NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Serum response factor-binding protein 1 - Mus musculus - NucEnvDB

Serum response factor-binding protein 1 (Mus musculus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Serum response factor-binding protein 1
Accession Code	Q9CZ91
Gene	Srfbp1
Organism	Mus musculus \| House mouse (Taxonomy: 10090)
Part of Reference Proteome?	Yes
Sequence (Length: 441)
MAADPLPPSAMVQPGTLNLNNEVVKMRKEVKRIRVLVIRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLEEIHAMKELKPDVVTKSALSDDINFEKTCKKPDSTATDRAVARLAGHPLLKKKIDVLKDAV QAFKDARQSAPAAESSESTSGEGRCKDIARSKDDARESQHPERTVVREQKAKDTNTAAKNAASGSKEKLAKTEQAPRAGTTPGSQGRPSGKGAGVNSEHQGAPAPGDSNQGKASTKTPEDSVCEPANNGV SEEEESEGEKEYFDDSTEERFYKQSSASEDSDSGDDFFIGKVRRTRKKESGVHSSAKELKPLPKVPSKTSTLETPWDVRNDKHRPIPEARKFESVFFHSLAGPKSSRRDPREQAPKNKAPDFPENEPPVK KQFTKSAYRGFESVKQTMQAPLHPSWEASRRRKEQQSKIAVFQGKKITFDD

Subcellular Location

Description
Cytoplasm, perinuclear region {Experimental EvidencePubMed:16647043}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	90S Preribosome (GO:0030686) Nucleus (GO:0005634) Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells. {Experimental EvidencePubMed:15492011, Experimental EvidencePubMed:16647043}.
Assigned Ontology terms

Biological Process	Maturation Of SSU-RRNA (GO:0030490)
Molecular Function

Cross-References

Database	Links
UNIPROT	Q9CZ91 Q3UGY0 Q3UMK2 Q3UR20 Q8R3W6 Q9CRL0
Pfam	PF09073

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