NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

ADP-ribosylation factor 5 - Rattus norvegicus - NucEnvDB

ADP-ribosylation factor 5 (Rattus norvegicus)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	ADP-ribosylation factor 5
Accession Code	P84083
Gene	Arf5
Organism	Rattus norvegicus \| Norway rat (Taxonomy: 10116)
Part of Reference Proteome?	Yes
Sequence (Length: 180)
MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDM PNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR

Subcellular Location

Description
Golgi apparatus {By SimilarityUniProtKB:P84084}. Cytoplasm, perinuclear region {By SimilarityUniProtKB:P84085}. Membrane {By SimilarityUniProtKB:P84085}; Lipid-anchor {By SimilarityUniProtKB:P84085}. Golgi apparatus, trans-Golgi network membrane {By SimilarityUniProtKB:P84084}; Lipid-anchor {By SimilarityUniProtKB:P84084}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Lipid-Anchored	UniProt	By Similarity {ECO:0000250\|UniProtKB:P84085}
Assigned Ontology terms

Cellular Component	Cytoplasm (GO:0005737) Golgi Apparatus (GO:0005794) Perinuclear Region Of Cytoplasm (GO:0048471) Plasma Membrane (GO:0005886)

Biology & Function

Description
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. {By SimilarityUniProtKB:P84084}.
Assigned Ontology terms

Biological Process	Intracellular Protein Transport (GO:0006886) Retrograde Vesicle-Mediated Transport, Golgi To Endoplasmic Reticulum (GO:0006890) Vesicle-Mediated Transport (GO:0016192)
Molecular Function	GTP Binding (GO:0005525) GTPase Activity (GO:0003924)

Protein-Protein Interactions

Interactions with Nuclear Envelope proteins (2 interactors)

Partner (NucEnvDB)		IntAct	Confidence score
P00533	Epidermal growth factor receptor	EBI-22241891	0.35
P19357	Solute carrier family 2, facilitated glucose transporter member 4	EBI-921030	0.35
Interactions with other proteins (1 interactors)

Partner (UniProt)		IntAct	Confidence score
P09619	Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)	EBI-22248078	0.35

Cross-References

Database	Links
UNIPROT	P84083 P26437
Pfam	PF00025
PROSITE	PS51417

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