Vesicle-associated membrane protein-associated protein A - Homo sapiens

Vesicle-associated membrane protein-associated protein A (Homo sapiens)

FASTA TEXT XML

Subcellular Location Biology & Function Interactions Cross-References

General Information

Protein Information
Protein Name	Vesicle-associated membrane protein-associated protein A
Accession Code	Q9P0L0
Gene	VAPA
Organism	Homo sapiens \| Human (Taxonomy: 9606)
Part of Reference Proteome?	Yes
Sequence (Length: 249)
MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGSTVTVSVML QPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPMP KPHSVSLNDTETRKLMEECKRLQGEMMKLSEENRHLRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFI GFFLGKFIL

Structure Viewer (PDB: 2RR3)

Subcellular Location

Description
Endoplasmic reticulum membrane {Experimental EvidencePubMed:10523508, Experimental EvidencePubMed:16143324, Experimental EvidencePubMed:19289470, Experimental EvidencePubMed:25447204, Experimental EvidencePubMed:30741634}; Single-pass type IV membrane protein {Experimental EvidencePubMed:10523508, Experimental EvidencePubMed:19289470}. Cell membrane {Experimental EvidencePubMed:25447204}; Single-pass type IV membrane protein {ECO:0000305}. Cell junction, tight junction {Experimental EvidencePubMed:10523508}. Nucleus membrane {ECO:0000250\|UniProtKB:Q9Z270}. Note=Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells. {Experimental EvidencePubMed:10523508}.
Position in the Nuclear Envelope
Location	Location ID	Description
Nuclear Envelope	SL-0178	The nuclear envelope is a membrane system which surrounds the nucleoplasm of eukaryotic cells. It is composed of the nuclear lamina, nuclear pore complexes and two nuclear membranes. The space between the two membranes is called the nuclear intermembrane space.
Nuclear Membrane	SL-0182	The membrane surrounding the nucleus. This term is used when it is not known if the protein is found in or associated with the inner or outer nuclear membrane.
Membrane Topology
Topology	Source	Annotation Type
Transmembrane	UniProt	Sequence Analysis {ECO:0000255}
Assigned Ontology terms

Cellular Component	Azurophil Granule Membrane (GO:0035577) Bicellular Tight Junction (GO:0005923) Cytosol (GO:0005829) Endoplasmic Reticulum (GO:0005783) Endoplasmic Reticulum Membrane (GO:0005789) Golgi Membrane (GO:0000139) Microtubule Cytoskeleton (GO:0015630) Nuclear Membrane (GO:0031965) Plasma Membrane (GO:0005886) Vesicle (GO:0031982)

Biology & Function

Description
Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites (PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:25447204). With OSBPL3, may regulate ER morphology (PubMed:16143324). May play a role in vesicle trafficking (PubMed:11511104, PubMed:19289470). {Experimental EvidencePubMed:11511104, Experimental EvidencePubMed:16143324, Experimental EvidencePubMed:19289470, Experimental EvidencePubMed:25447204}.
Assigned Ontology terms

Biological Process	Cell Death (GO:0008219) Ceramide Transport (GO:0035627) COPII-Coated Vesicle Budding (GO:0090114) Endoplasmic Reticulum To Golgi Vesicle-Mediated Transport (GO:0006888) Membrane Fusion (GO:0061025) Negative Regulation By Host Of Viral Genome Replication (GO:0044828) Neuron Projection Development (GO:0031175) Phospholipid Transport (GO:0015914) Positive Regulation By Host Of Viral Genome Replication (GO:0044829) Positive Regulation Of I-KappaB Kinase/NF-KappaB Signaling (GO:0043123) Protein Localization To Endoplasmic Reticulum (GO:0070972) Sphingomyelin Biosynthetic Process (GO:0006686) Sterol Transport (GO:0015918) Viral Release From Host Cell (GO:0019076)
Molecular Function	Cadherin Binding (GO:0045296) FFAT Motif Binding (GO:0033149) Microtubule Binding (GO:0008017) Protein Domain Specific Binding (GO:0019904) Protein Heterodimerization Activity (GO:0046982)

Protein-Protein Interactions

Interactions with Nuclear Envelope proteins (27 interactors)

