NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

TSK-associating protein 1 - Arabidopsis thaliana - NucEnvDB

TSK-associating protein 1 (Arabidopsis thaliana)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	TSK-associating protein 1
Accession Code	F4ICX9
Gene	TSA1
Organism	Arabidopsis thaliana \| Thale cress (Taxonomy: 3702)
Part of Reference Proteome?	Yes
Sequence (Length: 759)
MEIYTMKTNFLVLALSLCILLSSFHEVSCQDDGSGLSNLDLIERDYQDSVNALQGKDDEDQSAKIQSENQNNTTVTDKNTISLSLSDESEVGSVSDESVGRSSLLDQIKLEFEAHHNSINQAGSDGVKAE SKDDDEELSAHRQKMLEEIEHEFEAASDSLKQLKTDDVNEGNDEEHSAKRQSLLEEIEREFEAATKELEQLKVNDFTGDKDDEEHSAKRKSMLEAIEREFEAAMEGIEALKVSDSTGSGDDEEQSAKRLS MLEEIEREFEAASKGLEQLRASDSTADNNEEEHAAKGQSLLEEIEREFEAATESLKQLQVDDSTEDKEHFTAAKRQSLLEEIEREFEAATKDLKQLNDFTEGSADDEQSAKRNKMLEDIEREFEAATIGL EQLKANDFSEGNNNEEQSAKRKSMLEEIEREFEAAIGGLKQIKVDDSRNLEEESAKRKIILEEMEREFEEAHSGINAKADKEESAKKQSGSAIPEVLGLGQSGGCSCSKQDEDSSIVIPTKYSIEDILSE ESAVQGTETSSLTASLTQLVENHRKEKESLLGHRVLTSPSIASSTSESSATSETVETLRAKLNELRGLTARELVTRKDFGQILITAASFEELSSAPISYISRLAKYRNVIKEGLEASERVHIAQVRAKML KEVATEKQTAVDTHFATAKKLAQEGDALFVKIFAIKKLLAKLEAEKESVDGKFKETVKELSHLLADASEAYEEYHGAVRKAKDEQAAEEFAKEATQSAEIIWVKFLSSL

Subcellular Location

Description
Endoplasmic reticulum lumen. Nucleus envelope {Experimental EvidencePubMed:15964904, Experimental EvidencePubMed:24348487}. Cytoplasm {Experimental EvidencePubMed:15964904, Experimental EvidencePubMed:24348487}. Note=In interphase, found in ER bodies and at the nuclear envelope (PubMed:24348487). During mitosis, concentrates in limited areas close to the ends of spindle microtubules ahead of separating chromatids (PubMed:15964904). {Experimental EvidencePubMed:15964904, Experimental EvidencePubMed:24348487}.
Position in the Nuclear Envelope
Location	Location ID	Description
Nuclear Envelope	SL-0178	The nuclear envelope is a membrane system which surrounds the nucleoplasm of eukaryotic cells. It is composed of the nuclear lamina, nuclear pore complexes and two nuclear membranes. The space between the two membranes is called the nuclear intermembrane space.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Chloroplast Thylakoid Membrane (GO:0009535) Endoplasmic Reticulum Lumen (GO:0005788) Nuclear Envelope (GO:0005635) Peroxisome (GO:0005777) Plant-Type Vacuole (GO:0000325) Secretory Vesicle (GO:0099503)

Biology & Function

Description
Involved in seedling development in the dark. May be involved, when interacting with TSK, in the organization of spindle microtubules and may participate, when interacting with GIP1, in structural links between the nuclear envelope and the cytoskeleton. {Experimental EvidencePubMed:22133685, Experimental EvidencePubMed:24348487}.
Assigned Ontology terms

Biological Process	Defense Response To Fungus (GO:0050832) Photomorphogenesis (GO:0009640)
Molecular Function	Calcium Ion Binding (GO:0005509)

Protein-Protein Interactions

Interactions with other proteins (1 interactors)

Partner (UniProt)		IntAct	Confidence score
Q9AT76	Agamous-like MADS-box protein AGL27 (MADS box FLC1-like nuclear protein) (Protein FLOWERING LOCUS M) (Protein MADS AFFECTING FLOWERING 1)	EBI-16074844	0.37

Cross-References

Database	Links
UNIPROT	F4ICX9 F4ICY0 Q94AE1 Q9C831

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