NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Dexamethasone-induced Ras-related protein 1 - Rattus norvegicus - NucEnvDB

Dexamethasone-induced Ras-related protein 1 (Rattus norvegicus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Dexamethasone-induced Ras-related protein 1
Accession Code	Q9JKF8
Gene	Rasd1
Organism	Rattus norvegicus \| Norway rat (Taxonomy: 10116)
Part of Reference Proteome?	Yes
Sequence (Length: 280)
MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQILDTKSCLKN KTKENVDVPLVICGNKGDRDFYREVEQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGDHGDAFGILAPFARRPSVHSDLMY IREKTSVSSQAKDKERCVIS

Subcellular Location

Description
Cell membrane {Curator Inference}; Lipid-anchor {Curator Inference}; Cytoplasmic side {Curator Inference}. Cytoplasm, perinuclear region {ECO:0000269\|PubMed:18922798}. Nucleus {ECO:0000269\|PubMed:18922798}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Lipid-Anchored	UniProt	By Similarity {ECO:0000250}
Assigned Ontology terms

Cellular Component	Cytoplasm (GO:0005737) Nucleus (GO:0005634) Perinuclear Region Of Cytoplasm (GO:0048471) Plasma Membrane (GO:0005886) Sarcoplasmic Reticulum (GO:0016529)

Biology & Function

Description
Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65.
Assigned Ontology terms

Biological Process	Negative Regulation Of DNA-Templated Transcription (GO:0045892) Nitric Oxide Mediated Signal Transduction (GO:0007263) Signal Transduction (GO:0007165)
Molecular Function	G-Protein Beta-Subunit Binding (GO:0031681) GTP Binding (GO:0005525) GTPase Activity (GO:0003924)

Cross-References

Database	Links
UNIPROT	Q9JKF8 Q4KLL2
Pfam	PF00071
PROSITE	PS51421

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