Interactions with Nuclear Envelope proteins (9 interactors)
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Partner (NucEnvDB) IntAct Confidence score
O43542 DNA repair protein XRCC3 EBI-9249126 0.73
P63165 Small ubiquitin-related modifier 1 EBI-15819689 0.44
Q06609 Self EBI-297242 0.92
Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 EBI-9064676 0.37
P00519 Tyrosine-protein kinase ABL1 EBI-6995587 0.40
Q6PIW4 Fidgetin-like protein 1 EBI-21840775 0.35
Q9UPT6 C-Jun-amino-terminal kinase-interacting protein 3 EBI-9064650 0.37
Q9UBU9 Nuclear RNA export factor 1 EBI-3914918 0.37
O43502 DNA repair protein RAD51 homolog 3 EBI-7988560 0.66
Interactions with other proteins (124 interactors)
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Partner (UniProt) IntAct Confidence score
P51587 Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein) EBI-297231 0.98
P04637 Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53) EBI-367003 0.40
Q12873 Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH) EBI-729210 0.00
P08670 Vimentin EBI-730657 0.00
P43351 DNA repair protein RAD52 homolog EBI-706470 0.63
P94102 DNA repair protein RAD51 homolog 1 (Rad51-like protein 1) (AtRAD51) EBI-930862 0.37
Q7Y1C5 Protein BREAST CANCER SUSCEPTIBILITY 2 homolog A (AtBRCA2A) EBI-930894 0.37
Q7Y1C4 Protein BREAST CANCER SUSCEPTIBILITY 2 homolog B (AtBRCA2B) EBI-944276 0.37
P41214 Eukaryotic translation initiation factor 2D (eIF2d) (Hepatocellular carcinoma-associated antigen 56) (Ligatin) EBI-1081745 0.00
Q9Y376 Calcium-binding protein 39 (MO25alpha) (Protein Mo25) EBI-1082450 0.00
Q9Y5L4 Mitochondrial import inner membrane translocase subunit Tim13 EBI-1085852 0.00
P36601 DNA repair protein rhp51 (RAD51 homolog) EBI-1109552 0.55
Q96B01 RAD51-associated protein 1 (HsRAD51AP1) (RAD51-interacting protein) EBI-1178705 0.79
Q6UWZ7 BRCA1-A complex subunit Abraxas 1 (Coiled-coil domain-containing protein 98) (Protein FAM175A) EBI-1263592 0.27
Q96RL1 BRCA1-A complex subunit RAP80 (Receptor-associated protein 80) (Retinoid X receptor-interacting protein 110) (Ubiquitin interaction motif-containing protein 1) EBI-1263606 0.27
Q9BQ15 SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1) (hSSB1) EBI-2121557 0.46
Q9UI08 Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like) EBI-7203877 0.44
P60709 Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed] EBI-3646976 0.37
P07737 Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I) EBI-3646981 0.37
P27694 Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed] EBI-3647003 0.37
P15927 Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34) EBI-3647007 0.37
P35244 Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3) EBI-3647015 0.37
P16104 Histone H2AX (H2a/x) (Histone H2A.X) EBI-8589785 0.27
O60701 UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) EBI-3912761 0.37
O14757 Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1) EBI-4404023 0.52
Q6NVH7 ATPase SWSAP1 (SWIM-type zinc finger 7-associated protein 1) (SWS1-associated protein 1) (ZSWIM7-associated protein 1) (ZSWIM7AP1) EBI-5281993 0.52
Q86YC2 Partner and localizer of BRCA2 EBI-7615447 0.80
P38398 Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1) EBI-7615501 0.72
Q96PU4 E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2) EBI-6051513 0.40
Q9W157 Breast cancer type 2 susceptibility protein homolog (dmbrca2) EBI-7677194 0.35
Q9NTI5 Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor) (Androgen-induced prostate proliferative shutoff-associated protein AS3) EBI-7677915 0.35
P42574 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] EBI-6592054 0.27
P07900 Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38) EBI-9064637 0.37
Q8WX92 Negative elongation factor B (NELF-B) (Cofactor of BRCA1) EBI-9064611 0.37
P67870 Casein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a) EBI-9064624 0.37
P11172 Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (ODC) (OMPD) (EC 4.1.1.23) (OMPdecase)] EBI-9064689 0.37
Q9UHG2 ProSAAS (Proprotein convertase subtilisin/kexin type 1 inhibitor) (Proprotein convertase 1 inhibitor) (pro-SAAS) [Cleaved into: KEP; Big SAAS (b-SAAS); Little SAAS (l-SAAS) (N-proSAAS); Big PEN-LEN (b-PEN-LEN) (SAAS CT(1-49)); PEN; Little LEN (l-LEN); Big LEN (b-LEN) (SAAS CT(25-40))] EBI-9064663 0.37
Q14694 Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) EBI-9064702 0.37
P55290 Cadherin-13 (Heart cadherin) (H-cadherin) (P105) (Truncated cadherin) (T-cad) (T-cadherin) EBI-9070137 0.37
Q15828 Cystatin-M (Cystatin-6) (Cystatin-E) EBI-9070150 0.37
Q96KN1 Protein LRATD2 (Breast cancer membrane protein 101) (LRAT domain-containing 2) (Protein FAM84B) (Protein NSE2) EBI-9070163 0.54
Q13007 Interleukin-24 (IL-24) (Melanoma differentiation-associated gene 7 protein) (MDA-7) (Suppression of tumorigenicity 16 protein) EBI-9070176 0.51
Q86UX2 Inter-alpha-trypsin inhibitor heavy chain H5 (ITI heavy chain H5) (ITI-HC5) (Inter-alpha-inhibitor heavy chain 5) EBI-9070189 0.37
P11245 Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (N-acetyltransferase type 2) (NAT-2) (Polymorphic arylamine N-acetyltransferase) (PNAT) EBI-9070202 0.54
Q9Y5Y6 Suppressor of tumorigenicity 14 protein (EC 3.4.21.109) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease 14) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein) EBI-9070215 0.37
P04155 Trefoil factor 1 (Breast cancer estrogen-inducible protein) (PNR-2) (Polypeptide P1.A) (hP1.A) (Protein pS2) EBI-9070228 0.37
Q9BZ95 Histone-lysine N-methyltransferase NSD3 (EC 2.1.1.370) (EC 2.1.1.371) (Nuclear SET domain-containing protein 3) (Protein whistle) (WHSC1-like 1 isoform 9 with methyltransferase activity to lysine) (Wolf-Hirschhorn syndrome candidate 1-like protein 1) (WHSC1-like protein 1) EBI-9070241 0.54
Q8IUH5 Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Acyltransferase ZDHHC17) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 17) (DHHC17) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) EBI-9087924 0.37
Q9HAV2 Heat shock transcription factor 1 EBI-9368380 0.40
P58340 Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1) EBI-9368358 0.40
Q96BE0 Heat shock protein family A (Hsp70) member 8b EBI-9368402 0.40
A2AUM9 Centrosomal protein of 152 kDa (Cep152) EBI-10994361 0.35
Q9Z1B5 Mitotic spindle assembly checkpoint protein MAD2A (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1) EBI-10996176 0.35
A2APR8 Mitotic checkpoint serine/threonine-protein kinase BUB1 EBI-11001201 0.35
P60953 Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein) EBI-11002356 0.35
Q6P1J9 Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein) EBI-11014586 0.35
Q5FBB7 Shugoshin 1 (Serologically defined breast cancer antigen NY-BR-85) (Shugoshin-like 1) EBI-11015316 0.35
Q91X51 Golgi reassembly-stacking protein 1 (Golgi peripheral membrane protein p65) (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) EBI-11015786 0.35
Q9CWL8 Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) EBI-11023129 0.35
Q3U410 Kelch-like protein 21 EBI-11026005 0.35
D3YY91 Leucine-rich repeat protein 1 EBI-11028850 0.35
P78318 Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16) EBI-11039408 0.35
E9Q4K7 Kinesin family member 13B EBI-11042417 0.35
Q9UGU5 HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG) EBI-11042629 0.35
Q8VE37 Regulator of chromosome condensation (Chromosome condensation protein 1) EBI-11043815 0.35
P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform) (CNA beta) EBI-11047313 0.35
D6RA96 Regulator of telomere elongation helicase 1 (EC 3.6.4.12) EBI-11047357 0.35
Q8CIF6 SID1 transmembrane family member 2 EBI-11072478 0.35
D6RI17 M-phase phosphoprotein 9 EBI-11073846 0.35
Q9BSJ2 Gamma-tubulin complex component 2 (GCP-2) (hGCP2) (Gamma-ring complex protein 103 kDa) (h103p) (hGrip103) (Spindle pole body protein Spc97 homolog) (hSpc97) EBI-11083048 0.35
O08586 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog) EBI-11086220 0.35
Q9NP66 High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1) EBI-11087905 0.35
Q9H2H0 CXXC-type zinc finger protein 4 (Inhibition of the Dvl and axin complex protein) EBI-11088370 0.35
Q6DFZ1 Golgi-specific brefeldin A-resistance factor 1 EBI-11091172 0.35
Q8C8N2 Protein SCAI (Suppressor of cancer cell invasion protein) EBI-11092225 0.35
Q56A08 G-patch domain and KOW motifs-containing protein (Protein MOS2 homolog) EBI-11095792 0.35
Q8CAF4 NHS-like protein 1 EBI-11096313 0.35
P35749 Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC) EBI-11098041 0.35
Q6PJG2 Mitotic deacetylase-associated SANT domain protein (ELM2 and SANT domain-containing protein 1) EBI-11106137 0.35
P35700 Peroxiredoxin-1 (EC 1.11.1.24) (Macrophage 23 kDa stress protein) (Osteoblast-specific factor 3) (OSF-3) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1) EBI-11114197 0.35
O75792 Ribonuclease H2 subunit A (RNase H2 subunit A) (EC 3.1.26.4) (Aicardi-Goutieres syndrome 4 protein) (AGS4) (RNase H(35)) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A) EBI-11115131 0.35
P46467 Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6) (Suppressor of K(+) transport growth defect 1) (Protein SKD1) EBI-11115954 0.35
Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 (hNAF1) EBI-11116990 0.35
Q14114 Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) EBI-11117560 0.35
Q9CQW0 ER membrane protein complex subunit 6 (Transmembrane protein 93) EBI-11121111 0.35
P51148 Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L) EBI-11124397 0.35
Q9ET47 Espin (Ectoplasmic specialization protein) EBI-11124608 0.35
P70335 Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK) EBI-11124658 0.35
O00257 E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2) EBI-11125021 0.35
Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1) EBI-11127729 0.35
O00400 Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1) EBI-11135399 0.35
Q7Z4S6 Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62) EBI-11140402 0.35
Q9UBT6 DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP) EBI-11141739 0.35
P51530 DNA replication ATP-dependent helicase/nuclease DNA2 (hDNA2) (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)] EBI-21525688 0.35
Q14565 Meiotic recombination protein DMC1/LIM15 homolog EBI-21540407 0.35
Q96LI6 Heat shock transcription factor, Y-linked (Heat shock transcription factor 2-like protein) (HSF2-like) EBI-21542067 0.35
Q86XE0 Sorting nexin-32 (Sorting nexin-6B) EBI-21777996 0.35
P28347 Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13) EBI-21881702 0.40
Q14676 Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1) EBI-15557704 0.52
O94761 ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4) EBI-15710123 0.40
P54132 RecQ-like DNA helicase BLM (EC 3.6.4.12) (Bloom syndrome protein) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3) EBI-15819727 0.44
O94762 ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) EBI-15710184 0.35
Q14191 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 3.6.4.12)] EBI-15710258 0.40
P61956 Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B) EBI-15819708 0.44
O14980 Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) EBI-16073017 0.40
O75417 DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta) EBI-16141075 0.60
P14404 Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein homolog) EBI-21028244 0.35
Q92698 DNA repair and recombination protein RAD54-like (EC 3.6.4.12) (RAD54 homolog) (hHR54) (hRAD54) EBI-22014998 0.37
P0DOF2 Matrix protein (Phosphoprotein M2) EBI-25603126 0.35
P15924 Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) EBI-25483457 0.35
Q02413 Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen) EBI-25483457 0.35
P16403 Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1) EBI-25483457 0.35
P07477 Serine protease 1 (EC 3.4.21.4) (Anionic trypsin I) (Anionic trypsin-I) (Beta-trypsin) (Cationic trypsinogen) (Pretrypsinogen I) (Trypsin I) (Trypsin-1) [Cleaved into: Alpha-trypsin chain 1; Alpha-trypsin chain 2] EBI-25483457 0.35
Q96P63 Serpin B12 EBI-25483457 0.35
P81605 Dermcidin (EC 3.4.-.-) (Preproteolysin) [Cleaved into: Survival-promoting peptide; DCD-1] EBI-25483457 0.35
Q01469 Fatty acid-binding protein 5 (Epidermal-type fatty acid-binding protein) (E-FABP) (Fatty acid-binding protein, epidermal) (Psoriasis-associated fatty acid-binding protein homolog) (PA-FABP) EBI-25483457 0.35
P68363 Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain] EBI-25483457 0.35
P62899 60S ribosomal protein L31 (Large ribosomal subunit protein eL31) EBI-25483457 0.35
P62701 40S ribosomal protein S4, X isoform (SCR10) (Single copy abundant mRNA protein) (Small ribosomal subunit protein eS4) EBI-25483457 0.35
P39019 40S ribosomal protein S19 (Small ribosomal subunit protein eS19) EBI-25483457 0.35
P01040 Cystatin-A (Cystatin-AS) (Stefin-A) [Cleaved into: Cystatin-A, N-terminally processed] EBI-25483457 0.35
Q14159 DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair) EBI-26608253 0.66
Q9H9A7 RecQ-mediated genome instability protein 1 (BLM-associated protein of 75 kDa) (BLAP75) (FAAP75) EBI-26616811 0.35
Q00341 Vigilin (High density lipoprotein-binding protein) (HDL-binding protein) EBI-27122970 0.50
National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory