Interactions with Nuclear Envelope proteins (22 interactors)
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Partner (NucEnvDB) IntAct Confidence score
P63279 SUMO-conjugating enzyme UBC9 EBI-11105225 0.75
Q9ERU9 E3 SUMO-protein ligase RanBP2 EBI-2555617 0.40
P49792 Self EBI-3450084 0.00
Q96EE3 Nucleoporin SEH1 EBI-11086798 0.35
P63165 Small ubiquitin-related modifier 1 EBI-30826718 0.44
Q8TD16 Protein bicaudal D homolog 2 EBI-15847951 0.40
Q921C5 Protein bicaudal D homolog 2 EBI-15847872 0.63
Q8WYP5 Protein ELYS EBI-9050350 0.40
P04626 Receptor tyrosine-protein kinase erbB-2 EBI-4373195 0.46
Q14974 Importin subunit beta-1 EBI-11115566 0.35
P70168 Importin subunit beta-1 EBI-15732742 0.36
O14524 Nuclear envelope integral membrane protein 1 EBI-21695903 0.35
P57740 Nuclear pore complex protein Nup107 EBI-11160436 0.35
Q8BH74 Nuclear pore complex protein Nup107 EBI-10997196 0.35
P49790 Nuclear pore complex protein Nup153 EBI-11076796 0.35
Q99P88 Nuclear pore complex protein Nup155 EBI-10997466 0.35
Q80U93 Nuclear pore complex protein Nup214 EBI-11014856 0.35
Q9BVL2 Nucleoporin p58/p45 EBI-11077390 0.35
Q6PFD9 Nuclear pore complex protein Nup96 EBI-10994876 0.35
Q9UBU9 Nuclear RNA export factor 1 EBI-6262548 0.53
P46060 Ran GTPase-activating protein 1 EBI-21928721 0.62
P62826 GTP-binding nuclear protein Ran EBI-3933494 0.76
Interactions with other proteins (81 interactors)
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Partner (UniProt) IntAct Confidence score
O60260 E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2) EBI-973169 0.64
P02768 Albumin EBI-1224020 0.35
P01106 Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64) EBI-1237540 0.35
P11388 DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme) EBI-1773456 0.40
Q01320 DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme) EBI-1775292 0.40
P03116 Replication protein E1 (EC 3.6.4.12) (ATP-dependent helicase E1) EBI-7414341 0.40
P33176 Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC) EBI-8602425 0.40
Q9Z0E3 Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog) EBI-2549710 0.35
Q9QWT9 Kinesin-like protein KIFC1 EBI-2558911 0.40
Q07832 Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) EBI-2560950 0.40
Q5NET2 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) EBI-2801802 0.00
Q81LI7 Aspartate--tRNA(Asp/Asn) ligase (EC 6.1.1.23) (Aspartyl-tRNA synthetase) (AspRS) (Non-discriminating aspartyl-tRNA synthetase) (ND-AspRS) EBI-2823809 0.00
A0A380PEL1 Putative HlyD family secretion protein EBI-2841285 0.00
Q0WCK7 Outer membrane protein assembly factor BamC EBI-2842408 0.00
A0A380PDY1 Oligogalacturonate lyase (EC 4.2.2.6) EBI-2856426 0.00
Q13573 SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein) EBI-7950968 0.35
Q99459 Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein) EBI-7954144 0.35
Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta) EBI-3045543 0.35
P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein) EBI-3046676 0.35
P25054 Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5) EBI-3437454 0.00
Q12802 A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47) EBI-3449822 0.00
Q4LE39 AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Breast cancer-associated antigen BRCAA1) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1) EBI-3449836 0.00
Q9Y613 FH1/FH2 domain-containing protein 1 (Formin homolog overexpressed in spleen 1) (FHOS) (Formin homology 2 domain-containing protein 1) EBI-3449871 0.00
P30533 Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) EBI-3449926 0.00
P21675 Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) EBI-3450016 0.00
Q96RY7 Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2) EBI-3450063 0.00
P52292 Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha) EBI-3931429 0.37
Q13616 Cullin-1 (CUL-1) EBI-3933504 0.37
Q14324 Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform) EBI-5661299 0.00
Q53GG5 PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha-actinin-2-associated LIM protein) EBI-5662564 0.00
O15169 Axin-1 (Axis inhibition protein 1) (hAxin) EBI-6169699 0.35
P05919 Protein Vpu (U ORF protein) (Viral protein U) EBI-6176256 0.35
Q9UBE8 Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1) EBI-6381385 0.35
Q13617 Cullin-2 (CUL-2) EBI-21327106 0.35
Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin) EBI-6515052 0.53
Q13043 Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)] EBI-10049645 0.35
Q72497 Gag polyprotein [Cleaved into: Matrix protein p17 (MA)] EBI-9943756 0.44
Q99853 Forkhead box protein B1 (Transcription factor FKH-5) EBI-11317404 0.35
Q12952 Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7) EBI-11318689 0.35
Q9C009 Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1) EBI-11319301 0.35
P05412 Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39) EBI-11323169 0.35
P03220 Protein BGLF3 EBI-11722152 0.35
Q2MG95 BVLF1 EBI-11733653 0.35
Q9Z1B5 Mitotic spindle assembly checkpoint protein MAD2A (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1) EBI-10996176 0.35
E9PUA5 Kinesin-like protein EBI-10999661 0.35
Q8VE37 Regulator of chromosome condensation (Chromosome condensation protein 1) EBI-11043815 0.35
P63280 SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (mUBC9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) EBI-11044140 0.35
E9Q3P4 Centromere protein F EBI-11086604 0.35
Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB (DnaJ homolog subfamily C member 20) [Cleaved into: Iron-sulfur cluster co-chaperone protein HscB, cytoplasmic (C-HSC20); Iron-sulfur cluster co-chaperone protein HscB, mitochondrial] EBI-13943458 0.35
P18754 Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) EBI-21567271 0.35
P61769 Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3] EBI-21675069 0.35
Q9BXS6 Nucleolar and spindle-associated protein 1 (NuSAP) EBI-21691494 0.35
Q9Y228 TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3) EBI-21696444 0.35
Q8IYT4 Katanin p60 ATPase-containing subunit A-like 2 (Katanin p60 subunit A-like 2) (EC 5.6.1.1) (p60 katanin-like 2) EBI-16421609 0.35
Q6ZNJ1 Neurobeachin-like protein 2 EBI-16749633 0.35
Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain) EBI-20737473 0.35
P10809 60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) EBI-20901016 0.40
Q8N9W5 Dynein axonemal assembly factor 3 EBI-20913366 0.40
Q92878 DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-) EBI-20918244 0.40
Q6P4A8 Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C] EBI-20931312 0.40
A2A935 Histone-lysine N-methyltransferase PRDM16 (EC 2.1.1.367) (PR domain zinc finger protein 16) (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1) EBI-21022882 0.35
P14404 Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein homolog) EBI-21026252 0.35
Q9Y275 Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form] EBI-21266480 0.35
O00213 Amyloid beta precursor protein binding family B member 1 (Amyloid-beta A4 precursor protein-binding family B member 1) (Protein Fe65) EBI-21017901 0.35
P03372 Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1) EBI-21301141 0.35
O00499 Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1) EBI-21385533 0.00
Q5NHH2 Hypothetical lipoprotein EBI-22299104 0.37
P11234 Ras-related protein Ral-B (EC 3.6.5.2) EBI-25376255 0.35
P83105 Serine protease HTRA4 (EC 3.4.21.-) (High-temperature requirement factor A4) EBI-25745135 0.35
Q9C0B5 Palmitoyltransferase ZDHHC5 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375) EBI-25636144 0.35
Q9Y5P2 Chondrosarcoma-associated gene 2/3 protein (Cancer/testis antigen 24.2) (CT24.2) (Taxol-resistant-associated gene 3 protein) (TRAG-3) EBI-26354638 0.35
P42685 Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5) EBI-28935169 0.35
P53350 Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) EBI-28938281 0.35
Q86UX6 Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase 3) EBI-28942129 0.35
Q96GD4 Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B) EBI-28944360 0.35
Q9Y6S9 Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1) EBI-28948011 0.35
Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1) EBI-28952196 0.27
Q05D32 CTD small phosphatase-like protein 2 (CTDSP-like 2) (EC 3.1.3.-) EBI-27113232 0.35
O15297 Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1) EBI-27113880 0.35
Q13283 Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1) EBI-28955349 0.35
Q07866 Kinesin light chain 1 (KLC 1) EBI-30822114 0.44
National and Kapodistrian University of Athens
Department of Biology
Biophysics & Bioinformatics Laboratory