National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory
Protein Information |
|
|---|---|
| Protein Name | Transmembrane protein 18 |
| Accession Code | Q96B42 |
| Gene | TMEM18 |
| Organism | Homo sapiens | Human (Taxonomy: 9606) |
| Part of Reference Proteome? | Yes |
| Sequence (Length: 140) |
Description |
Position in the Nuclear Envelope |
|
|---|---|---|
| Location | Location ID | Description |
| Nuclear Envelope | SL-0178 | The nuclear envelope is a membrane system which surrounds the nucleoplasm of eukaryotic cells. It is composed of the nuclear lamina, nuclear pore complexes and two nuclear membranes. The space between the two membranes is called the nuclear intermembrane space. |
| Nuclear Membrane | SL-0182 | The membrane surrounding the nucleus. This term is used when it is not known if the protein is found in or associated with the inner or outer nuclear membrane. | Membrane Topology |
| Topology | Source | Annotation Type |
| Transmembrane | UniProt | Sequence Analysis {ECO:0000255} | Assigned Ontology terms |
Description |
|
|---|---|
| Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC). {Experimental EvidencePubMed:18559506, Experimental EvidencePubMed:21980424}. | Assigned Ontology terms |
Interactions with other proteins (2 interactors) |
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|---|---|---|---|
Database | Links |
| UNIPROT | Q96B42 D6W4X9 Q8N5H2 Q9NTH3 |
| Pfam | PF14770 |
| OMIM | 613220 |
| DisGeNET | 129787 |
National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory