635) Nucleolus (GO:0005730) Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
May be involved in spermatogenesis. {Experimental EvidencePubMed:12574169}.
Assigned Ontology terms

Biological Process	Cell Differentiation (GO:0030154) Double-Strand Break Repair (GO:0006302) Embryo Implantation (GO:0007566) Gamete Generation (GO:0007276) Protein Localization (GO:0008104) Protein-Containing Complex Assembly (GO:0065003) Spermatogenesis (GO:0007283)
Molecular Function	Identical Protein Binding (GO:0042802) Ubiquitin Protein Ligase Binding (GO:0031625)

Protein-Protein Interactions

Interactions with other proteins (3 interactors)

Partner (UniProt)		IntAct	Confidence score
Q5SV77	Gametogenetin-binding protein 2 (Dioxin-inducible factor 3) (DIF-3) (Protein ZNF403)	EBI-4370065	0.54
Q9R109	Ornithine decarboxylase antizyme 3 (AZ3) (ODC-Az 3) (OAZ-t)	EBI-4370118	0.54
Q6K1E7	Gametogenetin-binding protein 1	EBI-3890501	0.44

Cross-References

Database	Links
UNIPROT	Q80WJ1 Q5EBP4 Q80WI9 Q80WJ0
Pfam	PF15685

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