NucEnvDB

NucEnvDB

A database of Nuclear Envelope Proteins and their Interactions

Exportin-1 - Dictyostelium discoideum - NucEnvDB

Exportin-1 (Dictyostelium discoideum)

FASTA TEXT XML

Subcellular Location Biology & Function Cross-References

General Information

Protein Information
Protein Name	Exportin-1
Accession Code	Q54EV7
Gene	xpo1
Organism	Dictyostelium discoideum (Taxonomy: 44689)
Part of Reference Proteome?	Yes
Sequence (Length: 1057)
MENILNFNEPLDINLLDQIVSVLYNPLSNKNDIKAAQMVLGKFQEHPDAWSKVDTILETSKIVQTKFIALVIMDSLIKYRWKSLPREQCEGIKNYIVSLIIRLSSDPQTSSREKLLVNKLNLVFVQILKQ EWTTNWSTFIPEIISSSKTNESLCENNMVILRLLSEEIFNFSEEQMTQTKIQTLKITFEKEFSLINDLCFYILENATRASLIKATLETLQRFLNWVPLHYIIEVNGGIAEPSKLVKLLLHKYFPEPLFRN STLKCLTEIGNLNLGNQQYDAVFIAIIDKFMNQIKFIKPDPSKIPQDYEDGDQGERSFIHTVSLFLTGFFKSHLKIMENSLNIPYLTLAHEILVNISNIDELELFKICLEYWNFLSSNLYSDIATFTTTL LSTPPRLQLYKSVLSKVRVVLIDHMAKPEEVIVVEDENGNIVRETTKDTDSLTLYESMRETLIFLTHLDSENTQHIMLEKLQTLISGREFTFQRLNTLCWAIGSISGAQNKEQEKRFLVTVIKDLLELCQ NKKGKDNKAVIASDIMYIVGQYPRFLKDHWKFLKTVVNKLFEFMHESHPGVQDMACDTFLKISKQCKRKFVVLQVEESQPFINELLNQLSTTIAHLEQSQIHTFYEAVGYMIASSSDAAFREKLVNKFME LPNHSWLQIMGAASVKVESLLTVEVARDILNLIKTNNRAAMSLENCYITQISKIYLDLLNVYRTYSDHISRNPNIYRETLGQAMRSVKKETLKLLETFIEKSSDKQVIYSNFLQPLLEAVLGDYRTNIPE TRDPEVLSLMTAIITSLKQLVHPEVPKILEAVFETTLSMITKNFEDYPYHRINFFNLIRAINSNAFTVFHNLHPQQFKLLIDCVVWAFKHTERNISETGLHILKELIENVSKNSDVANVFFKTYLVSLLN DILYILTDSFHKSGFALECDILRMMFQVVENGVVKIPLFDPQQANFPSNSEYVKEIVVTFLSASPNVSRPQIQAFVTRLFNLANINNNDFKSATRDFLITLKEWKSHENADLYSDEKNIEKALALKKQSM IPGMVRPNDVNLEMNDL

Subcellular Location

Description
Nucleus {By Similarity}. Cytoplasm, perinuclear region {By Similarity}. Note=Shuttles between the nucleus and the cytoplasm. {By Similarity}.
Position in the Nuclear Envelope
Location	Location ID	Description
Perinuclear Region	SL-0198	The perinuclear region is the cytoplasmic region just around the nucleus.
Membrane Topology
Topology	Source	Annotation Type
Unknown	UniProt	Sequence Analysis
Assigned Ontology terms

Cellular Component	Cytoplasm (GO:0005737) Nucleus (GO:0005634) Perinuclear Region Of Cytoplasm (GO:0048471)

Biology & Function

Description
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES).
Assigned Ontology terms

Biological Process	Protein Export From Nucleus (GO:0006611) Ribosomal Large Subunit Export From Nucleus (GO:0000055) Ribosomal Small Subunit Export From Nucleus (GO:0000056)
Molecular Function	Nuclear Export Signal Receptor Activity (GO:0005049) Small GTPase Binding (GO:0031267)

Cross-References

Database	Links
UNIPROT	Q54EV7
Pfam	PF08767 PF18777 PF18784 PF18787 PF03810 PF08389
PROSITE	PS50166

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