NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Elongation factor 1-alpha 4 - Arabidopsis thaliana - NucEnvDB

Elongation factor 1-alpha 4 (Arabidopsis thaliana)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	Elongation factor 1-alpha 4
Accession Code	Q8GTY0
Gene	A4
Organism	Arabidopsis thaliana \| Thale cress (Taxonomy: 3702)
Part of Reference Proteome?	Yes
Sequence (Length: 449)
MGKEKFHINIVVIGHVDSGKSTTTGHLIYKLGGIDKRVIERFEKEAAEMNKRSFKYAWVLDKLKAERERGITIDIALWKFETTKYYCTVIDAPGHRDFIKNMITGTSQADCAVLIIDSTTGGFEAGISKD GQTREHALLAFTLGVKQMICCCNKMDATTPKYSKARYDEIIKEVSSYLKKVGYNPDKIPFVPISGFEGDNMIERSTNLDWYKGPTLLEALDQINEPKRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGMI KPGMVVTFAPTGLTTEVKSVEMHHESLLEALPGDNVGFNVKNVAVKDLKRGYVASNSKDDPAKGAANFTSQVIIMNHPGQIGNGYAPVLDCHTSHIAVKFSEILTKIDRRSGKEIEKEPKFLKNGDAGMV KMTPTKPMVVETFSEYPPLGRFAVRDMRQTVAVGVIKSVDKKDPTGAKVTKAAVKKGAK

Subcellular Location

Description
Cytoplasm {Experimental EvidencePubMed:21245040}. Cytoplasm, perinuclear region {Experimental EvidencePubMed:21245040}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Cytoplasm (GO:0005737) Mitochondrion (GO:0005739) Nucleus (GO:0005634) Perinuclear Region Of Cytoplasm (GO:0048471) Plant-Type Vacuole (GO:0000325) Plasma Membrane (GO:0005886) Plasmodesma (GO:0009506)

Biology & Function

Description
This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
Assigned Ontology terms

Biological Process	Translation (GO:0006412) Translational Elongation (GO:0006414)
Molecular Function	GTP Binding (GO:0005525) GTPase Activity (GO:0003924) MRNA Binding (GO:0003729) Translation Elongation Factor Activity (GO:0003746)

Protein-Protein Interactions

Interactions with other proteins (1 interactors)

Partner (UniProt)		IntAct	Confidence score
Q03250	Glycine-rich RNA-binding protein 7 (AtGR-RBP7) (AtRBG7) (Glycine-rich protein 7) (AtGRP7) (Protein COLD, CIRCADIAN RHYTHM, AND RNA BINDING 2) (Protein CCR2) (Small RNA binding protein 1) (AtSRBP1)	EBI-8801785	0.35

Cross-References

Database	Links
UNIPROT	Q8GTY0 P13905 Q0WSD5 Q39093 Q9C5L4
Pfam	PF00009 PF03144 PF03143
PROSITE	PS00301 PS51722

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