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NucEnvDB
A database of Nuclear Envelope Proteins and their Interactions
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Probable spastin homolog spas-1 - Caenorhabditis briggsae - NucEnvDB
Probable spastin homolog spas-1 (
Caenorhabditis briggsae
)
FASTA
TEXT
XML
Subcellular Location
Biology & Function
Cross-References
General Information
Protein Information
Protein Name
Probable spastin homolog spas-1
Accession Code
A8XV40
Gene
spas
Organism
Caenorhabditis briggsae
(Taxonomy:
6238
)
Part of Reference Proteome?
Yes
Sequence (Length: 542)
Show
MFAFSKAPAGCSTYERVTQKFQDGSNKLRAAIEMDELTKQNGTINEKLQTAELYKQARQMLKEANEFNIMDIPESKRSEVREKREKTLNLEKSAQDRLIKICNEVDPNMKRASTAADPCRAARITPRNTR
ATVPGDKKVSKVKQTEKAPHVCSRGDRCGAHQPPPEKKSTPLKPVNQIRTRVKENKNPIGVQQQVFSFILSCCMRRNCRRPHYLFPCMISLKMNYFKFQATLPNQLNTVNRSNLLKGVDKAIGERLLDEI
LDSTGVRMDDVAGCHSAKATLEEAVILPALNPNLFSGLRQPVKGILLFGPPGNGKTLLAKAVAGESKQMFFNISASSLTSKWVGDSEKTIRGLFQIARNGQPSIIFIDEIDSILCERSEKDAEVSRRMKT
EFLVQFDGATSSPDDRILVIGATNRPYELDDAVLRRFPKRIMLNLPDTEARKELITNTLKKHDMMDGLSSSDIRYIASNTSGFSNSDLVALCKEAAMVPVREIHRSKLSVTDGDKIRKIRASDFDTALRT
IRPSTSDRILSKLSDFSRNFGC
Subcellular Location
Description
Show
Cytoplasm, cytoskeleton {
By Similarity
}. Cytoplasm, perinuclear region {
By Similarity
}. Note=Localized to the perinuclear region of the cytoplasm in early embryos. Present in the cytoskeletal fraction. {
By Similarity
}.
Position in the Nuclear Envelope
Location
Location ID
Description
Perinuclear Region
SL-0198
The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology
Source
Annotation Type
Unknown
UniProt
Sequence Analysis
Assigned Ontology terms
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Cellular Component
Cytoplasm
(
GO:0005737
)
Microtubule
(
GO:0005874
)
Microtubule Cytoskeleton
(
GO:0015630
)
Perinuclear Region Of Cytoplasm
(
GO:0048471
)
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Biology & Function
Description
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Severs microtubules, probably in an ATP-dependent fashion. {
By Similarity
}.
Assigned Ontology terms
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Biological Process
Molecular Function
ATP Binding
(
GO:0005524
)
ATP Hydrolysis Activity
(
GO:0016887
)
Isomerase Activity
(
GO:0016853
)
Microtubule Severing ATPase Activity
(
GO:0008568
)
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Cross-References
Database
Links
UNIPROT
A8XV40
Pfam
PF00004
PF17862
PROSITE
PS00674
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National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory