NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Solute carrier family 2, facilitated glucose transporter member 10 - Mus musculus - NucEnvDB

Solute carrier family 2, facilitated glucose transporter member 10 (Mus musculus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Solute carrier family 2, facilitated glucose transporter member 10
Accession Code	Q8VHD6
Gene	Slc2a10
Organism	Mus musculus \| House mouse (Taxonomy: 10090)
Part of Reference Proteome?	Yes
Sequence (Length: 536)
MGLRPAVLLLCASVSLLGGLTFGYELAVISGALLPLQLNFGLSCLEQELLVGSLLLGALLASLVGGFLIDCYGRRRAILGSNAVLLAGSLILGLASSLPWLLLGRLSVGFAISLSSMACCIYVSELVGPR QRGVLVSLYEVGITVGILFSYGLNYVLAGSPWGWRHMFGWAAAPALLQSLSLFLLPAGAEGTAAPKDLIPLQGRETSKPGLVKPQYSFLDLFRAQDGMWSRTVVGLGLVLFQQLTGQPNVLYYASTIFRS VGFHGGSSAVLASVGLGTVKVAATLVATGLVDRAGRRVLLLFGCALMALSVSGIGLVSFAVSLDSGPSCLATSNASQQVDLPGSSGLLVRSSLPPVLHTNGDQGQLVLSVTERPIHPVITASLGPVLNTA SPVPTSPILEHTLLCWSALVCMMVYVSAFSVGFGPVTWLVLSEIYPAEIRGRAFAFCSSFNWAANLFISLSFLDLIGAIGLAWTFLLYGLTAVLGLAFIYLLVPETKGQSLAEIEQQFQTSRFPLNFGHR QRIGIQYHRLDVSSAS

Subcellular Location

Description
Endomembrane system {By SimilarityUniProtKB:O95528}; Multi-pass membrane protein {Sequence Analysis}. Cytoplasm, perinuclear region {By SimilarityUniProtKB:O95528}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Transmembrane	UniProt	Sequence Analysis {ECO:0000255}
Assigned Ontology terms

Cellular Component	Cytosol (GO:0005829) Endomembrane System (GO:0012505) Membrane (GO:0016020) Perinuclear Region Of Cytoplasm (GO:0048471) Plasma Membrane (GO:0005886)

Biology & Function

Description
Facilitative glucose transporter required for the development of the cardiovascular system. {By SimilarityUniProtKB:O95528}.
Assigned Ontology terms

Biological Process	Artery Development (GO:0060840) Cell Redox Homeostasis (GO:0045454) Circulatory System Development (GO:0072359) Dehydroascorbic Acid Transport (GO:0070837) Embryonic Skeletal Joint Development (GO:0072498) Glucose Import Across Plasma Membrane (GO:0098708) Glucose Transmembrane Transport (GO:1904659) Negative Regulation Of Connective Tissue Growth Factor Production (GO:0032683) Negative Regulation Of Gene Expression (GO:0010629) Negative Regulation Of Integrin-Mediated Signaling Pathway (GO:2001045) Negative Regulation Of Proteoglycan Biosynthetic Process (GO:1902729) Negative Regulation Of SMAD Protein Signal Transduction (GO:0060392) Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway (GO:0030512) Positive Regulation Of Gene Expression (GO:0010628) Positive Regulation Of Proteoglycan Biosynthetic Process (GO:1902730) Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway (GO:0030511) Regulation Of Extracellular Matrix Organization (GO:1903053) Skin Development (GO:0043588) Transmembrane Transport (GO:0055085)
Molecular Function	D-Glucose Transmembrane Transporter Activity (GO:0055056) Dehydroascorbic Acid Transmembrane Transporter Activity (GO:0033300) Glucose Transmembrane Transporter Activity (GO:0005355) Symporter Activity (GO:0015293)

Cross-References

Database	Links
UNIPROT	Q8VHD6
Pfam	PF00083
PROSITE	PS50850 PS00216

Powered by W3.css | Privacy Notice

x

This website uses cookies to improve user experience. By using NucEnvDB you consent to all cookies in accordance with our privacy policy. OK