NucEnvDB
NucEnvDB
A database of Nuclear Envelope Proteins and their Interactions
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p8 - African swine fever virus BA71V - NucEnvDB
p8 (
African swine fever virus BA71V
)
FASTA
TEXT
XML
Subcellular Location
Biology & Function
Cross-References
General Information
Protein Information
Protein Name
p8
Accession Code
Q65179
Gene
CP530R
Organism
African swine fever virus BA71V
(Taxonomy:
10498
)
Part of Reference Proteome?
Yes
Sequence (Length: 530)
Show
MPSNMKQFCKISVWLQQHDPDLLEIINNLCMLGNLSAAKYKHGVTFIYPKQAKIRDEIKKHAYSNDPSQAIKTLESLILP
FYIPTPAEFTGEIGSYTGVKLEVEKTEANKVILKNGEAVLVPAADFKPFPDRRLAVWIMESGSMPLEGPPYKRKKEGGGN
DPPVPKHISPYTPRTRIAIEVEKAFDDCMRQNWCSVNNPYLAKSVSLLSFLSLNHPTEFIKVLPLIDFDPLVTFYLLLEP
YKTHGDDFLIPETILFGPTGWNGTDLYQSAMLEFKKFFTQITRQTFMDIADSATKEVDVPICYSDPETVHSYTNHVRTEI
LHHNAVNKVTTPNLVVQAYNELEQTNTIRHYGPIFPESTINALRFWKKLWQDEQRFVIHGLHRTLMDQPTYETSEFAEIV
RNLRFSRPGNNYINELNITSPAMYGDKHTTGDIAPNDRFAMLVAFINSTDFLYTAIPEEKVGGNETQTSSLTDLVPTRLH
SFLNHNLSKLKILNRAQQTVRNILSNDCLNQLKHYVKHTGKNEILKLLQE
Structure Viewer (PDB: 7BQA)
Select PDB ID
6LNL
6NLN
7BQ9
7BQA
7CP2
Subcellular Location
Description
Show
[Polyprotein pp62]: Host cytoplasm, host perinuclear region {
Experimental Evidence
PubMed:9223468
}. Note=Found in perinuclear cytoplasmic viral factories during assembly. {
Experimental Evidence
PubMed:9223468
}. [p35]: Virion {
Experimental Evidence
PubMed:30185597
,
Experimental Evidence
PubMed:33629764
}. Note=Located in the core shell, which functions like a matrix between the DNA and the inner envelope. {
Experimental Evidence
PubMed:33629764
}. [p15]: Virion {
Experimental Evidence
PubMed:30185597
,
Experimental Evidence
PubMed:33629764
}. Note=Located in the core shell, which functions like a matrix between the DNA and the inner envelope. {
Experimental Evidence
PubMed:33629764
}. [p8]: Virion {
Experimental Evidence
PubMed:30185597
}. Note=Located in the core shell, which functions like a matrix between the DNA and the inner envelope. {ECO:0000303|PubMed:30185597}.
Position in the Nuclear Envelope
Location
Location ID
Description
Host Perinuclear Region
SL-0382
The host perinuclear region is the host cytoplasmic region just around the host nucleus.
Note: This location is defined for viral proteins that appear in the perinuclear region of infected host cells
Membrane Topology
Topology
Source
Annotation Type
Unknown
UniProt
Sequence Analysis
Assigned Ontology terms
Show
Cellular Component
Host Cell Perinuclear Region Of Cytoplasm
(
GO:0044220
)
Virion Component
(
GO:0044423
)
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Biology & Function
Description
Hide
[Polyprotein pp62]: Essential for the correct assembly and maturation of the core of the virion. {
Experimental Evidence
PubMed:19846532
}. [p35]: Component of the core shell (PubMed:30185597). Binds to phosphatidylserine, which may enable the core shell binding with the inner membrane (PubMed:32519301). {
Experimental Evidence
PubMed:30185597
,
Experimental Evidence
PubMed:32519301
}. [p15]: Component of the core shell (PubMed:30185597). Binds to phosphatidylserine and DNA, which may link the core shell to the inner membrane and to the viral nucleoid (PubMed:32451720). {
Experimental Evidence
PubMed:30185597
, ECO:0000269|PubMed:32451720}. [p8]: Component of the core shell. {
Experimental Evidence
PubMed:30185597
}.
Assigned Ontology terms
Show
Biological Process
Viral Capsid Assembly
(
GO:0019069
)
Molecular Function
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Cross-References
Database
Links
UNIPROT
Q65179
Q86851
PDB
6LNL
6NLN
7BQ9
7BQA
7CP2
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