Partner (NucEnvDB)		IntAct	Confidence score
Q5JSH3	WD repeat-containing protein 44	EBI-21550773	0.35
Q6ULP2	Aftiphilin	EBI-21550773	0.35
P16278	Beta-galactosidase	EBI-11120309	0.35
Q9Y6K0	Choline/ethanolaminephosphotransferase 1	EBI-11120309	0.35
Q07065	Cytoskeleton-associated protein 4	EBI-11120309	0.35
P03246	E1B protein, small T-antigen	EBI-11722343	0.35
Q15125	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	EBI-24733627	0.56
P00533	Epidermal growth factor receptor	EBI-4397828	0.71
Q8WYP5	Protein ELYS	EBI-21550773	0.35
P04626	Receptor tyrosine-protein kinase erbB-2	EBI-8770853	0.55
Q9NWT6	Hypoxia-inducible factor 1-alpha inhibitor	EBI-12502476	0.35
Q9P2D3	HEAT repeat-containing protein 5B	EBI-21550773	0.35
P02545	Lamin-A/C	EBI-16795756	0.27
Q9H4L5	Oxysterol-binding protein-related protein 3	EBI-11120309	0.35
Q9BZF3	Oxysterol-binding protein-related protein 6	EBI-11120309	0.35
P22059	Oxysterol-binding protein 1	EBI-11120309	0.74
O15173	Membrane-associated progesterone receptor component 2	EBI-24691023	0.56
P27958	RNA-directed RNA polymerase	EBI-8849923	0.78
Q9WMX2	RNA-directed RNA polymerase	EBI-12738328	0.54
Q03463	RNA-directed RNA polymerase	EBI-8803422	0.67
Q99IB8	RNA-directed RNA polymerase	EBI-8784130	0.56
P01112	GTPase HRas, N-terminally processed	EBI-27045317	0.27
Q8WXH0	Nesprin-2	EBI-21550773	0.35
Q9UMZ2	Synergin gamma	EBI-21550773	0.35
Q9BTV4	Transmembrane protein 43	EBI-11120309	0.35
Q9Y2K6	Ubiquitin carboxyl-terminal hydrolase 20	EBI-2512022	0.40
Q8TEY7	Ubiquitin carboxyl-terminal hydrolase 33	EBI-21550773	0.35
Interactions with other proteins (283 interactors)

