NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Geranylgeranyl pyrophosphate synthase - Mus musculus - NucEnvDB

Geranylgeranyl pyrophosphate synthase (Mus musculus)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Geranylgeranyl pyrophosphate synthase
Accession Code	Q9WTN0
Gene	Ggps1
Organism	Mus musculus \| House mouse (Taxonomy: 10090)
Part of Reference Proteome?	Yes
Sequence (Length: 300)
MEKTKEKAERILLEPYRYLLQLPGKQVRSKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDSSKLRRGFPVAHSIYGVPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDI YWRDTYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLDTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVQYLEDVGSFAYT RHTLRELEAKAYKQIEACGGNPSLVALVKHLSKMFTEENK

Subcellular Location

Description
Cytoplasm {Curator Inference}. Cytoplasm, perinuclear region {By SimilarityUniProtKB:O95749}. Cytoplasm, myofibril, sarcomere, Z line {By SimilarityUniProtKB:O95749}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Cytoplasm (GO:0005737) Cytosol (GO:0005829) Nucleoplasm (GO:0005654) Perinuclear Region Of Cytoplasm (GO:0048471) Z Disc (GO:0030018)

Biology & Function

Description
Catalyzes the trans-addition of the three molecules of isopentenyl diphosphate (IPP) onto dimethylallyl pyrophosphate (DMAPP) to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. {By SimilarityUniProtKB:O95749}.
Assigned Ontology terms

Biological Process	Farnesyl Diphosphate Biosynthetic Process (GO:0045337) Geranyl Diphosphate Biosynthetic Process (GO:0033384) Geranylgeranyl Diphosphate Biosynthetic Process (GO:0033386) Isoprenoid Biosynthetic Process (GO:0008299) Isoprenoid Metabolic Process (GO:0006720)
Molecular Function	Dimethylallyltranstransferase Activity (GO:0004161) Farnesyltranstransferase Activity (GO:0004311) Geranyltranstransferase Activity (GO:0004337) Identical Protein Binding (GO:0042802) Metal Ion Binding (GO:0046872) Prenyltransferase Activity (GO:0004659)

Cross-References

Database	Links
UNIPROT	Q9WTN0
Pfam	PF00348
PROSITE	PS00723 PS00444

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