NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Exocyst complex component 1 - Mus musculus - NucEnvDB

Exocyst complex component 1 (Mus musculus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Exocyst complex component 1
Accession Code	Q8R3S6
Gene	Exoc1
Organism	Mus musculus \| House mouse (Taxonomy: 10090)
Part of Reference Proteome?	Yes
Sequence (Length: 894)
MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDKGDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKVYKWVASSTAEKNAFISCIWKLNQRYLRKKIDFV NVSSQLLEESVPSGENQSVAGGDEEAVDEYQELNAREEQDIEIMMEGCECAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNTLMQLLDEALTEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIH LSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLVSSRGIEACTNAADALLQCMNVALRPGHDMLLAVKQQQQRFSDLREHFARRLASHLNNVFVQQGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAK LMEWLKSTDYGKYEGLTKNYMDYLSRLYEREIKDFFEVAKMKMTGTSKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGSRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLS ELEPLCLAEQDFISKFFKLQQHQNMSASMTEAEDLDGGSLLRQHSSGTLLPVSSEKDMIRQMMIKIFRCIEPELNNLIALGDKVDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKC ISNQIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFINVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNH FFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEENLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH

Subcellular Location

Description
Midbody, Midbody ring {By SimilarityUniProtKB:Q9NV70}. Cytoplasm {By SimilarityUniProtKB:Q9NV70}. Cytoplasm, perinuclear region {By SimilarityUniProtKB:Q9NV70}. Cell membrane {By SimilarityUniProtKB:Q9NV70}. Note=Colocalizes with CNTRL/centriolin at the midbody ring. Localizes in cell membrane in the presence of SLC6A9. {By SimilarityUniProtKB:Q9NV70}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Cytoplasm (GO:0005737) Cytoplasmic Side Of Apical Plasma Membrane (GO:0098592) Exocyst (GO:0000145) Flemming Body (GO:0090543) Plasma Membrane (GO:0005886)

Biology & Function

Description
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. {By Similarity}.
Assigned Ontology terms

Biological Process	Embryo Implantation (GO:0007566) Exocytosis (GO:0006887) Golgi To Plasma Membrane Transport (GO:0006893) Membrane Fission (GO:0090148) Mitotic Cytokinesis (GO:0000281) Phosphatidylinositol-Mediated Signaling (GO:0048015) Positive Regulation Of Protein Secretion (GO:0050714) Protein Transport (GO:0015031) Vesicle Docking Involved In Exocytosis (GO:0006904) Vesicle Tethering Involved In Exocytosis (GO:0090522)
Molecular Function	Phosphatidylinositol-4,5-Bisphosphate Binding (GO:0005546)

Cross-References

Database	Links
UNIPROT	Q8R3S6 E9QQ24
Pfam	PF15277 PF09763

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