Partner (UniProt)		IntAct	Confidence score
P01889	HLA class I histocompatibility antigen, B alpha chain (Human leukocyte antigen B) (HLA-B)	EBI-1077173	0.00
Q96SU4	Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9)	EBI-2514776	0.40
Q99MK9	Ras association domain-containing protein 1 (Protein 123F2)	EBI-2556403	0.56
A0A6L7GZ58	NTPase_I-T domain-containing protein	EBI-2812120	0.00
Q81VJ7	Putative sugar uptake protein BA_0200/GBAA_0200/BAS0200	EBI-2813855	0.00
Q81TU4	UPF0234 protein BA_1166/GBAA_1166/BAS1081	EBI-2819380	0.00
Q81VT8	DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)	EBI-2819368	0.00
A0A6L8PDJ5	Alpha-ketoglutarate permease	EBI-2819418	0.00
A0A0F7RGR7	Amino acid permease family protein	EBI-2819399	0.00
A0A6L7HCN1	Putative membrane protein	EBI-2819425	0.00
A0A6L8PK55	Helicase ATP-binding domain-containing protein	EBI-2819406	0.00
A0A6L7HG64	Molybdopterin molybdenumtransferase (EC 2.10.1.1)	EBI-2819387	0.00
A0A6L8NZ61	Carbon starvation protein A	EBI-2819455	0.00
A0A6L8NYR0	Group-specific protein	EBI-2819437	0.00
Q81JE0	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (EC 4.2.1.59) ((3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase) ((3R)-hydroxymyristoyl-ACP dehydrase) (Beta-hydroxyacyl-ACP dehydratase)	EBI-2819468	0.00
A0A4Y1W7L5	Conserved membrane protein YqhR	EBI-2819444	0.00
Q8CZU2	Putative autotransporter adhesin	EBI-2843966	0.00
Q0WAZ5	Putative membrane protein	EBI-2850711	0.00
Q8D1S0	Putative transport protein, symporter	EBI-2850699	0.00
A0A2U2GZH9	Putative membrane protein	EBI-2850718	0.00
Q5T4F4	Protrudin (Spastic paraplegia 33 protein) (Zinc finger FYVE domain-containing protein 27)	EBI-3894106	0.57
Q96TC7	Regulator of microtubule dynamics protein 3 (RMD-3) (hRMD-3) (Cerebral protein 10) (Protein FAM82A2) (Protein FAM82C) (Protein tyrosine phosphatase-interacting protein 51) (TCPTP-interacting protein 51)	EBI-7415741	0.55
P15336	Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (cAMP response element-binding protein CRE-BP1)	EBI-5529812	0.35
P04578	Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]	EBI-6176669	0.46
P19320	Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106)	EBI-6191076	0.53
P17612	cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)	EBI-6255618	0.53
P22694	cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)	EBI-6255866	0.53
Q13188	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]	EBI-6256382	0.53
Q77M19	V protein	EBI-6270503	0.35
P02751	Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]	EBI-6285956	0.35
Q13043	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]	EBI-6911839	0.35
Q86WH2	Ras association domain-containing protein 3	EBI-6912050	0.35
P35372	Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)	EBI-6918974	0.68
P32300	Delta-type opioid receptor (D-OR-1) (DOR-1) (K56) (MSL-2)	EBI-6926064	0.40
P41145	Kappa-type opioid receptor (K-OR-1) (KOR-1)	EBI-6926066	0.40
Q6PEC3	Protein YIF1B (YIP1-interacting factor homolog B)	EBI-8804473	0.46
O95070	Protein YIF1A (54TMp) (YIP1-interacting factor homolog A)	EBI-8850242	0.60
O95292	Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)	EBI-8840764	0.56
Q9P035	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (hB-ind1) (Protein-tyrosine phosphatase-like A domain-containing protein 1)	EBI-9083284	0.40
Q99614	Tetratricopeptide repeat protein 1 (TPR repeat protein 1)	EBI-9395686	0.53
O95772	STARD3 N-terminal-like protein (MLN64 N-terminal domain homolog)	EBI-9819574	0.46
Q14849	StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3)	EBI-9819322	0.52
P19838	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]	EBI-11322417	0.35
P05412	Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)	EBI-11323169	0.35
P03182	Apoptosis regulator BHRF1 (Early antigen protein R) (EA-R) (Nuclear antigen)	EBI-11721938	0.35
P06460	Probable protein E5A	EBI-11723082	0.35
P06792	Probable protein E5	EBI-11724527	0.35
P0C739	Protein BNLF2a	EBI-11725101	0.35
P69901	Probable protein E5B	EBI-11733364	0.35
A2AUM9	Centrosomal protein of 152 kDa (Cep152)	EBI-10994361	0.35
Q3UJU9	Regulator of microtubule dynamics protein 3 (RMD-3) (mRMD-3) (Protein FAM82A2) (Protein FAM82C)	EBI-11021410	0.35
P60710	Actin, cytoplasmic 1 (Beta-actin) (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]	EBI-11045267	0.35
O95786	Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)	EBI-11120309	0.35
P10644	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1)	EBI-11120309	0.53
Q969M3	Protein YIPF5 (Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5) (Smooth muscle cell-associated protein 5) (SMAP-5) (YIP1 family member 5) (YPT-interacting protein 1 A)	EBI-11120309	0.35
Q96BQ5	Coiled-coil domain-containing protein 127	EBI-11120309	0.35
Q8N4V1	ER membrane protein complex subunit 5 (Membrane magnesium transporter 1) (Transmembrane protein 32)	EBI-11120309	0.35
P47985	Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS) (Ubiquinol-cytochrome c reductase 8 kDa protein)]	EBI-11120309	0.35
Q9ULH0	Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)	EBI-11120309	0.35
