National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory
Protein Information |
|
|---|---|
| Protein Name | Phosphatidylserine decarboxylase 2 alpha chain |
| Accession Code | Q9UTB5 |
| Gene | psd2 |
| Organism | Schizosaccharomyces pombe 972h- (Taxonomy: 284812) |
| Part of Reference Proteome? | Yes |
| Sequence (Length: 516) |
Description |
Position in the Nuclear Envelope |
|
|---|---|---|
| Location | Location ID | Description |
| Nuclear Envelope | SL-0178 | The nuclear envelope is a membrane system which surrounds the nucleoplasm of eukaryotic cells. It is composed of the nuclear lamina, nuclear pore complexes and two nuclear membranes. The space between the two membranes is called the nuclear intermembrane space. | Membrane Topology |
| Topology | Source | Annotation Type |
| Transmembrane | UniProt | Sequence Analysis {ECO:0000255|HAMAP-Rule:MF_03208} | Assigned Ontology terms |
Description |
|
|---|---|
| Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine (By similarity). Together with psd1 and psd3, responsible for the majority of phosphatidylethanolamine synthesis (PubMed:19286980). Plays a role in lipid droplet biogenesis at the endoplasmic reticulum membrane (PubMed:34818062). {Sequence AnalysisHAMAP-Rule:MF_03208, Experimental EvidencePubMed:19286980, Experimental EvidencePubMed:34818062}. | Assigned Ontology terms |
National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory