NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Serine hydrolase-like protein 2 - Homo sapiens - NucEnvDB

Serine hydrolase-like protein 2 (Homo sapiens)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	Serine hydrolase-like protein 2
Accession Code	Q9H4I8
Gene	SERHL2
Organism	Homo sapiens \| Human (Taxonomy: 9606)
Part of Reference Proteome?	Yes
Sequence (Length: 314)
MSENAAPGLISELKLAVPWGHIAAKAWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQTFVSEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLIL LDTPLFLLESDEMENLLTYKRRAIEHVLQVEASQEPSHVFSLKQLLQRLLKSNSHLSEECGELLLQRGTTKVATGLVLNRDQRLAWAENSIDFISRELCAHSIRKLQAHVLLIKAVHGYFDSRQNYSEKE SLSFMIDTMKSTLKEQFQFVEVPGNHCVHMSEPQHVASIISSFLQCTHMLPAQL

Subcellular Location

Description
Cytoplasm, perinuclear region {By Similarity}. Peroxisome {By Similarity}. Note=Concentrated in perinuclear vesicles. May be located in peroxisomes. {By Similarity}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Perinuclear Region Of Cytoplasm (GO:0048471) Peroxisome (GO:0005777)

Biology & Function

Description
Probable serine hydrolase. May be related to cell muscle hypertrophy.
Assigned Ontology terms

Biological Process
Molecular Function	Hydrolase Activity (GO:0016787)

Protein-Protein Interactions

Interactions with other proteins (6 interactors)

Partner (UniProt)		IntAct	Confidence score
Q8TDZ2	[F-actin]-monooxygenase MICAL1 (EC 1.14.13.225) (EC 1.6.3.1) (Molecule interacting with CasL protein 1) (MICAL-1) (NEDD9-interacting protein with calponin homology and LIM domains)	EBI-21881296	0.35
Q9Y6M4	Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)	EBI-21881296	0.35
Q9Y4D1	Disheveled-associated activator of morphogenesis 1	EBI-21881296	0.35
Q9NWQ8	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane adapter protein PAG) (Transmembrane phosphoprotein Cbp)	EBI-21881296	0.35
Q9HAV0	Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4)	EBI-21881296	0.35
Q05086	Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)	EBI-21881296	0.35

Cross-References

Database	Links
UNIPROT	Q9H4I8 B1AHE9 B1AHF0 Q0VDJ1 Q5H973 Q9BR29 Q9BR30 Q9Y3I9
Pfam	PF00561
OMIM	619045
DisGeNET	253190

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