P35232	Prohibitin 1	EBI-11120309	0.35
Q5T8D3	Acyl-CoA-binding domain-containing protein 5	EBI-11120309	0.35
Q9UBQ5	Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (Muscle-specific gene M9 protein) (PLAC-24) (eIF-3 p25) (eIF-3 p28)	EBI-11120309	0.35
K7EJC8	Golgi SNAP receptor complex member 1	EBI-11120309	0.35
Q6NZI2	Caveolae-associated protein 1 (Cavin-1) (Polymerase I and transcript release factor)	EBI-11120309	0.35
P28331	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD)	EBI-11120309	0.35
Q9HCK4	Roundabout homolog 2	EBI-11120309	0.35
O95182	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a)	EBI-11120309	0.35
O14653	Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin)	EBI-11120309	0.35
P35610	Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1)	EBI-11120309	0.35
Q8NE86	Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A)	EBI-11120309	0.35
O00461	Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa)	EBI-11120309	0.35
P21796	Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM)	EBI-11120309	0.35
O75306	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 7.1.1.2) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)	EBI-11120309	0.35
P56181	NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (Complex I-9kD) (CI-9kD) (NADH-ubiquinone oxidoreductase 9 kDa subunit) (Renal carcinoma antigen NY-REN-4)	EBI-11120309	0.35
Q13445	Transmembrane emp24 domain-containing protein 1 (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor-binding protein) (p24 family protein gamma-1) (Tp24) (p24gamma1)	EBI-11120309	0.35
P10606	Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase polypeptide Vb)	EBI-11120309	0.35
O00562	Membrane-associated phosphatidylinositol transfer protein 1 (Drosophila retinal degeneration B homolog) (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2)	EBI-11120309	0.35
O43678	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Complex I-B8) (CI-B8) (NADH-ubiquinone oxidoreductase B8 subunit)	EBI-11120309	0.35
Q9BZ71	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (PITPnm 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1)	EBI-11120309	0.35
Q9BXB5	Oxysterol-binding protein-related protein 10 (ORP-10) (OSBP-related protein 10)	EBI-11120309	0.35
Q9NRZ9	Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6)	EBI-11120309	0.35
Q9NX63	MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 3)	EBI-11120309	0.35
O94905	Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)	EBI-11120309	0.35
O75477	Erlin-1 (Endoplasmic reticulum lipid raft-associated protein 1) (Protein KE04) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1) (SPFH domain-containing protein 1)	EBI-11120309	0.35
Q99623	Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)	EBI-11120309	0.35
Q9UBD5	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo)	EBI-11120309	0.35
O75348	V-type proton ATPase subunit G 1 (V-ATPase subunit G 1) (V-ATPase 13 kDa subunit 1) (Vacuolar proton pump subunit G 1) (Vacuolar proton pump subunit M16)	EBI-11120309	0.35
P21281	V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2)	EBI-11120309	0.35
Q14254	Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1)	EBI-11120309	0.35
Q8NC06	Acyl-CoA-binding domain-containing protein 4	EBI-11120309	0.35
O14880	Microsomal glutathione S-transferase 3 (Microsomal GST-3) (Glutathione peroxidase MGST3) (EC 1.11.1.-) (LTC4 synthase MGST3) (EC 4.4.1.20) (Microsomal glutathione S-transferase III) (Microsomal GST-III)	EBI-11120309	0.35
P45880	Voltage-dependent anion-selective channel protein 2 (VDAC-2) (hVDAC2) (Outer mitochondrial membrane protein porin 2)	EBI-11120309	0.35
Q8N1G2	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (hMTr1) (FtsJ methyltransferase domain-containing protein 2) (Interferon-stimulated gene 95 kDa protein) (ISG95)	EBI-11120309	0.35
B7ZAQ6	Golgi pH regulator A (Protein GPR89A) (Putative MAPK-activating protein PM01) (Putative NF-kappa-B-activating protein 90)	EBI-11120309	0.35
O75381	Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14)	EBI-11120309	0.35
P09669	Cytochrome c oxidase subunit 6C (Cytochrome c oxidase polypeptide VIc)	EBI-11120309	0.35
Q8TEW0	Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)	EBI-11120309	0.35
Q03135	Caveolin-1	EBI-11120309	0.35
Q9BXB4	Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)	EBI-11120309	0.35
O95168	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (Complex I-B15) (CI-B15) (NADH-ubiquinone oxidoreductase B15 subunit)	EBI-11120309	0.35
O43920	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (Complex I-15 kDa) (CI-15 kDa) (NADH-ubiquinone oxidoreductase 15 kDa subunit)	EBI-11120309	0.35
P53007	Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Mitochondrial citrate carrier) (CIC) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)	EBI-11120309	0.35
Q92604	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (Acyl-CoA:monoacylglycerol acyltransferase LPGAT1) (EC 2.3.1.22) (Lysophospholipid acyltransferase 7) (LPLAT7) (EC 2.3.1.-) (Stearoyl-CoA:1-lyso-2-acyl-PE acyltransferase)	EBI-11120309	0.35
Q92508	Piezo-type mechanosensitive ion channel component 1 (Membrane protein induced by beta-amyloid treatment) (Mib) (Protein FAM38A)	EBI-11120309	0.35
Q9H089	Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-)	EBI-11120309	0.35
Q9UBH6	Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor)	EBI-11120309	0.35
Q16891	MICOS complex subunit MIC60 (Cell proliferation-inducing gene 4/52 protein) (Mitochondrial inner membrane protein) (Mitofilin) (p87/89)	EBI-11120309	0.35
O95169	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Complex I-ASHI) (CI-ASHI) (NADH-ubiquinone oxidoreductase ASHI subunit)	EBI-11120309	0.35
Q969G5	Caveolae-associated protein 3 (Cavin-3) (Protein kinase C delta-binding protein) (Serum deprivation response factor-related gene product that binds to C-kinase) (hSRBC)	EBI-11120309	0.35
Q9Y2H6	Fibronectin type-III domain-containing protein 3A (Human gene expressed in odontoblasts)	EBI-11120309	0.35
Q16795	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit)	EBI-11120309	0.35
B4E2V5	cDNA FLJ52062, highly similar to Erythrocyte band 7 integral membrane protein	EBI-11120309	0.35
Q99519	Sialidase-1 (EC 3.2.1.18) (Acetylneuraminyl hydrolase) (G9 sialidase) (Lysosomal sialidase) (N-acetyl-alpha-neuraminidase 1)	EBI-11120309	0.35
Q8TBE9	N-acylneuraminate-9-phosphatase (EC 3.1.3.29) (Haloacid dehalogenase-like hydrolase domain-containing protein 4) (Neu5Ac-9-Pase)	EBI-11120309	0.35
O75746	Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (Araceli hiperlarga) (Aralar) (Aralar1) (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12)	EBI-11120309	0.35
Q14573	Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)	EBI-11120309	0.35
P19404	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (EC 7.1.1.2) (NADH-ubiquinone oxidoreductase 24 kDa subunit)	EBI-11120309	0.35
P14854	Cytochrome c oxidase subunit 6B1 (Cytochrome c oxidase subunit VIb isoform 1) (COX VIb-1)	EBI-11120309	0.35
Q8TCJ2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (Source of immunodominant MHC-associated peptides homolog)	EBI-11120309	0.35
Q8NBU5	Outer mitochondrial transmembrane helix translocase (EC 7.4.2.-) (ATPase family AAA domain-containing protein 1) (hATAD1) (Thorase)	EBI-11120309	0.35
P10619	Lysosomal protective protein (EC 3.4.16.5) (Carboxypeptidase C) (Carboxypeptidase L) (Cathepsin A) (Protective protein cathepsin A) (PPCA) (Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain]	EBI-11120309	0.35
Q9P0J0	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Cell death regulatory protein GRIM-19) (Complex I-B16.6) (CI-B16.6) (Gene associated with retinoic and interferon-induced mortality 19 protein) (GRIM-19) (Gene associated with retinoic and IFN-induced mortality 19 protein) (NADH-ubiquinone oxidoreductase B16.6 subunit)	EBI-11120309	0.35
H0YLN8	Non-specific serine/threonine protein kinase (EC 2.7.11.1)	EBI-11120309	0.35
O43181	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (Complex I-18 kDa) (CI-18 kDa) (Complex I-AQDQ) (CI-AQDQ) (NADH-ubiquinone oxidoreductase 18 kDa subunit)	EBI-11120309	0.35
Q9BZ72	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3)	EBI-11120309	0.35
Q9BQB6	Vitamin K epoxide reductase complex subunit 1 (EC 1.17.4.4) (Vitamin K1 2,3-epoxide reductase subunit 1)	EBI-11120309	0.35
O95159	Zinc finger protein-like 1 (Zinc finger protein MCG4)	EBI-11120309	0.35
Q14318	Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)	EBI-11120309	0.35
P28288	ATP-binding cassette sub-family D member 3 (EC 3.1.2.-) (EC 7.6.2.-) (70 kDa peroxisomal membrane protein) (PMP70)	EBI-11120309	0.35
C9J0K6	Sorcin	EBI-11120309	0.35
P61421	V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1)	EBI-11120309	0.35
P38606	V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha)	EBI-11120309	0.35
Q9UJZ1	Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7)	EBI-11120309	0.35
E9PPW7	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 7.1.1.2) (Complex I-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit)	EBI-11120309	0.35
Q7Z6K3	Protein prenyltransferase alpha subunit repeat-containing protein 1	EBI-11120309	0.35
Q04446	1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme)	EBI-11120309	0.35
O75410	Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)	EBI-11120309	0.35
O95299	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit)	EBI-11120309	0.35
Q9NZN5	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)	EBI-11120309	0.35
P31930	Cytochrome b-c1 complex subunit 1, mitochondrial (Complex III subunit 1) (Core protein I) (Ubiquinol-cytochrome-c reductase complex core protein 1)	EBI-11120309	0.35
C9JKI3	Caveolin	EBI-11120309	0.35
P56556	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (LYR motif-containing protein 6) (NADH-ubiquinone oxidoreductase B14 subunit)	EBI-11120309	0.35
Q9NX14	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (CI-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Neuronal protein 17.3) (Np17.3) (p17.3)	EBI-11120309	0.35
P49821	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 7.1.1.2) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) (NADH-ubiquinone oxidoreductase 51 kDa subunit)	EBI-11120309	0.35
Q96N66	Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (1-acylglycerophosphatidylinositol O-acyltransferase) (Bladder and breast carcinoma-overexpressed gene 1 protein) (Leukocyte receptor cluster member 4) (Lysophosphatidylinositol acyltransferase) (LPIAT) (Lyso-PI acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) (h-mboa-7)	EBI-11120309	0.35
Q16718	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit)	EBI-11120309	0.35
P33897	ATP-binding cassette sub-family D member 1 (EC 3.1.2.-) (EC 7.6.2.-) (Adrenoleukodystrophy protein) (ALDP)	EBI-11120309	0.35
Q08380	Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K)	EBI-11120309	0.35
Q9BRQ6	MICOS complex subunit MIC25 (Coiled-coil-helix cristae morphology protein 1) (Coiled-coil-helix-coiled-coil-helix domain-containing protein 6)	EBI-11120309	0.35
P51532	Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)	EBI-11120309	0.35
O75380	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit)	EBI-11120309	0.35
O75955	Flotillin-1	EBI-11120309	0.35
Q9UI09	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (13 kDa differentiation-associated protein) (Complex I-B17.2) (CI-B17.2) (CIB17.2) (NADH-ubiquinone oxidoreductase subunit B17.2)	EBI-11120309	0.35
O15260	Surfeit locus protein 4	EBI-11120309	0.35
Q03518	Antigen peptide transporter 1 (APT1) (EC 7.4.2.-) (ATP-binding cassette sub-family B member 2) (Peptide supply factor 1) (Peptide transporter PSF1) (PSF-1) (Peptide transporter TAP1) (Peptide transporter involved in antigen processing 1) (Really interesting new gene 4 protein) (RING4)	EBI-11120309	0.35
Q5SVZ6	Zinc finger MYM-type protein 1	EBI-11120309	0.35
Q15006	ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35)	EBI-11130215	0.35
Q5T3F8	CSC1-like protein 2 (Transmembrane protein 63B)	EBI-11155257	0.35
Q9Y3E0	Vesicle transport protein GOT1B (Germ cell tumor 2) (Golgi transport 1 homolog B) (Putative NF-kappa-B-activating protein 470) (hGOT1a)	EBI-11161387	0.35
Q96GX1	Tectonic-2	EBI-11375285	0.27
Q9P0N5	Transmembrane protein 216	EBI-11378021	0.27
Q9QXM1	Junction-mediating and -regulatory protein	EBI-11475522	0.35
Q4G0X9	Coiled-coil domain-containing protein 40	EBI-12449318	0.35
P61006	Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)	EBI-11832855	0.35
P05090	Apolipoprotein D (Apo-D) (ApoD)	EBI-24368883	0.72
Q96K78	Adhesion G-protein coupled receptor G7 (G-protein coupled receptor 128)	EBI-24499429	0.56
O00559	Receptor-binding cancer antigen expressed on SiSo cells (Cancer-associated surface antigen RCAS1) (Estrogen receptor-binding fragment-associated gene 9 protein)	EBI-24699966	0.56
Q9Y320	Thioredoxin-related transmembrane protein 2 (Cell proliferation-inducing gene 26 protein) (Thioredoxin domain-containing protein 14)	EBI-24703968	0.56
Q8N661	Lysoplasmalogenase (EC 3.3.2.2) (Transmembrane protein 86B)	EBI-24705292	0.56
Q8N5M9	Protein jagunal homolog 1	EBI-24706911	0.56
P78383	Solute carrier family 35 member B1 (ATP/ADP exchanger ER) (AXER) (Endoplasmic reticulum ATP/ADP translocase) (UDP-galactose transporter-related protein 1) (UGTrel1)	EBI-24709430	0.56
O60669	Monocarboxylate transporter 2 (MCT 2) (Solute carrier family 16 member 7)	EBI-23766238	0.56
Q53TN4	Plasma membrane ascorbate-dependent reductase CYBRD1 (EC 7.2.1.3) (Cytochrome b reductase 1) (Duodenal cytochrome b) (Ferric-chelate reductase 3)	EBI-24718559	0.56
P49447	Transmembrane ascorbate-dependent reductase CYB561 (EC 7.2.1.-) (Cytochrome b-561) (Cytochrome b561)	EBI-24723641	0.56
Q7Z5P4	17-beta-hydroxysteroid dehydrogenase 13 (17-beta-HSD 13) (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 16C member 3) (Short-chain dehydrogenase/reductase 9)	EBI-24742483	0.56
P11912	B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (MB-1 membrane glycoprotein) (Membrane-bound immunoglobulin-associated protein) (Surface IgM-associated protein) (CD antigen CD79a)	EBI-24752923	0.56
Q8NBD8	Transmembrane protein 229B	EBI-24764619	0.56
Q8NBQ5	Estradiol 17-beta-dehydrogenase 11 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17bHSD11) (17betaHSD11) (17-beta-hydroxysteroid dehydrogenase XI) (17-beta-HSD XI) (17betaHSDXI) (Cutaneous T-cell lymphoma-associated antigen HD-CL-03) (CTCL-associated antigen HD-CL-03) (Dehydrogenase/reductase SDR family member 8) (Retinal short-chain dehydrogenase/reductase 2) (retSDR2) (Short chain dehydrogenase/reductase family 16C member 2)	EBI-24786679	0.56
Q9BY50	Signal peptidase complex catalytic subunit SEC11C (EC 3.4.21.89) (Microsomal signal peptidase 21 kDa subunit) (SPase 21 kDa subunit) (SEC11 homolog C) (SEC11-like protein 3) (SPC21)	EBI-24795986	0.56
O15209	Zinc finger and BTB domain-containing protein 22 (Protein BING1) (Zinc finger and BTB domain-containing protein 22A) (Zinc finger protein 297)	EBI-24417267	0.56
Q06432	Voltage-dependent calcium channel gamma-1 subunit (Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma)	EBI-24260483	0.56
Q96LZ7	Regulator of microtubule dynamics protein 2 (RMD-2) (hRMD-2) (Protein FAM82A1)	EBI-24471737	0.56
Q9NS71	Gastrokine-1 (18 kDa antrum mucosa protein) (AMP-18) (Protein CA11)	EBI-24541663	0.56
A0A024R8A9	Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12)	EBI-24560517	0.56
O95214	Leptin receptor overlapping transcript-like 1 (Endospanin-2)	EBI-24641938	0.56
Q13520	Aquaporin-6 (AQP-6) (Aquaporin-2-like) (Kidney-specific aquaporin) (hKID)	EBI-24643376	0.56
Q9NY72	Sodium channel subunit beta-3	EBI-24648989	0.56
Q53FP2	Novel acetylcholine receptor chaperone	EBI-24805194	0.56
Q86VR2	Reticulophagy regulator 3	EBI-25220827	0.56
Q969R2	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4)	EBI-12519574	0.37
Q9BXW6	Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1)	EBI-25616876	0.60
Q9H1P3	Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2)	EBI-12519604	0.37
Q8WXG1	Radical S-adenosyl methionine domain-containing protein 2 (EC 4.2.-.-) (Cytomegalovirus-induced gene 5 protein) (Viperin) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible)	EBI-12738199	0.66
P60033	CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)	EBI-20568535	0.35
O15069	NAC-alpha domain-containing protein 1	EBI-21550773	0.35
Q9UKA4	A-kinase anchor protein 11 (AKAP-11) (A-kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220) (Protein kinase A-anchoring protein 11) (PRKA11)	EBI-21550773	0.35
Q9P0K7	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14)	EBI-21550773	0.35
Q9NZJ5	Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK)	EBI-21550773	0.35
Q9NVV0	Trimeric intracellular cation channel type B (TRIC-B) (TRICB) (Transmembrane protein 38B)	EBI-21550773	0.35
Q9NS23	Ras association domain-containing protein 1	EBI-21550773	0.35
Q9HCK1	DBF4-type zinc finger-containing protein 2	EBI-21550773	0.35
Q9H939	Proline-serine-threonine phosphatase-interacting protein 2 (PEST phosphatase-interacting protein 2)	EBI-21550773	0.35
Q9H8H0	Nucleolar protein 11	EBI-21550773	0.35
Q9H2D6	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin)	EBI-21550773	0.35
Q9BQE3	Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]	EBI-21550773	0.35
Q96RL7	Intermembrane lipid transfer protein VPS13A (Chorea-acanthocytosis protein) (Chorein) (Vacuolar protein sorting-associated protein 13A)	EBI-21550773	0.35
Q8TDY2	RB1-inducible coiled-coil protein 1 (FAK family kinase-interacting protein of 200 kDa) (FIP200)	EBI-21550773	0.35
Q8NHP6	Motile sperm domain-containing protein 2	EBI-21550773	0.35
Q8N9B5	Junction-mediating and -regulatory protein	EBI-21550773	0.35
Q7RTP6	[F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3)	EBI-21550773	0.35
Q7L4E1	Mitoguardin 2 (Protein FAM73B)	EBI-21550773	0.35
Q709C8	Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C)	EBI-21550773	0.35
Q6WCQ1	Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)	EBI-21550773	0.35
Q15042	Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP)	EBI-21550773	0.35
Q05209	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1)	EBI-21550773	0.35
P50453	Serpin B9 (Cytoplasmic antiproteinase 3) (CAP-3) (CAP3) (Peptidase inhibitor 9) (PI-9)	EBI-21550773	0.35
P31321	cAMP-dependent protein kinase type I-beta regulatory subunit	EBI-21550773	0.35
O95067	G2/mitotic-specific cyclin-B2	EBI-21550773	0.35
A6ND36	Protein FAM83G (Protein associated with SMAD1)	EBI-21550773	0.35
Q12765	Secernin-1	EBI-21565088	0.35
P36941	Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III)	EBI-21581171	0.35
A1A519	Protein FAM170A (Zinc finger domain-containing protein) (Zinc finger protein ZNFD)	EBI-21701765	0.35
Q9UKL6	Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2)	EBI-21900698	0.40
O15503	Insulin-induced gene 1 protein (INSIG-1)	EBI-15578834	0.40
Q5ZSD5	SidF, inhibitor of growth family, member 3	EBI-15625386	0.37
O15155	BET1 homolog (hBET1) (Golgi vesicular membrane-trafficking protein p18)	EBI-16788067	0.27
P27824	Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)	EBI-16788621	0.42
Q96I36	Cytochrome c oxidase assembly protein COX14	EBI-16791250	0.27
P11279	Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a)	EBI-16794808	0.27
Q9HBL7	Plasminogen receptor (KT) (Plg-R(KT))	EBI-16797780	0.27
P51151	Ras-related protein Rab-9A	EBI-16798325	0.27
O43493	Trans-Golgi network integral membrane protein 2 (Trans-Golgi network glycoprotein 46) (TGN38 homolog) (hTGN46) (Trans-Golgi network glycoprotein 48) (hTGN48) (Trans-Golgi network glycoprotein 51) (hTGN51) (Trans-Golgi network protein 2)	EBI-16800265	0.27
Q9HCE5	N6-adenosine-methyltransferase non-catalytic subunit (Methyltransferase-like protein 14) (hMETTL14)	EBI-20595531	0.35
P07550	Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)	EBI-20802046	0.37
O75683	Surfeit locus protein 6	EBI-20900511	0.40
Q96CG8	Collagen triple helix repeat-containing protein 1	EBI-20903648	0.40
O43306	Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase)	EBI-20903576	0.40
Q96JK2	DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22)	EBI-20906280	0.40
Q9Y592	Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41) (Renal carcinoma antigen NY-REN-58)	EBI-20907480	0.40
A2A935	Histone-lysine N-methyltransferase PRDM16 (EC 2.1.1.367) (PR domain zinc finger protein 16) (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	EBI-21022882	0.35
P04156	Major prion protein (PrP) (ASCR) (PrP27-30) (PrP33-35C) (CD antigen CD230)	EBI-21014654	0.35
Q9H1C4	Protein unc-93 homolog B1 (Unc-93B1) (hUNC93B1)	EBI-21266770	0.35
O95183	Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)	EBI-21267749	0.35
Q96GC9	Vacuole membrane protein 1 (Transmembrane protein 49)	EBI-21267986	0.35
Q969F8	KiSS-1 receptor (KiSS-1R) (G-protein coupled receptor 54) (G-protein coupled receptor OT7T175) (hOT7T175) (Hypogonadotropin-1) (Kisspeptins receptor) (Metastin receptor)	EBI-21282024	0.40
P03372	Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)	EBI-21301141	0.35
Q9NRI5	Disrupted in schizophrenia 1 protein	EBI-21391954	0.00
P15498	Proto-oncogene vav	EBI-25372968	0.35
P51636	Caveolin-2	EBI-25383812	0.35
O84008	Uncharacterized protein CT_005	EBI-22302433	0.35
O84560	Inner membrane protein	EBI-22302905	0.35
Q640N3	Rho GTPase-activating protein 30 (Rho-type GTPase-activating protein 30)	EBI-25409042	0.35
Q92685	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (EC 2.4.1.258) (Asparagine-linked glycosylation protein 3 homolog) (Dol-P-Man-dependent alpha(1-3)-mannosyltransferase) (Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase) (Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase) (Not56-like protein)	EBI-25468275	0.37
Q8NBM4	Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1)	EBI-25771384	0.35
P01116	GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]	EBI-27041844	0.27
P01111	GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)	EBI-27042293	0.27
F1PAA9	Cadherin-1 (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]	EBI-27079701	0.27
A0A0H3NF08	SPI-2 type III secretion system effector PipB2 (Type III secretion system effector protein, Contributes to Sif formation)	EBI-27055973	0.27
A0A0H3NB75	Pathogenicity island 2 effector protein SseG (Type III secretion system effector protein-modulates the positioning of the SCV)	EBI-27055983	0.27
Q8N488	RING1 and YY1-binding protein (Apoptin-associating protein 1) (APAP-1) (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1)	EBI-27110926	0.35
P43250	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6)	EBI-28935197	0.35
P57059	Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)	EBI-28938560	0.35
Q86UX6	Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase 3)	EBI-28942129	0.35
Q8NG66	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)	EBI-28943501	0.35
Q8NI60	Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3)	EBI-28943519	0.35
Q99640	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)	EBI-28944893	0.35
P42695	Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3)	EBI-28951349	0.35
Q9BXK1	Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor BTEB4) (Transcription factor NSLP2)	EBI-29019783	0.35
O95600	Krueppel-like factor 8 (Basic krueppel-like factor 3) (Zinc finger protein 741)	EBI-29020196	0.35
P08922	Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)	EBI-32719572	0.35
Q16832	Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)	EBI-32720227	0.27
P29320	Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)	EBI-32720767	0.27
P29322	Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)	EBI-32721175	0.27
P21860	Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)	EBI-32721529	0.27
P11362	Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)	EBI-32721578	0.27
P08069	Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]	EBI-32722947	0.27
P06213	Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]	EBI-32723092	0.27
O15146	Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)	EBI-32724025	0.27
Q16288	NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)	EBI-32724526	0.27
P16234	Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)	EBI-32724889	0.27
P07949	Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]	EBI-32725031	0.27
Q04912	Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]	EBI-32725158	0.27
Q01974	Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2)	EBI-32725367	0.27

Cross-References

Database	Links
UNIPROT	Q9P0L0 A6NDZ0 D3DUI3 O75453 Q5U0E7 Q9UBZ2
PDB	2RR3 6TQR
Pfam	PF00635
PROSITE	PS50202
OMIM	605703
DisGeNET	9218

Vesicle-associated membrane protein-associated protein A (Homo sapiens)

General Information

Protein Information

Structure Viewer (PDB: 2RR3)

Subcellular Location

Description Show

Position in the Nuclear Envelope

Membrane Topology

Assigned Ontology terms

Biology & Function

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Assigned Ontology terms

Protein-Protein Interactions

Interactions with Nuclear Envelope proteins (27 interactors)

Interactions with other proteins (283 interactors)

Cross-References

Database

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Description

Description