NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Synaptosomal-associated protein 47 - Mus musculus - NucEnvDB

Synaptosomal-associated protein 47 (Mus musculus)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	Synaptosomal-associated protein 47
Accession Code	Q8R570
Gene	Snap47
Organism	Mus musculus \| House mouse (Taxonomy: 10090)
Part of Reference Proteome?	Yes
Sequence (Length: 413)
MSSDMRVHSWSCSYYLDLEKQWVSGKLTLTPHSLKFIVEKTEEVLVGLPLSSIIEIRKESSLFIFGAITVLEKGQTKHWFSSLQPSRNVVFNVIEHFWRELLLSQPGTAANIPSHVTRGQELIGLMANSQ KRMEDTAKDLQQQSEQLDSVLKGLEKMESDLDVADRLLTELETPSWWPFGSKFWKMPAEENLKEGVSSTCEPFGKEGVVITVPAIISERAESHSKLGKLTVLVSALEIYDSCSLLLHRFEKEDVDDIKVH SPYEVSIRQRFIGKPDVAYQLISAKMPEVIPILEVQFSSKIELLEDALVLRNKVFASSAERHAASRPKGCTPHRELPTGGQEGEQLQLQKNLPLFSEGEAQELTQILSKMKGLALDTEAELERQDAALDG ITVAVDRATLNVDKQNRRMRKLM

Subcellular Location

Description
Endomembrane system {Experimental EvidencePubMed:16621800}. Cytoplasm, perinuclear region {Experimental EvidencePubMed:16621800}. Note=Appears to be exclusively membrane- bound. In primary neurons, widely distributed in both cell bodies and neuronal processes.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Asymmetric Synapse (GO:0032279) BLOC-1 Complex (GO:0031083) Dendrite (GO:0030425) Glutamatergic Synapse (GO:0098978) Hippocampal Mossy Fiber To CA3 Synapse (GO:0098686) Membrane (GO:0016020) Neuronal Cell Body (GO:0043025) Perinuclear Region Of Cytoplasm (GO:0048471) Plasma Membrane (GO:0005886) Postsynaptic Density (GO:0014069) SNARE Complex (GO:0031201) Synaptic Vesicle Membrane (GO:0030672)

Biology & Function

Description
May play a role in intracellular membrane fusion. {Experimental EvidencePubMed:16621800}.
Assigned Ontology terms

Biological Process	Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane (GO:0098967) Exocytosis (GO:0006887) Long-Term Synaptic Potentiation (GO:0060291) Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane (GO:0031629) Synaptic Vesicle Priming (GO:0016082) Vesicle Fusion (GO:0006906) Vesicle-Mediated Transport In Synapse (GO:0099003)
Molecular Function	SNAP Receptor Activity (GO:0005484) Syntaxin Binding (GO:0019905)

Protein-Protein Interactions

Interactions with other proteins (1 interactors)

Partner (UniProt)		IntAct	Confidence score
P48039	Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)	EBI-11576452	0.35

Cross-References

Database	Links
UNIPROT	Q8R570 Q3UNK4 Q8BK87
PROSITE	PS50192

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