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NucEnvDB
A database of Nuclear Envelope Proteins and their Interactions
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Serine/threonine-protein kinase 33 - Mus musculus - NucEnvDB
Serine/threonine-protein kinase 33 (
Mus musculus
)
FASTA
TEXT
XML
Subcellular Location
Biology & Function
Cross-References
General Information
Protein Information
Protein Name
Serine/threonine-protein kinase 33
Accession Code
Q924X7
Gene
Stk33
Organism
Mus musculus
| House mouse (Taxonomy:
10090
)
Part of Reference Proteome?
Yes
Sequence (Length: 491)
Show
MADPSLNDNPTACPHCASSQAGLLCVCPAGKSPVLVVEMSQTSSIGSTEFFASQERKKERNTSRESSLKDLSIRTSNVERKPQAQWSRSNVTVGKIPHIRMDDGAGIEEFYTFGRILGQGSFGMVFEAID
KETGAKWAIKKVNKEKAGSSAMKLLEREVSILKTVNHQHIIHLEQVFESPQKMYLVMELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTD
FGLSVQKHGSRSEGMMQTTCGTPIYMAPEVINAHDYSQQCDIWSIGVIMFILLCGEPPFLANSEEKLYELIKKGELRFENPVWESVSDSAKNTLKQLMKVDPAHRITAKELLDNQWLTGNTLSSARPTNV
LEMMKEWKNNPESDEETNTDEETEQSAVYSPSANTAKQPTNAAKKPAAESVGMTSSNSSSSKLLSAESKAEPEKSSETVGHASVAKTTLKSTTLFRGKKRL
Subcellular Location
Description
Show
Cytoplasm, perinuclear region {
Experimental Evidence
PubMed:16176263
}.
Position in the Nuclear Envelope
Location
Location ID
Description
Perinuclear Region
SL-0198
The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology
Source
Annotation Type
Unknown
UniProt
Sequence Analysis
Assigned Ontology terms
Show
Cellular Component
Cytoplasm
(
GO:0005737
)
Nucleus
(
GO:0005634
)
Perinuclear Region Of Cytoplasm
(
GO:0048471
)
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Biology & Function
Description
Hide
Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic behavior of the intermediate filament cytoskeleton by phosphorylation of VIME. {
Experimental Evidence
PubMed:18811945
}.
Assigned Ontology terms
Show
Biological Process
Mitotic DNA Damage Checkpoint Signaling
(
GO:0044773
)
Protein Autophosphorylation
(
GO:0046777
)
Molecular Function
ATP Binding
(
GO:0005524
)
Protein Serine Kinase Activity
(
GO:0106310
)
Protein Serine/Threonine Kinase Activity
(
GO:0004674
)
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Cross-References
Database
Links
UNIPROT
Q924X7
Q4A1D4
Pfam
PF00069
PROSITE
PS00107
PS50011
PS00108
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National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory