NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Guanine nucleotide-binding protein subunit alpha-1 - Trichomonas vaginalis - NucEnvDB

Guanine nucleotide-binding protein subunit alpha-1 (Trichomonas vaginalis)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Guanine nucleotide-binding protein subunit alpha-1
Accession Code	Q86D96
Gene	GA1
Organism	Trichomonas vaginalis (Taxonomy: 5722)
Part of Reference Proteome?	No
Sequence (Length: 402)
MGCSASKPSEPSNAKLPSAPVPKKVEQVPEPKPEPQPQPEPQPQPEPPKPAEPAPAPAPAPEPQKPAEPAPKVVAVEDDTNEAYGLLLCGAGESGKTTFTRQLKLRYLNGFNEKDCRDFLRTIRGNLVET MQLLLVWLEHNNIEIEDSELSSMAQDIIDVDPQDCEFNEELVEKLKALWENEQIKKAFEHKDETAVPDHMPYFFAKIDELAGEDYIPSNEDVLRARIRSIGIEAITFDLQGARIRIFDVGGQKSERSKWA NVMNQVEGVIFCVSFAEFDKPMFEDQNVLRINDSLEIFGNITHQEKFSNSPIFLVCNKFDVFTEKIKNTDAFVKIFPEFSGDSHNPEACADYLIQRFLDKAAPLSEDRPIIQYKIVALNGDQVVETADAI CKFISDKYYQDA

Subcellular Location

Description
Cytoplasm. Cytoplasm, perinuclear region. Endomembrane system; Lipid-anchor. Note=Predominantly perinuclear.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Lipid-Anchored	UniProt	Sequence Analysis {ECO:0000255}
Assigned Ontology terms

Cellular Component	Endomembrane System (GO:0012505) Membrane (GO:0016020) Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. {By Similarity}.
Assigned Ontology terms

Biological Process	G Protein-Coupled Receptor Signaling Pathway (GO:0007186)
Molecular Function	G-Protein Beta/Gamma-Subunit Complex Binding (GO:0031683) GTP Binding (GO:0005525) GTPase Activity (GO:0003924)

Cross-References

Database	Links
UNIPROT	Q86D96
Pfam	PF00503
PROSITE	PS51882

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