NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Palmitoyltransferase ZDHHC19 - Mus musculus - NucEnvDB

Palmitoyltransferase ZDHHC19 (Mus musculus)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	Palmitoyltransferase ZDHHC19
Accession Code	Q810M5
Gene	Zdhhc19
Organism	Mus musculus \| House mouse (Taxonomy: 10090)
Part of Reference Proteome?	Yes
Sequence (Length: 347)
MPFLKDAVTLVKEPQQLPSIPLSWFPSSVFAAFNVTLLLFLSGLFFGFPCRWLVQNGEWAFPAITGPLFILTFFSLVSLNFSDPGILHRGSTKEDPMTVHVVRVNQRAFRLEWCPKCLFHRPPRTYHCPW CNICVEDFDHHCKWVNNCIGHRNFRLFMLLVLSLCLYSGALLVTCLTFLFRTRHLPFSLDKGMAILVAVPAAGFLIPLFLLLLIQALSVSRAESSYESKCRYHPEYNPFDQGFAKNWYLAMFAPLGPNYM SEVVCLQRPVGTAWIQEKTKPSPPRRPKHCRPGPPGPQHQPRRVPGKGPPGSGEAAALQEMRRLPASVEKSPGGPRQPTAEPAAGDP

Subcellular Location

Description
Golgi apparatus membrane {By SimilarityUniProtKB:Q8WVZ1}; Multi-pass membrane protein {Sequence Analysis}. Cytoplasm, perinuclear region {By SimilarityUniProtKB:Q8WVZ1}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Transmembrane	UniProt	Sequence Analysis {ECO:0000255}
Assigned Ontology terms

Cellular Component	Endoplasmic Reticulum (GO:0005783) Golgi Apparatus (GO:0005794) Golgi Membrane (GO:0000139) Perinuclear Region Of Cytoplasm (GO:0048471) Perinucleolar Compartment (GO:0097356)

Biology & Function

Description
Palmitoyltransferase that mediates palmitoylation of RRAS, leading to increased cell viability. {By SimilarityUniProtKB:Q8WVZ1}.
Assigned Ontology terms

Biological Process	Peptidyl-L-Cysteine S-Palmitoylation (GO:0018230) Protein Targeting To Membrane (GO:0006612)
Molecular Function	Protein-Cysteine S-Palmitoyltransferase Activity (GO:0019706)

Protein-Protein Interactions

Interactions with other proteins (2 interactors)

Partner (UniProt)		IntAct	Confidence score
P40763	Signal transducer and activator of transcription 3 (Acute-phase response factor)	EBI-22117867	0.58
P62993	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)	EBI-22118041	0.50

Cross-References

Database	Links
UNIPROT	Q810M5
Pfam	PF01529
PROSITE	PS50216

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