NucEnvDB
NucEnvDB
A database of Nuclear Envelope Proteins and their Interactions
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Ataxin-10 - Mus musculus - NucEnvDB
Ataxin-10 (
Mus musculus
)
FASTA
TEXT
XML
Subcellular Location
Biology & Function
Interactions
Cross-References
General Information
Protein Information
Protein Name
Ataxin-10
Accession Code
P28658
Gene
Atxn10
Organism
Mus musculus
| House mouse (Taxonomy:
10090
)
Part of Reference Proteome?
Yes
Sequence (Length: 475)
Show
MAAPRMPPSRLSGIMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSTHAVELACRDPSQVEHLASSLQLITECFRCLRNACIECSVNQNSIRNLDTIGVAVDLVLLFRELRVEQDSLLT
AFRCGLQFLGNVASRNEESQSIVWVHAFPELFMSCLNHPDKKIVAYCSMILFTSLNAERMKDLEENLNIAINVIEAHQKHPASEWPFLIISDHFLKSPELVEAMYGKLSNQERITLLDIVIAKLVGEEQL
TKDDISIFVRHAELIANSFMDQCRNVLKLTSEPHTEDKEALVTIRLLDVLCEMTSNTELLGYLQVFPGLMERVIDVLRVIHEVGKESTNIFSPSDSLKAEGDIEHMTEGFKSHLIRLIGNLCYKNKENQD
KVNELDGIPLILDSSNIDDNNPFMMQWVVYAVRNLTEDNSQNQDVIAKMEEQGLADASLLKKMGFEIEKSGDKLILKSNNDIPPP
Subcellular Location
Description
Show
Cytoplasm, perinuclear region {
By Similarity
}.
Position in the Nuclear Envelope
Location
Location ID
Description
Perinuclear Region
SL-0198
The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology
Source
Annotation Type
Unknown
UniProt
Sequence Analysis
Assigned Ontology terms
Show
Cellular Component
Cytoplasm
(
GO:0005737
)
Cytosol
(
GO:0005829
)
Dendrite
(
GO:0030425
)
Neuronal Cell Body
(
GO:0043025
)
Perinuclear Region Of Cytoplasm
(
GO:0048471
)
Plasma Membrane
(
GO:0005886
)
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Biology & Function
Description
Hide
Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. {
By Similarity
}.
Assigned Ontology terms
Show
Biological Process
Cilium Assembly
(
GO:0060271
)
Nervous System Development
(
GO:0007399
)
Neuron Projection Development
(
GO:0031175
)
Molecular Function
Enzyme Binding
(
GO:0019899
)
Identical Protein Binding
(
GO:0042802
)
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Protein-Protein Interactions
Interactions with other proteins (6 interactors)
Show
Partner (UniProt)
IntAct
Confidence score
Q8BP00
IQ calmodulin-binding motif-containing protein 1
EBI-4283417
0.50
Q8CG73
Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)
EBI-4284701
0.35
Q83B01
Ankyrin repeats (3 copies)
EBI-21287600
0.37
Q83A33
Fic family protein
EBI-21288114
0.37
Q83A11
F-box domain-containing protein
EBI-21288333
0.37
Q6P1J9
Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)
EBI-20729673
0.35
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Cross-References
Database
Links
UNIPROT
P28658
Q543S3
Q99LP5
Q9D1I1
Pfam
PF09759
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National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory