National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory
Protein Information |
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| Protein Name | GTP-binding nuclear protein Ran |
| Accession Code | P62826 |
| Gene | RAN |
| Organism | Homo sapiens | Human (Taxonomy: 9606) |
| Part of Reference Proteome? | Yes |
| Sequence (Length: 216) | |
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MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYY IQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKP FLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL |
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Structure Viewer (PDB: 5UWT) |
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Description |
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| GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs (PubMed:10400640, PubMed:8276887, PubMed:8896452, PubMed:8636225, PubMed:8692944, PubMed:9351834, PubMed:9428644, PubMed:9822603, PubMed:17209048, PubMed:26272610, PubMed:27306458). Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis (PubMed:7819259, PubMed:8896452, PubMed:8636225, PubMed:8692944, PubMed:9351834, PubMed:9428644, PubMed:9822603, PubMed:29040603, PubMed:11336674, PubMed:26272610). Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensures the directionality of the transport (PubMed:8896452, PubMed:9351834, PubMed:9428644). Interaction with RANBP1 induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (PubMed:20485264). RAN (GTP-bound form) triggers microtubule assembly at mitotic chromosomes and is required for normal mitotic spindle assembly and chromosome segregation (PubMed:10408446, PubMed:29040603). Required for normal progress through mitosis (PubMed:8421051, PubMed:12194828, PubMed:29040603). The complex with BIRC5/survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules (PubMed:18591255). Acts as a negative regulator of the kinase activity of VRK1 and VRK2 (PubMed:18617507). Enhances AR- mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases (PubMed:10400640). {Experimental EvidencePubMed:10400640, Experimental EvidencePubMed:10408446, Experimental EvidencePubMed:11336674, Experimental EvidencePubMed:12194828, Experimental EvidencePubMed:17209048, Experimental EvidencePubMed:18591255, Experimental EvidencePubMed:18617507, Experimental EvidencePubMed:20485264, Experimental EvidencePubMed:26272610, Experimental EvidencePubMed:27306458, Experimental EvidencePubMed:29040603, Experimental EvidencePubMed:7819259, Experimental EvidencePubMed:8276887, Experimental EvidencePubMed:8421051, Experimental EvidencePubMed:8636225, Experimental EvidencePubMed:8692944, Experimental EvidencePubMed:8896452, Experimental EvidencePubMed:9351834, Experimental EvidencePubMed:9428644, Experimental EvidencePubMed:9822603, Curator InferencePubMed:26272610}. | Assigned Ontology terms |
| Biological Process | Actin Cytoskeleton Organization (GO:0030036) Cell Division (GO:0051301) DNA Metabolic Process (GO:0006259) GTP Metabolic Process (GO:0046039) Mitotic Cell Cycle (GO:0000278) Mitotic Sister Chromatid Segregation (GO:0000070) Mitotic Spindle Organization (GO:0007052) Positive Regulation Of Protein Binding (GO:0032092) Positive Regulation Of Protein Import Into Nucleus (GO:0042307) Pre-MiRNA Export From Nucleus (GO:0035281) Protein Export From Nucleus (GO:0006611) Protein Import Into Nucleus (GO:0006606) Protein Localization To Nucleolus (GO:1902570) Ribosomal Large Subunit Export From Nucleus (GO:0000055) Ribosomal Small Subunit Export From Nucleus (GO:0000056) Ribosomal Subunit Export From Nucleus (GO:0000054) SnRNA Import Into Nucleus (GO:0061015) Viral Process (GO:0016032) |
| Molecular Function | Cadherin Binding (GO:0045296) Chromatin Binding (GO:0003682) GDP Binding (GO:0019003) GTP Binding (GO:0005525) GTPase Activity (GO:0003924) Magnesium Ion Binding (GO:0000287) Protein Heterodimerization Activity (GO:0046982) RNA Binding (GO:0003723) |
Interactions with Nuclear Envelope proteins (27 interactors) |
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|---|---|---|---|
| Partner (NucEnvDB) | IntAct | Confidence score | |
| O95271 | Poly [ADP-ribose] polymerase tankyrase-1 | EBI-9692184 | 0.40 |
| P41391 | Ran GTPase-activating protein 1 | EBI-1032926 | 0.40 |
| P49792 | E3 SUMO-protein ligase RanBP2 | EBI-3933494 | 0.76 |
| Q86Y07 | Serine/threonine-protein kinase VRK2 | EBI-1795483 | 0.40 |
| Q9ERU9 | E3 SUMO-protein ligase RanBP2 | EBI-2555617 | 0.56 |
| P63279 | SUMO-conjugating enzyme UBC9 | EBI-11105225 | 0.53 |
| Q13625 | Apoptosis-stimulating of p53 protein 2 | EBI-9692277 | 0.64 |
| Q8WUX9 | Charged multivesicular body protein 7 | EBI-25890253 | 0.56 |
| Q14974 | Importin subunit beta-1 | EBI-11115566 | 0.53 |
| P70168 | Importin subunit beta-1 | EBI-15732723 | 0.44 |
| P52297 | Importin subunit beta | EBI-286729 | 0.35 |
| Q9HD47 | Ran guanine nucleotide release factor | EBI-25889861 | 0.56 |
| O14524 | Nuclear envelope integral membrane protein 1 | EBI-21557447 | 0.35 |
| A6NFY4 | Nuclear envelope integral membrane protein 2 | EBI-21557447 | 0.35 |
| P61970 | Nuclear transport factor 2 | EBI-9688194 | 0.81 |
| P57740 | Nuclear pore complex protein Nup107 | EBI-11160436 | 0.35 |
| Q8BH74 | Nuclear pore complex protein Nup107 | EBI-10997196 | 0.35 |
| P49790 | Nuclear pore complex protein Nup153 | EBI-9688194 | 0.64 |
| P49791 | Nuclear pore complex protein Nup153 | EBI-15714795 | 0.67 |
| Q6ZQH8 | Nucleoporin NUP188 | EBI-2563113 | 0.40 |
| P35658 | Nuclear pore complex protein Nup214 | EBI-21557447 | 0.35 |
| Q7Z3B4 | Nucleoporin p54 | EBI-25889945 | 0.56 |
| P37198 | Nuclear pore glycoprotein p62 | EBI-21557447 | 0.35 |
| Q8CEC0 | Nuclear pore complex protein Nup88 | EBI-2562665 | 0.40 |
| Q6PFD9 | Nuclear pore complex protein Nup96 | EBI-10994876 | 0.35 |
| O60356 | Nuclear protein 1 | EBI-15569882 | 0.37 |
| P46060 | Ran GTPase-activating protein 1 | EBI-21557447 | 0.35 | Interactions with other proteins (248 interactors) |
| Partner (UniProt) | IntAct | Confidence score | |
| O42480 | MGC52556 protein (RanBP7) (importin 7 L homeolog) | EBI-286729 | 0.35 |
| Q6GMY9 | Exportin-2 (Exp2) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter) | EBI-286729 | 0.35 |
| P52292 | Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha) | EBI-13942323 | 0.40 |
| Q92973 | Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP) | EBI-1027757 | 0.44 |
| P60709 | Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed] | EBI-353790 | 0.40 |
| P46527 | Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1) | EBI-591758 | 0.40 |
| Q9P2H0 | Centrosomal protein of 126 kDa | EBI-733094 | 0.00 |
| P07196 | Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein) | EBI-737516 | 0.00 |
| P03254 | Early E1A protein (Early E1A 32 kDa protein) | EBI-8626155 | 0.59 |
| P03129 | Protein E7 | EBI-8626194 | 0.44 |
| P43487 | Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1) | EBI-8626224 | 0.61 |
| P03070 | Large T antigen (LT) (LT-AG) (EC 3.6.4.-) | EBI-8626209 | 0.44 |
| P03255 | Early E1A protein (Early E1A 32 kDa protein) | EBI-8544308 | 0.40 |
| Q9H6Z4 | Ran-binding protein 3 (RanBP3) | EBI-992712 | 0.40 |
| P18754 | Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) | EBI-1031180 | 0.88 |
| Q00005 | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PP2A subunit B isoform B55-beta) (PP2A subunit B isoform PR55-beta) (PP2A subunit B isoform R2-beta) (PP2A subunit B isoform beta) | EBI-2211497 | 0.35 |
| Q99986 | Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) | EBI-1795237 | 0.60 |
| Q8IV63 | Inactive serine/threonine-protein kinase VRK3 (Serine/threonine-protein pseudokinase VRK3) (Vaccinia-related kinase 3) | EBI-1795543 | 0.40 |
| O15264 | Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4) | EBI-2255044 | 0.35 |
| Q8IY92 | Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12) | EBI-2371120 | 0.35 |
| Q9BQ83 | Structure-specific endonuclease subunit SLX1 (EC 3.1.-.-) (GIY-YIG domain-containing protein 1) | EBI-2372444 | 0.35 |
| Q9JMK2 | Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1) | EBI-2558429 | 0.40 |
| Q8VD62 | UPF0696 protein C11orf68 homolog (Basophilic leukemia-expressed protein Bles03) (Protein WF-3) | EBI-2562857 | 0.40 |
| Q60610 | Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1) | EBI-7567120 | 0.44 |
| Q6ZPF3 | Rho guanine nucleotide exchange factor TIAM2 (SIF and TIAM1-like exchange factor) (T-lymphoma invasion and metastasis-inducing protein 2) (TIAM-2) | EBI-7567337 | 0.44 |
| P43354 | Nuclear receptor subfamily 4 group A member 2 (Immediate-early response protein NOT) (Orphan nuclear receptor NURR1) (Transcriptionally-inducible nuclear receptor) | EBI-2681788 | 0.00 |
| Q15796 | Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2) | EBI-2684985 | 0.00 |
| O76187 | Darlin (Armadillo-like protein A) | EBI-2905901 | 0.40 |
| P18124 | 60S ribosomal protein L7 (Large ribosomal subunit protein uL30) | EBI-8297497 | 0.40 |
| Q9HAV4 | Exportin-5 (Exp5) (Ran-binding protein 21) | EBI-2938145 | 0.40 |
| O94829 | Importin-13 (Imp13) (Karyopherin-13) (Kap13) (Ran-binding protein 13) (RanBP13) | EBI-8534600 | 0.73 |
| Q99666 | RANBP2-like and GRIP domain-containing protein 5/6 (Ran-binding protein 2-like 1/2) (RanBP2-like 1/2) (RanBP2L1) (RanBP2L2) (Sperm membrane protein BS-63) | EBI-3940764 | 0.55 |
| Q5TAQ9 | DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A) | EBI-7817945 | 0.27 |
| O95758 | Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1) | EBI-7850130 | 0.35 |
| P19320 | Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) | EBI-6189915 | 0.35 |
| P10209 | Capsid vertex component 2 | EBI-6509326 | 0.37 |
| P47813 | Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C) | EBI-9207355 | 0.59 |
| O15392 | Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin) | EBI-9548404 | 0.63 |
| P42771 | Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A) | EBI-9691810 | 0.46 |
| Q8WUF5 | RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein) | EBI-9692274 | 0.65 |
| Q8WVL7 | Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) | EBI-9691643 | 0.40 |
| Q91974 | NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (REL-associated protein pp40) | EBI-9691221 | 0.40 |
| O14974 | Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit) | EBI-9692208 | 0.40 |
| Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 (TrpV4) (Osm-9-like TRP channel 4) (OTRPC4) (Transient receptor potential protein 12) (TRP12) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) | EBI-9692161 | 0.40 |
| Q06547 | GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2) (Nuclear respiratory factor 2) (Transcription factor E4TF1-47) (Transcription factor E4TF1-53) | EBI-25889543 | 0.56 |
| Q96KQ4 | Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B) | EBI-9692121 | 0.40 |
| P25963 | NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3) | EBI-9692133 | 0.40 |
| O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1) | EBI-10103342 | 0.35 |
| Q13418 | Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK) | EBI-10103376 | 0.35 |
| P29597 | Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2) | EBI-10104620 | 0.35 |
| Q96FW1 | Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1) | EBI-10770198 | 0.35 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] | EBI-11322719 | 0.35 |
| P05412 | Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39) | EBI-11323169 | 0.35 |
| Q96L14 | Cep170-like protein (CEP170 pseudogene 1) | EBI-11022408 | 0.35 |
| Q8VE37 | Regulator of chromosome condensation (Chromosome condensation protein 1) | EBI-11043815 | 0.35 |
| P63280 | SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (mUBC9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) | EBI-11044140 | 0.35 |
| P34022 | Ran-specific GTPase-activating protein (HpaII tiny fragments locus 9a protein) (Ran-binding protein 1) (RANBP1) | EBI-11080066 | 0.35 |
| Q8CAQ8 | MICOS complex subunit Mic60 (Mitochondrial inner membrane protein) (Mitofilin) | EBI-11096643 | 0.35 |
| Q9Y496 | Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A) | EBI-11097996 | 0.35 |
| P26367 | Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin) | EBI-11107399 | 0.35 |
| O43896 | Kinesin-like protein KIF1C | EBI-11140183 | 0.35 |
| Q3V6T2 | Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1) | EBI-11141559 | 0.35 |
| Q9UBX2 | Double homeobox protein 4 (Double homeobox protein 10) | EBI-11614356 | 0.35 |
| O43592 | Exportin-T (Exportin(tRNA)) (tRNA exportin) | EBI-24355918 | 0.56 |
| O14787 | Transportin-2 (Karyopherin beta-2b) | EBI-24386976 | 0.56 |
| Q9UIA9 | Exportin-7 (Exp7) (Ran-binding protein 16) | EBI-24411618 | 0.56 |
| Q9H9L7 | Akirin-1 | EBI-21557447 | 0.35 |
| Q96P70 | Importin-9 (Imp9) (Ran-binding protein 9) (RanBP9) | EBI-21557447 | 0.35 |
| Q70UQ0 | Inhibitor of nuclear factor kappa-B kinase-interacting protein (I kappa-B kinase-interacting protein) (IKBKB-interacting protein) (IKK-interacting protein) | EBI-21557447 | 0.35 |
| Q69YH5 | Cell division cycle-associated protein 2 (Recruits PP1 onto mitotic chromatin at anaphase protein) (Repo-Man) | EBI-21557447 | 0.35 |
| P0DJD1 | RANBP2-like and GRIP domain-containing protein 2 (Ran-binding protein 2-like 2) (RanBP2-like 2) (RanBP2L2) | EBI-21557447 | 0.35 |
| Q15398 | Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein) (HURP) | EBI-21557447 | 0.35 |
| O14715 | RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) | EBI-21557447 | 0.35 |
| O00629 | Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4) | EBI-21557447 | 0.35 |
| Q53H80 | Akirin-2 | EBI-21567350 | 0.35 |
| P54645 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26) | EBI-16361875 | 0.35 |
| P80386 | 5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb) (5'-AMP-activated protein kinase 40 kDa subunit) | EBI-16362252 | 0.35 |
| P61925 | cAMP-dependent protein kinase inhibitor alpha (PKI-alpha) (cAMP-dependent protein kinase inhibitor, muscle/brain isoform) | EBI-15886863 | 0.52 |
| Q6P5F9 | Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) | EBI-15887025 | 0.68 |
| O95149 | Snurportin-1 (RNA U transporter 1) | EBI-16064299 | 0.40 |
| Q01968 | Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Lowe oculocerebrorenal syndrome protein) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86) | EBI-16412116 | 0.35 |
| Q9EPK7 | Exportin-7 (Exp7) (Ran-binding protein 16) | EBI-17168930 | 0.35 |
| Q07960 | Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP) | EBI-17172410 | 0.40 |
| Q9D3W4 | GPN-loop GTPase 3 (ATP-binding domain 1 family member C) | EBI-17172527 | 0.40 |
| Q9CWR2 | Histone-lysine N-methyltransferase SMYD3 (EC 2.1.1.354) (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1) | EBI-17172552 | 0.40 |
| O35381 | Acidic leucine-rich nuclear phosphoprotein 32 family member A (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (LANP) (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) | EBI-17172576 | 0.40 |
| Q61074 | Protein phosphatase 1G (EC 3.1.3.16) (Fibroblast growth factor-inducible protein 13) (FIN13) (Protein phosphatase 1C) (Protein phosphatase 2C isoform gamma) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) | EBI-17172591 | 0.40 |
| Q9EQU5 | Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I) | EBI-17172606 | 0.40 |
| O09012 | Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (PXR1P) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1) | EBI-17172621 | 0.40 |
| Q8VE09 | Tetratricopeptide repeat protein 39C (TPR repeat protein 39C) | EBI-17172636 | 0.40 |
| Q8VCE2 | GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (XPA-binding protein 1) | EBI-17172666 | 0.40 |
| Q9Z0P7 | Suppressor of fused homolog | EBI-17172681 | 0.40 |
| P97822 | Acidic leucine-rich nuclear phosphoprotein 32 family member E (Cerebellar postnatal development protein 1) (LANP-like protein) (LANP-L) | EBI-17172705 | 0.40 |
| Q9Z1K5 | E3 ubiquitin-protein ligase ARIH1 (EC 2.3.2.31) (Protein ariadne-1 homolog) (ARI-1) (RING-type E3 ubiquitin transferase ARIH1) (UbcH7-binding protein) (UbcM4-interacting protein 77) (Ubiquitin-conjugating enzyme E2-binding protein 1) | EBI-17172733 | 0.40 |
| P58043 | Sestrin-2 (EC 1.11.1.-) | EBI-17172748 | 0.40 |
| Q8BP48 | Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1) | EBI-17172763 | 0.40 |
| Q60737 | Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1) | EBI-17172823 | 0.40 |
| P15659 | Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2) | EBI-25769098 | 0.37 |
| P03430 | RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) (RNA-directed RNA polymerase subunit P1) | EBI-25769362 | 0.37 |
| P03427 | Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3) | EBI-25769803 | 0.37 |
| Q92731 | Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2) | EBI-20764883 | 0.35 |
| O75391 | Sperm-associated antigen 7 | EBI-20907624 | 0.40 |
| Q93073 | Selenocysteine insertion sequence-binding protein 2-like (SECIS-binding protein 2-like) | EBI-20910936 | 0.40 |
| O75054 | Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3) | EBI-20912478 | 0.40 |
| Q9NRL2 | Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1) | EBI-20921060 | 0.40 |
| P16401 | Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3) | EBI-20928448 | 0.40 |
| Q93079 | Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j) | EBI-20929824 | 0.40 |
| Q16695 | Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4) | EBI-20929816 | 0.40 |
| Q9HAP2 | MLX-interacting protein (Class E basic helix-loop-helix protein 36) (bHLHe36) (Transcriptional activator MondoA) | EBI-20933308 | 0.40 |
| P62805 | Histone H4 | EBI-20933064 | 0.40 |
| Q9BXS9 | Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1) | EBI-20936124 | 0.40 |
| A2A935 | Histone-lysine N-methyltransferase PRDM16 (EC 2.1.1.367) (PR domain zinc finger protein 16) (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1) | EBI-21022882 | 0.35 |
| P14404 | Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein homolog) | EBI-21026252 | 0.35 |
| Q5T7N2 | LINE-1 type transposase domain-containing protein 1 (ES cell-associated protein 11) | EBI-20993270 | 0.35 |
| P13569 | Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel) | EBI-25416349 | 0.53 |
| Q9UQC2 | GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100) | EBI-25384304 | 0.35 |
| P63000 | Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1) | EBI-25387902 | 0.35 |
| P06239 | Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK) | EBI-25394571 | 0.35 |
| P0DOF2 | Matrix protein (Phosphoprotein M2) | EBI-25603126 | 0.35 |
| P69479 | Phosphoprotein (Protein P) (Protein M1) | EBI-25568051 | 0.35 |
| Q5EP34 | Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2) | EBI-25772822 | 0.35 |
| Q92797 | Symplekin | EBI-25889687 | 0.56 |
| O43829 | Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5) | EBI-25889679 | 0.56 |
| P49459 | Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A) | EBI-25889671 | 0.56 |
| Q12888 | TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1) | EBI-25889663 | 0.56 |
| P54274 | Telomeric repeat-binding factor 1 (NIMA-interacting protein 2) (TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1) | EBI-25889655 | 0.56 |
| O60927 | E3 ubiquitin-protein ligase PPP1R11 (EC 2.3.2.27) (Hemochromatosis candidate gene V protein) (HCG V) (Protein phosphatase 1 regulatory subunit 11) (Protein phosphatase inhibitor 3) | EBI-25889647 | 0.56 |
| P22307 | Sterol carrier protein 2 (SCP-2) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Non-specific lipid-transfer protein) (NSL-TP) (Propanoyl-CoA C-acyltransferase) (EC 2.3.1.176) (SCP-2/3-oxoacyl-CoA thiolase) (SCP-2/thiolase) (EC 2.3.1.16) (SCP-chi) (SCPX) (Sterol carrier protein X) (SCP-X) | EBI-25889639 | 0.56 |
| P62701 | 40S ribosomal protein S4, X isoform (SCR10) (Single copy abundant mRNA protein) (Small ribosomal subunit protein eS4) | EBI-25889631 | 0.56 |
| Q15382 | GTP-binding protein Rheb (Ras homolog enriched in brain) | EBI-25889623 | 0.56 |
| P47804 | RPE-retinal G protein-coupled receptor | EBI-25889615 | 0.56 |
| Q04206 | Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3) | EBI-25889607 | 0.56 |
| Q09028 | Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) | EBI-25889599 | 0.56 |
| Q07869 | Peroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1) | EBI-25889591 | 0.56 |
| P36954 | DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5) | EBI-25889583 | 0.56 |
| O15534 | Period circadian protein homolog 1 (hPER1) (Circadian clock protein PERIOD 1) (Circadian pacemaker protein Rigui) | EBI-25889575 | 0.56 |
| P36639 | Oxidized purine nucleoside triphosphate hydrolase (EC 3.6.1.56) (2-hydroxy-dATP diphosphatase) (7,8-dihydro-8-oxoguanine triphosphatase) (8-oxo-dGTPase) (Methylated purine nucleoside triphosphate hydrolase) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 1) (Nudix motif 1) | EBI-25889567 | 0.56 |
| P27338 | Amine oxidase [flavin-containing] B (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B) | EBI-25889559 | 0.56 |
| Q9NRZ9 | Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6) | EBI-25889551 | 0.56 |
| P06241 | Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn) | EBI-25889535 | 0.56 |
| P35222 | Catenin beta-1 (Beta-catenin) | EBI-25889527 | 0.56 |
| Q86WV5 | CST complex subunit TEN1 (Protein telomeric pathways with STN1 homolog) (Telomere length regulation protein TEN1 homolog) | EBI-25889519 | 0.56 |
| P20807 | Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1) | EBI-25889511 | 0.56 |
| P17655 | Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain) | EBI-25889503 | 0.56 |
| A0A384MDV8 | Epididymis secretory sperm binding protein | EBI-25889495 | 0.56 |
| P06276 | Cholinesterase (EC 3.1.1.8) (Acylcholine acylhydrolase) (Butyrylcholine esterase) (Choline esterase II) (Pseudocholinesterase) | EBI-25889487 | 0.56 |
| Q14032 | Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Bile acid-CoA thioesterase) (Choloyl-CoA hydrolase) (EC 3.1.2.27) (Glycine N-choloyltransferase) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2) | EBI-25889479 | 0.56 |
| P36406 | E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23) | EBI-25889471 | 0.56 |
| P09525 | Annexin A4 (35-beta calcimedin) (Annexin IV) (Annexin-4) (Carbohydrate-binding protein p33/p41) (Chromobindin-4) (Endonexin I) (Lipocortin IV) (P32.5) (PP4-X) (Placental anticoagulant protein II) (PAP-II) (Protein II) | EBI-25889463 | 0.56 |
| Q9Y3D0 | Cytosolic iron-sulfur assembly component 2B (MSS19-interacting protein of 18 kDa) (Mitotic spindle-associated MMXD complex subunit MIP18) (Protein FAM96B) | EBI-25889937 | 0.56 |
| Q66PJ3 | ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL-6-interacting protein 4) (Aip-4) (HSP-975) (HSVI-binding protein) (SR-15) (SRp25) (SR-25) (Splicing factor SRrp37) | EBI-25889919 | 0.56 |
| Q96IZ7 | Serine/Arginine-related protein 53 (SRrp53) (Arginine/serine-rich coiled-coil protein 1) | EBI-25889911 | 0.56 |
| Q9UK76 | Jupiter microtubule associated homolog 1 (Androgen-regulated protein 2) (Hematological and neurological expressed 1 protein) [Cleaved into: Jupiter microtubule associated homolog 1, N-terminally processed] | EBI-25889903 | 0.56 |
| P0DPB6 | DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19) | EBI-25889895 | 0.56 |
| Q49AJ0 | Protein FAM135B | EBI-25889885 | 0.56 |
| Q9Y303 | N-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase) (EC 3.5.1.25) (Amidohydrolase domain-containing protein 2) | EBI-25889877 | 0.56 |
| Q9NNX6 | CD209 antigen (C-type lectin domain family 4 member L) (Dendritic cell-specific ICAM-3-grabbing non-integrin 1) (DC-SIGN) (DC-SIGN1) (CD antigen CD209) | EBI-25889869 | 0.56 |
| Q9H0W9 | Ester hydrolase C11orf54 (EC 3.1.-.-) | EBI-25889853 | 0.56 |
| Q9UIK5 | Tomoregulin-2 (TR-2) (Hyperplastic polyposis protein 1) (Transmembrane protein with EGF-like and two follistatin-like domains) | EBI-25889845 | 0.56 |
| Q14181 | DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit) | EBI-25889837 | 0.56 |
| Q86US8 | Telomerase-binding protein EST1A (EC 3.1.-.-) (Ever shorter telomeres 1A) (hEST1A) (Nonsense mediated mRNA decay factor SMG6) (Smg-6 homolog) (hSmg5/7a) | EBI-25889829 | 0.56 |
| Q13573 | SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein) | EBI-25889821 | 0.56 |
| O00472 | RNA polymerase II elongation factor ELL2 | EBI-25889813 | 0.56 |
| Q96H20 | Vacuolar-sorting protein SNF8 (ELL-associated protein of 30 kDa) (ESCRT-II complex subunit VPS22) (hVps22) | EBI-25889805 | 0.56 |
| O95070 | Protein YIF1A (54TMp) (YIP1-interacting factor homolog A) | EBI-25889797 | 0.56 |
| Q9Y614 | Actin-like protein 7B (Actin-like-7-beta) | EBI-25889789 | 0.56 |
| O60506 | Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) | EBI-25889781 | 0.56 |
| Q13901 | Nuclear nucleic acid-binding protein C1D (hC1D) | EBI-25889773 | 0.56 |
| Q8N5U6 | RING finger protein 10 | EBI-25889765 | 0.56 |
| Q96EY1 | DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog) | EBI-25889755 | 0.56 |
| Q86V28 | AP-1 complex subunit gamma | EBI-25889739 | 0.56 |
| O95674 | Phosphatidate cytidylyltransferase 2 (EC 2.7.7.41) (CDP-DAG synthase 2) (CDP-DG synthase 2) (CDP-diacylglycerol synthase 2) (CDS 2) (CDP-diglyceride pyrophosphorylase 2) (CDP-diglyceride synthase 2) (CTP:phosphatidate cytidylyltransferase 2) | EBI-25889731 | 0.56 |
| P0C870 | Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (EC 1.14.11.63) (EC 3.4.-.-) (JmjC domain-containing protein 7) (Jumonji domain-containing protein 7) (L-lysine (3S)-hydroxylase JMJD7) | EBI-25889723 | 0.56 |
| O15273 | Telethonin (Titin cap protein) | EBI-25889715 | 0.56 |
| O00257 | E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2) | EBI-25889707 | 0.56 |
| Q92782 | Zinc finger protein neuro-d4 (BRG1-associated factor 45B) (BAF45B) (D4, zinc and double PHD fingers family 1) | EBI-25889697 | 0.56 |
| Q9NTN9 | Semaphorin-4G | EBI-25890047 | 0.56 |
| Q5W111 | SPRY domain-containing protein 7 (Chronic lymphocytic leukemia deletion region gene 6 protein) (CLL deletion region gene 6 protein) | EBI-25890039 | 0.56 |
| Q05CR2 | ZNF248 protein | EBI-25890031 | 0.56 |
| Q6GQQ9 | OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne) | EBI-25890021 | 0.56 |
| Q9BPU6 | Dihydropyrimidinase-related protein 5 (DRP-5) (CRMP3-associated molecule) (CRAM) (Collapsin response mediator protein 5) (CRMP-5) (UNC33-like phosphoprotein 6) (ULIP-6) | EBI-25890013 | 0.56 |
| Q8IYM2 | Ribonuclease SLFN12 (EC 3.1.-.-) (Schlafen family member 12) | EBI-25890005 | 0.56 |
| Q9NX94 | WW domain binding protein 1-like (Outcome predictor in acute leukemia 1) | EBI-25889997 | 0.56 |
| Q8TBB5 | Kelch domain-containing protein 4 | EBI-25889989 | 0.56 |
| Q9UKG9 | Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137) | EBI-25889981 | 0.56 |
| Q9UGL9 | Cysteine-rich C-terminal protein 1 (Protein NICE-1) | EBI-25889973 | 0.56 |
| Q6UY14 | ADAMTS-like protein 4 (ADAMTSL-4) (Thrombospondin repeat-containing protein 1) | EBI-25889963 | 0.56 |
| Q9NSI6 | Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9) | EBI-25889955 | 0.56 |
| Q9P1Q0 | Vacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p) | EBI-25889929 | 0.56 |
| Q53FD0 | Zinc finger C2HC domain-containing protein 1C | EBI-25890107 | 0.56 |
| Q6N063 | 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-) | EBI-25890097 | 0.56 |
| Q9BUL5 | PHD finger protein 23 (PDH-containing protein JUNE-1) | EBI-25890089 | 0.56 |
| Q9H2C1 | LIM/homeobox protein Lhx5 (LIM homeobox protein 5) | EBI-25890057 | 0.56 |
| Q96BR5 | Cytochrome c oxidase assembly factor 7 (Beta-lactamase hcp-like protein) (Respiratory chain assembly factor 1) (Sel1 repeat-containing protein 1) | EBI-25890073 | 0.56 |
| A0A0A0MR05 | G protein beta subunit-like | EBI-25890065 | 0.56 |
| Q9BQA1 | Methylosome protein 50 (MEP-50) (Androgen receptor cofactor p44) (WD repeat-containing protein 77) (p44/Mep50) | EBI-25890081 | 0.56 |
| Q9H0Y0 | Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like) | EBI-25890197 | 0.56 |
| Q9C004 | Protein sprouty homolog 4 (Spry-4) | EBI-25890181 | 0.56 |
| Q8N5Z5 | BTB/POZ domain-containing protein KCTD17 | EBI-25890115 | 0.56 |
| Q96BD6 | SPRY domain-containing SOCS box protein 1 (SSB-1) | EBI-25890157 | 0.56 |
| Q3SXR2 | Uncharacterized protein C3orf36 | EBI-25890149 | 0.56 |
| Q9H8K7 | ATPase PAAT (EC 3.6.1.-) (Protein associated with ABC transporters) (PAAT) | EBI-25890141 | 0.56 |
| B7Z3E8 | cDNA FLJ51208 | EBI-25890133 | 0.56 |
| Q6IN84 | rRNA methyltransferase 1, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1145)-2'-O)-methyltransferase) (16S rRNA [Gm1145] 2'-O-methyltransferase) | EBI-25890125 | 0.56 |
| Q16609 | Putative apolipoprotein(a)-like protein 2 (Apo(a)-like protein 2) (Lp(a)-liker protein 2) (Apolipoprotein a-related gene C protein) (Apo(a)rg-C) | EBI-25890165 | 0.56 |
| Q494V2 | Cilia- and flagella-associated protein 100 (Coiled-coil domain-containing protein 37) | EBI-25890475 | 0.56 |
| Q8IWT0 | Protein archease (Protein ZBTB8OS) (Zinc finger and BTB domain-containing opposite strand protein 8) | EBI-25890451 | 0.56 |
| Q66K80 | Putative uncharacterized protein RUSC1-AS1 (RUSC1 antisense RNA 1) (RUSC1 antisense gene protein 1) | EBI-25890443 | 0.56 |
| Q3SX64 | Outer dense fiber protein 3-like protein 2 | EBI-25890435 | 0.56 |
| Q8N0U6 | Putative uncharacterized protein encoded by LINC00518 | EBI-25890427 | 0.56 |
| Q496A3 | Spermatogenesis-associated serine-rich protein 1 | EBI-25890419 | 0.56 |
| Q96Q83 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (EC 1.14.11.33) (EC 1.14.11.54) (Alkylated DNA repair protein alkB homolog 3) (hABH3) (DEPC-1) (Prostate cancer antigen 1) | EBI-25890411 | 0.56 |
| Q658K8 | Putative elongation factor 1-delta-like protein (Putative EF-1-delta-like pseudogene 3 protein) | EBI-25890403 | 0.56 |
| A6NJ78 | 12S rRNA N4-methylcytidine (m4C) methyltransferase (12S rRNA m4C methyltransferase) (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1) (Methyltransferase-like protein 15) | EBI-25890393 | 0.56 |
| Q8IZU1 | Protein FAM9A | EBI-25890385 | 0.56 |
| Q9H2U1 | ATP-dependent DNA/RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAD/H box polypeptide 36) (DEAH-box protein 36) (G4-resolvase-1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element protein) | EBI-25890377 | 0.56 |
| Q6PJW8 | Consortin | EBI-25890369 | 0.56 |
| Q6DHV7 | Adenosine deaminase-like protein (EC 3.5.4.-) (Adenosine deaminase-like protein isoform 1) (N6-mAMP deaminase) (HsMAPDA) (N6-methyl-AMP aminohydrolase) | EBI-25890361 | 0.56 |
| Q96MA6 | Adenylate kinase 8 (AK 8) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 8) | EBI-25890353 | 0.56 |
| Q6ZNL6 | FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23) | EBI-25890343 | 0.56 |
| Q96LX8 | Zinc finger protein 597 | EBI-25890335 | 0.56 |
| Q86WT6 | E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27) (RFP-like domain-containing protein trimless) (RING finger protein 36) (RING-type E3 ubiquitin transferase TRIM69) (Tripartite motif-containing protein 69) | EBI-25890327 | 0.56 |
| Q6ZMI0 | Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (KLRAQ motif-containing protein 1) | EBI-25890319 | 0.56 |
| Q8N1A0 | Keratin-like protein KRT222 (Keratin-222) (Keratin-222 pseudogene) | EBI-25890311 | 0.56 |
| Q6XD76 | Achaete-scute homolog 4 (ASH-4) (hASH4) (Achaete-scute-like protein 4) (Class A basic helix-loop-helix protein 44) (bHLHa44) | EBI-25890303 | 0.56 |
| Q96A09 | Terminal nucleotidyltransferase 5B (EC 2.7.7.19) (Non-canonical poly(A) polymerase FAM46B) | EBI-25890295 | 0.56 |
| Q8IYG6 | Leucine-rich repeat-containing protein 56 | EBI-25890285 | 0.56 |
| Q96Q07 | BTB/POZ domain-containing protein 9 | EBI-25890277 | 0.56 |
| Q53NU3 | Uncharacterized protein tmp_locus_54 (cDNA, FLJ92284) | EBI-25890269 | 0.56 |
| Q9BT25 | HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48) | EBI-25890261 | 0.56 |
| Q8WUD1 | Ras-related protein Rab-2B (EC 3.6.5.2) | EBI-25890237 | 0.56 |
| Q49A26 | Cytokine-like nuclear factor N-PAC (NPAC) (3-hydroxyisobutyrate dehydrogenase-like protein) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60) (Nuclear protein of 60 kDa) (Nucleosome-destabilizing factor) (hNDF) (Putative oxidoreductase GLYR1) | EBI-25890229 | 0.56 |
| Q6NXT2 | Histone H3.3C (Histone H3.5) | EBI-25890517 | 0.56 |
| Q8WW27 | Putative C->U-editing enzyme APOBEC-4 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4) | EBI-25890509 | 0.56 |
| Q3KNS6 | Zinc finger protein 829 | EBI-25890483 | 0.56 |
| A2RUH7 | Myosin-binding protein H-like | EBI-25890459 | 0.56 |
| Q5JTY5 | Zinc-regulated GTPase metalloprotein activator 1C (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 3) (COBW domain-containing protein 3) | EBI-25890525 | 0.56 |
| P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1) | EBI-25894615 | 0.56 |
| Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 (Spred-1) (hSpred1) | EBI-25930873 | 0.56 |
| P42858 | Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment] | EBI-25952651 | 0.56 |
| P37840 | Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP) | EBI-25983264 | 0.56 |
| Q09161 | Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) | EBI-26398700 | 0.35 |
| P10636 | Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau) | EBI-26374389 | 0.27 |
| Q99608 | Necdin | EBI-26955247 | 0.27 |
| P06401 | Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3) | EBI-26871590 | 0.35 |
| F1PAA9 | Cadherin-1 (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3] | EBI-27079701 | 0.27 |
| P35226 | Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51) | EBI-27109494 | 0.35 |
| Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1) | EBI-28952196 | 0.27 |
Database | Links |
| UNIPROT | P62826 A8K3Z8 P17080 P28746 P28747 Q6IPB2 Q86V08 Q8NI90 Q9CSP3 Q9CWI7 Q9CZA2 Q9UDJ5 Q9UEU9 |
| PDB | 1I2M 1IBR 1K5D 1K5G 1QBK 1RRP 2MMC 2MMG 2N1B 3CH5 3EA5 3GJ0 3GJ3 3GJ4 3GJ5 3GJ6 3GJ7 3GJ8 3GJX 3NBY 3NBZ 3NC0 3NC1 3ZJY 4C0Q 4GMX 4GPT 4HAT 4HAU 4HAV 4HAW 4HAX 4HAY 4HAZ 4HB0 4HB2 4HB3 4HB4 4OL0 4WVF 5CIQ 5CIT 5CIW 5CJ2 5CLL 5CLQ 5DH9 5DHA 5DHF 5DI9 5DIF 5DIS 5DLQ 5FYQ 5JLJ 5UWH 5UWI 5UWJ 5UWO 5UWP 5UWQ 5UWR 5UWS 5UWT 5UWU 5UWW 5YRO 5YST 5YSU 5YTB 5ZPU 6A38 6A3A 6A3B 6A3C 6A3E 6CIT 6KFT 6LQ9 6M60 6M6X 6Q82 6Q84 6TVO 6X2M 6X2O 6X2P 6X2R 6X2S 6X2U 6X2V 6X2W 6X2X 6X2Y 6XJP 6XJR 6XJS 6XJT 6XJU 7B51 7CND 7DBG 7L5E |
| Pfam | PF00071 |
| PROSITE | PS51418 |
| OMIM | 601179 |
| DisGeNET | 5901 |
National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory