The nuclear envelope is a membrane system which surrounds the nucleoplasm of eukaryotic cells. It is composed of the nuclear lamina, nuclear pore complexes and two nuclear membranes. The space between the two membranes is called the nuclear intermembrane space.
The membrane surrounding the nucleus. This term is used when it is not known if the protein is found in or associated with the inner or outer nuclear membrane.
Component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton (By similarity). Plays a role in the nuclear positioning and links the nucleus to the microtubule organizing center (MTOC) (PubMed:10556085, PubMed:22927463, PubMed:15579692). Collaborates with Klar to promote even spacing of the myonuclei at the periphery of striated muscle fibers by mediating a tight association between a nuclear ring structure of Msp300 and the plus ends of a unique astral microtubule (MT) network (PubMed:22927463). {By
SimilarityUniProtKB:Q8WXH0, Experimental EvidencePubMed:10556085, Experimental EvidencePubMed:15579692, Experimental EvidencePubMed:22927463}.
National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory